74 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRDX1	Peroxiredoxin 1. (199 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (739 aa)
	XDH	Xanthine dehydrogenase. (1272 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
	CRAT	Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	DAO-2	DAO domain-containing protein. (71 aa)
	PEX11G	Peroxisomal biogenesis factor 11 gamma. (241 aa)
	PEX11B	Peroxisomal biogenesis factor 11 beta. (259 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	HAO2	Hydroxyacid oxidase 2. (351 aa)
	AGXT	Serine--pyruvate aminotransferase. (392 aa)
	ECH1	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
	PEX3	Peroxisomal biogenesis factor 3. (373 aa)
	PEX13	Peroxisomal biogenesis factor 13. (403 aa)
	CROT	Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
	PXMP4	Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
	PEX7	Peroxisomal biogenesis factor 7. (325 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (740 aa)
	HMGCLL1	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (340 aa)
	PRDX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
	PAOX	Amino_oxidase domain-containing protein. (511 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (749 aa)
	FAR1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (428 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1196 aa)
	PEX2	Peroxisomal biogenesis factor 2. (305 aa)
	MPV17	Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
	PEX10	Peroxisomal biogenesis factor 10. (326 aa)
	NUDT19	Uncharacterized protein. (212 aa)
	ACOT8	Acyl-CoA thioesterase 8. (319 aa)
	PIPOX	Pipecolic acid and sarcosine oxidase. (390 aa)
	HMGCL	3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
	DDO	D-aspartate oxidase. (369 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (698 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (650 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	PEX6	Peroxisomal biogenesis factor 6. (952 aa)
	NUDT12	Nudix hydrolase 12. (462 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (658 aa)
	BAAT	Bile acid-CoA:amino acid N-acyltransferase. (418 aa)
	PEX11A	Peroxisomal biogenesis factor 11 alpha. (247 aa)
	SLC25A17	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
	PEX14	Peroxisomal biogenesis factor 14. (377 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	PEX19	Uncharacterized protein. (299 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (745 aa)
	PXMP2	Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	FAR2	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	MPV17L2	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (206 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (659 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (434 aa)
	ACSL6	AMP-binding domain-containing protein. (714 aa)
	ACAA1-2	Uncharacterized protein. (111 aa)
	PECR	Peroxisomal trans-2-enoyl-CoA reductase. (321 aa)
	MLYCD	Malonyl-CoA decarboxylase. (491 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
	ABCD4	ATP binding cassette subfamily D member 4. (606 aa)
	PMVK	Phosphomevalonate kinase. (192 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1283 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (761 aa)
	PHYH	Phytanoyl-CoA 2-hydroxylase. (338 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
	PEX16	Peroxisomal membrane protein PEX16. (336 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	HACL1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
	GNPAT	Dihydroxyacetone phosphate acyltransferase. (691 aa)
	SLC27A2	Solute carrier family 27 member 2. (620 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (382 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD2	ENSPPAP00000032174	ENSPPAP00000014896	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 2.	0.918
ABCD1	ABCD3	ENSPPAP00000032174	ENSPPAP00000033942	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.959
ABCD1	ABCD4	ENSPPAP00000032174	ENSPPAP00000037208	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 4.	0.627
ABCD1	ACOX1	ENSPPAP00000032174	ENSPPAP00000025791	ATP binding cassette subfamily D member 1.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.540
ABCD1	ACSL1	ENSPPAP00000032174	ENSPPAP00000025336	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 1.	0.535
ABCD1	ACSL3	ENSPPAP00000032174	ENSPPAP00000011182	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 3.	0.532
ABCD1	ACSL4	ENSPPAP00000032174	ENSPPAP00000018085	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 4.	0.507
ABCD1	ACSL5	ENSPPAP00000032174	ENSPPAP00000000729	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 5.	0.520
ABCD1	ACSL6	ENSPPAP00000032174	ENSPPAP00000035131	ATP binding cassette subfamily D member 1.	AMP-binding domain-containing protein.	0.555
ABCD1	AGPS	ENSPPAP00000032174	ENSPPAP00000027597	ATP binding cassette subfamily D member 1.	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.	0.502
ABCD1	ECH1	ENSPPAP00000032174	ENSPPAP00000008755	ATP binding cassette subfamily D member 1.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.400
ABCD1	ECI2	ENSPPAP00000032174	ENSPPAP00000034957	ATP binding cassette subfamily D member 1.	Enoyl-CoA delta isomerase 2.	0.564
ABCD1	MPV17L2	ENSPPAP00000032174	ENSPPAP00000033819	ATP binding cassette subfamily D member 1.	MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.429
ABCD1	PEX11A	ENSPPAP00000032174	ENSPPAP00000028416	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 alpha.	0.656
ABCD1	PEX11B	ENSPPAP00000032174	ENSPPAP00000006154	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 beta.	0.679
ABCD1	PEX11G	ENSPPAP00000032174	ENSPPAP00000004778	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 gamma.	0.558
ABCD1	PEX12	ENSPPAP00000032174	ENSPPAP00000026589	ATP binding cassette subfamily D member 1.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.671
ABCD1	PEX13	ENSPPAP00000032174	ENSPPAP00000009936	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 13.	0.751
ABCD1	PEX14	ENSPPAP00000032174	ENSPPAP00000030433	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 14.	0.688
ABCD1	PEX16	ENSPPAP00000032174	ENSPPAP00000039431	ATP binding cassette subfamily D member 1.	Peroxisomal membrane protein PEX16.	0.674