STRINGSTRING
CSN2 CSN2 FOXO3 FOXO3 SOCS5 SOCS5 MAPK8 MAPK8 SOCS4 SOCS4 PIK3R3 PIK3R3 SOCS3 SOCS3 FOS FOS TNFRSF11A TNFRSF11A MAPK1 MAPK1 ESR1 ESR1 SOCS7 SOCS7 SOS1 SOS1 GRB2 GRB2 PIK3R2 PIK3R2 PIK3CA PIK3CA SHC3 SHC3 MAP2K1 MAP2K1 AKT2 AKT2 HRAS HRAS MAP2K2 MAP2K2 MAPK12 MAPK12 GCK GCK SHC1 SHC1 PIK3CB PIK3CB ELF5 ELF5 LHCGR LHCGR ESR2 ESR2 NFKB1 NFKB1 RELA RELA SOCS6 SOCS6 CYP17A1 CYP17A1 LHB LHB TNFSF11 TNFSF11 RAF1 RAF1 AKT3 AKT3 PRL PRL MAPK11 MAPK11 IRF1 IRF1 CCND2 CCND2 MAPK13 MAPK13 NRAS NRAS MAPK9 MAPK9 SLC2A2 SLC2A2 CISH CISH STAT1 STAT1 STAT5B STAT5B AKT1 AKT1 SOS2 SOS2 SRC SRC STAT3 STAT3 SOCS2 SOCS2 GSK3B GSK3B MAPK14 MAPK14 SHC4 SHC4 PIK3R1 PIK3R1 STAT5A STAT5A MAPK10 MAPK10 SHC2 SHC2 PRLR PRLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (225 aa)
FOXO3Forkhead box O3. (655 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TNFRSF11ATNF receptor superfamily member 11a. (615 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
SOCS7Suppressor of cytokine signaling 7. (518 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PIK3R2Uncharacterized protein. (663 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
SHC3SHC adaptor protein 3. (501 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa)
MAPK12Mitogen-activated protein kinase. (316 aa)
GCKPhosphotransferase. (463 aa)
SHC1SHC adaptor protein 1. (584 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
ELF5E74 like ETS transcription factor 5. (265 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
ESR2Estrogen receptor 2. (530 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
CYP17A1Uncharacterized protein; Belongs to the cytochrome P450 family. (350 aa)
LHBLuteinizing hormone beta polypeptide. (144 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRLProlactin. (227 aa)
MAPK11Mitogen-activated protein kinase. (325 aa)
IRF1Interferon regulatory factor. (325 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
CISHCytokine inducible SH2 containing protein. (275 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
STAT5BSignal transducer and activator of transcription. (789 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa)
SRCTyrosine-protein kinase. (458 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SHC4SHC adaptor protein 4. (630 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
SHC2Uncharacterized protein. (539 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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