STRINGSTRING
SLC2A4 SLC2A4 CD36 CD36 MAPK8 MAPK8 RPS6KB2 RPS6KB2 PIK3R3 PIK3R3 RPS6KA6 RPS6KA6 SOCS3 SOCS3 TNF TNF IRS1 IRS1 TNFRSF1A TNFRSF1A CREB3L4 CREB3L4 SLC27A3 SLC27A3 CPT1B CPT1B CPT1A CPT1A AGT AGT NR1H2 NR1H2 PPP1R3E PPP1R3E PTPN1 PTPN1 GFPT2 GFPT2 PIK3R2 PIK3R2 PIK3CA PIK3CA RPS6KB1 RPS6KB1 PRKAG3 PRKAG3 AKT2 AKT2 PRKCQ PRKCQ ENSPPAP00000011278 ENSPPAP00000011278 PPP1CB PPP1CB TRIB3 TRIB3 CREB3L1 CREB3L1 PYGM PYGM RPS6KA3 RPS6KA3 PRKAG2 PRKAG2 PPP1CC PPP1CC OGA OGA CREB5 CREB5 FOXO1 FOXO1 G6PC G6PC CRTC2 CRTC2 PIK3CB PIK3CB MLXIP MLXIP NFKB1 NFKB1 RELA RELA PPP1R3B PPP1R3B PRKCE PRKCE PRKCD PRKCD PRKAB1 PRKAB1 SREBF1 SREBF1 SLC2A1 SLC2A1 PCK2 PCK2 ACACB ACACB IKBKB IKBKB CREB3 CREB3 PRKCB PRKCB PYGB PYGB CREB3L3 CREB3L3 PPARGC1A PPARGC1A PPARGC1B PPARGC1B PYGL PYGL AKT3 AKT3 PTPN11 PTPN11 IL6 IL6 PRKAA1 PRKAA1 G6PC2 G6PC2 PRKAB2 PRKAB2 MTOR MTOR PCK1 PCK1 MAPK9 MAPK9 MLXIPL MLXIPL RPS6KA2 RPS6KA2 NR1H3 NR1H3 NOS3 NOS3 SLC2A2 SLC2A2 GYS1 GYS1 LOC100995377 LOC100995377 PPARA PPARA PTPRF PTPRF AKT1 AKT1 STAT3 STAT3 SLC27A5 SLC27A5 SLC27A6 SLC27A6 GSK3B GSK3B G6PC3 G6PC3 PRKAG1 PRKAG1 RPS6KA1 RPS6KA1 PPP1R3A PPP1R3A PPP1R3C PPP1R3C SLC27A4 SLC27A4 NFKBIA NFKBIA TBC1D4 TBC1D4 SLC27A1 SLC27A1 PIK3R1 PIK3R1 GYS2 GYS2 PRKCZ PRKCZ CREB3L2 CREB3L2 MAPK10 MAPK10 SLC27A2 SLC27A2 GFPT1 GFPT1 PRKAA2 PRKAA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
SLC27A3Solute carrier family 27 member 3. (811 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (280 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
GFPT2Glutamine-fructose-6-phosphate transaminase 2. (682 aa)
PIK3R2Uncharacterized protein. (663 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (758 aa)
ENSPPAP00000011278Protein kinase domain-containing protein. (351 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
OGAO-GlcNAcase. (946 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (507 aa)
FOXO1Fork-head domain-containing protein. (527 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
CRTC2CREB regulated transcription coactivator 2. (701 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
MLXIPMLX interacting protein. (854 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (819 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (418 aa)
PPARGC1APPARG coactivator 1 alpha. (809 aa)
PPARGC1BPPARG coactivator 1 beta. (997 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
IL6Uncharacterized protein. (198 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MLXIPLMLX interacting protein like. (852 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (453 aa)
NOS3Nitric oxide synthase 3. (997 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
LOC100995377Uncharacterized protein. (557 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1912 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
STAT3Signal transducer and activator of transcription. (781 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
SLC27A6Solute carrier family 27 member 6. (619 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1140 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
SLC27A4Solute carrier family 27 member 4. (647 aa)
NFKBIAANK_REP_REGION domain-containing protein. (456 aa)
TBC1D4TBC1 domain family member 4. (1176 aa)
SLC27A1Solute carrier family 27 member 1. (646 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
PRKAA2Non-specific serine/threonine protein kinase. (542 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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