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GRM8 GRM8 TRPC1 TRPC1 PPP3CB PPP3CB SLC38A3 SLC38A3 PRKACG PRKACG PRKACA PRKACA KCNJ3 KCNJ3 ADCY9 ADCY9 PLCB1 PLCB1 GNG2 GNG2 GRM2 GRM2 PLCB4 PLCB4 MAPK1 MAPK1 GRIA3 GRIA3 GRIN3A GRIN3A GLS GLS ADCY7 ADCY7 GRIN2B GRIN2B GRIA4 GRIA4 SLC38A1 SLC38A1 SLC1A1 SLC1A1 GRIN3B GRIN3B GNGT1 GNGT1 ITPR2 ITPR2 GNGT2 GNGT2 GLS2 GLS2 GNAQ GNAQ GRIA1 GRIA1 PLA2G4E PLA2G4E GRK2 GRK2 GRM5 GRM5 GRK3 GRK3 GRIK3 GRIK3 GNB2 GNB2 SLC17A6 SLC17A6 GRIK4 GRIK4 GNAI1 GNAI1 SLC1A2 SLC1A2 SLC38A2 SLC38A2 ADCY6 ADCY6 GRM7 GRM7 GRIN1 GRIN1 CACNA1C CACNA1C PRKCA PRKCA GNAI2 GNAI2 PRKACB PRKACB GNG3 GNG3 HOMER1 HOMER1 DLGAP1 DLGAP1 SLC1A3 SLC1A3 GNAS GNAS GNAS-2 GNAS-2 GNG8 GNG8 GNG4 GNG4 HOMER2 HOMER2 GRIN2A GRIN2A PLA2G4F PLA2G4F PRKCB PRKCB GRIN2D GRIN2D ADCY2 ADCY2 LOC100989438 LOC100989438 GRIK5 GRIK5 ADCY5 ADCY5 PLD2 PLD2 GNG7 GNG7 GRM6 GRM6 GRIK2 GRIK2 HOMER3 HOMER3 GRM3 GRM3 ADCY8 ADCY8 DLG4 DLG4 GNB1 GNB1 GRIA2 GRIA2 GNAI3 GNAI3 ADCY3 ADCY3 ADCY4 ADCY4 ADCY1 ADCY1 GNB5 GNB5 PLA2G4D PLA2G4D SHANK2 SHANK2 PLCB2 PLCB2 PLCB3 PLCB3 ITPR3 ITPR3 ITPR1 ITPR1 GNG11 GNG11 GNAO1 GNAO1 SLC17A8 SLC17A8 GLUL GLUL SLC17A7 SLC17A7 PPP3CA PPP3CA SLC1A6 SLC1A6 GNB3 GNB3 GRM1 GRM1 PLA2G4A PLA2G4A GRM4 GRM4 PLA2G4C PLA2G4C CACNA1D CACNA1D GNB4 GNB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRM8ANF_receptor domain-containing protein. (184 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SLC38A3Solute carrier family 38 member 3. (504 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
KCNJ3Uncharacterized protein. (308 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1068 aa)
GLSGlutaminase. (565 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
SLC38A1Solute carrier family 38 member 1. (503 aa)
SLC1A1Amino acid transporter. (524 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (880 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GLS2Glutaminase 2. (602 aa)
GNAQG protein subunit alpha q. (313 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
PLA2G4EPhospholipase A2. (868 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (670 aa)
GRM5Glutamate metabotropic receptor 5. (1195 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (891 aa)
GNB2G protein subunit beta 2. (340 aa)
SLC17A6Solute carrier family 17 member 6. (577 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (940 aa)
GNAI1G protein subunit alpha i1. (323 aa)
SLC1A2Amino acid transporter. (574 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2; Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta (By similarity). (506 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
GRM7Glutamate metabotropic receptor 7. (922 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HOMER1Homer scaffold protein 1. (358 aa)
DLGAP1DLG associated protein 1. (977 aa)
SLC1A3Amino acid transporter. (542 aa)
GNASGNAS complex locus. (1043 aa)
GNAS-2Uncharacterized protein. (245 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HOMER2Homer scaffold protein 2. (356 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
PLA2G4FPhospholipase A2. (849 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
GRIN2DUncharacterized protein. (806 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
LOC100989438Uncharacterized protein. (873 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1056 aa)
PLD2Phospholipase. (915 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRM6Glutamate metabotropic receptor 6. (752 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (869 aa)
HOMER3Homer scaffold protein 3. (361 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
GNB1G protein subunit beta 1. (340 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
GNB5G protein subunit beta 5. (395 aa)
PLA2G4DPhospholipase A2. (818 aa)
SHANK2Uncharacterized protein. (1849 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNAO1G protein subunit alpha o1. (354 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
GLULGlutamine synthetase. (373 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SLC1A6Amino acid transporter. (564 aa)
GNB3G protein subunit beta 3. (340 aa)
GRM1Glutamate metabotropic receptor 1. (1194 aa)
PLA2G4APhospholipase A2. (749 aa)
GRM4Glutamate metabotropic receptor 4. (912 aa)
PLA2G4CPhospholipase A2 group IVC. (529 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
GNB4G protein subunit beta 4. (340 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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