STRINGSTRING
TRPC1 TRPC1 PIK3R3 PIK3R3 KCNJ3 KCNJ3 KCNJ11 KCNJ11 PLCB1 PLCB1 PLCB4 PLCB4 MAPK1 MAPK1 CACNA1I CACNA1I TRPC4 TRPC4 HCN3 HCN3 CACNA1F CACNA1F KCNN1 KCNN1 GABBR2 GABBR2 ITPR2 ITPR2 GNRH1 GNRH1 PIK3R2 PIK3R2 PIK3CA PIK3CA CACNA1G CACNA1G GNAQ GNAQ MAP2K1 MAP2K1 AKT2 AKT2 HRAS HRAS MAP2K2 MAP2K2 KCNN4 KCNN4 CACNA1C CACNA1C PRKCA PRKCA PIK3CB PIK3CB ESR2 ESR2 KCNJ6 KCNJ6 LHB LHB CACNA1H CACNA1H PRKCB PRKCB KCNJ9 KCNJ9 TRPC5 TRPC5 RAF1 RAF1 KCNJ5 KCNJ5 KISS1R KISS1R AKT3 AKT3 NRAS NRAS HCN2 HCN2 GNA11 GNA11 ARRB2 ARRB2 KCNN3 KCNN3 PLCB2 PLCB2 SPP1 SPP1 AKT1 AKT1 CACNA1S CACNA1S PLCB3 PLCB3 ITPR3 ITPR3 ITPR1 ITPR1 HCN1 HCN1 PIK3R1 PIK3R1 GABBR1 GABBR1 CACNA1D CACNA1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
KCNJ3Uncharacterized protein. (308 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2175 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (774 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (570 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (903 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (96 aa)
PIK3R2Uncharacterized protein. (663 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2364 aa)
GNAQG protein subunit alpha q. (313 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
ESR2Estrogen receptor 2. (530 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
LHBLuteinizing hormone beta polypeptide. (144 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2328 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KISS1RG_PROTEIN_RECEP_F1_2 domain-containing protein. (349 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
HCN2Cyclic nucleotide-binding domain-containing protein. (518 aa)
GNA11G protein subunit alpha 11. (319 aa)
ARRB2Arrestin beta 2. (447 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (716 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (883 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (969 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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