99 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	CPEB1	Cytoplasmic polyadenylation element binding protein 1. (626 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (745 aa)
	PRKACG	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
	IGF1	IlGF domain-containing protein. (196 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	STAG3	Stromal antigen 3. (1221 aa)
	FBXO5	F-box protein 5. (447 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1235 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
	CDC23	Cell division cycle 23. (597 aa)
	CALML5	Calmodulin like 5. (146 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (469 aa)
	PLK1	Serine/threonine-protein kinase PLK. (603 aa)
	MAPK1	Mitogen-activated protein kinase. (339 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	PTTG2	Pituitary tumor-transforming 2. (196 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1389 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (205 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (668 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
	MAPK12	Mitogen-activated protein kinase. (316 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	CDC16	Cell division cycle 16. (620 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (294 aa)
	FBXO43	F-box protein 43. (708 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	CDC20	Cell division cycle 20. (499 aa)
	PTTG1	PTTG1 regulator of sister chromatid separation, securin. (202 aa)
	ANAPC13	Anaphase promoting complex subunit 13. (74 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	REC8	REC8 meiotic recombination protein. (547 aa)
	SMC3	Structural maintenance of chromosomes protein. (1217 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (597 aa)
	LOC106635345	Uncharacterized protein; Belongs to the SKP1 family. (164 aa)
	RBX1	Ring-box 1. (108 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	PLCZ1	Phosphoinositide phospholipase C. (639 aa)
	CALML4	Calmodulin like 4. (196 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (756 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	CDC26	Cell division cycle 26. (85 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (243 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (599 aa)
	LOC100982423	Uncharacterized protein. (78 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (275 aa)
	CDC27	Cell division cycle 27. (830 aa)
	MAPK11	Mitogen-activated protein kinase. (325 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1056 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (565 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (313 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (149 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	LOC100978515	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (758 aa)
	AR	Androgen receptor. (882 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
	ENSPPAP00000032995	Uncharacterized protein. (188 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (317 aa)
	ENSPPAP00000034531	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (165 aa)
	CALML6	Calmodulin like 6. (181 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2117 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	YWHAQ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (718 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
	SPDYE4	Speedy/RINGO cell cycle regulator family member E4. (237 aa)
	SLK	STE20 like kinase. (1236 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (433 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSPPAP00000033273	ENSPPAP00000023934	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.573
ADCY1	ADCY3	ENSPPAP00000033273	ENSPPAP00000030669	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY4	ENSPPAP00000033273	ENSPPAP00000031100	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.480
ADCY1	ADCY5	ENSPPAP00000033273	ENSPPAP00000025948	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.464
ADCY1	ADCY6	ENSPPAP00000033273	ENSPPAP00000015584	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY1	ADCY7	ENSPPAP00000033273	ENSPPAP00000007130	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.605
ADCY1	ADCY8	ENSPPAP00000033273	ENSPPAP00000028968	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY1	ADCY9	ENSPPAP00000033273	ENSPPAP00000003795	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.712
ADCY1	CALM3	ENSPPAP00000033273	ENSPPAP00000029183	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3; Belongs to the calmodulin family.	0.965
ADCY1	CALML3	ENSPPAP00000033273	ENSPPAP00000006554	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.964
ADCY1	CALML4	ENSPPAP00000033273	ENSPPAP00000020274	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.955
ADCY1	CALML5	ENSPPAP00000033273	ENSPPAP00000005888	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 5.	0.964
ADCY1	CALML6	ENSPPAP00000033273	ENSPPAP00000034585	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.956
ADCY1	CAMK2A	ENSPPAP00000033273	ENSPPAP00000039041	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.912
ADCY1	PRKACA	ENSPPAP00000033273	ENSPPAP00000003342	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.947
ADCY1	PRKACB	ENSPPAP00000033273	ENSPPAP00000017680	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.948
ADCY1	PRKACG	ENSPPAP00000033273	ENSPPAP00000002963	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.959
ADCY2	ADCY1	ENSPPAP00000023934	ENSPPAP00000033273	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.573
ADCY2	ADCY3	ENSPPAP00000023934	ENSPPAP00000030669	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.452
ADCY2	ADCY4	ENSPPAP00000023934	ENSPPAP00000031100	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.455