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KCNE2 KCNE2 KCNJ2 KCNJ2 SSTR2 SSTR2 ATP4B ATP4B KCNJ1 KCNJ1 PRKACG PRKACG SLC26A7 SLC26A7 PRKACA PRKACA KCNK10 KCNK10 ADCY9 ADCY9 PLCB1 PLCB1 CALML5 CALML5 PLCB4 PLCB4 CALML3 CALML3 ADCY7 ADCY7 ITPR2 ITPR2 SST SST MYLK3 MYLK3 GNAQ GNAQ ATP1A4 ATP1A4 MYLK MYLK GAST GAST GNAI1 GNAI1 KCNK2 KCNK2 ADCY6 ADCY6 KCNJ16 KCNJ16 PRKCA PRKCA GNAI2 GNAI2 PRKACB PRKACB KCNJ15 KCNJ15 GNAS GNAS GNAS-2 GNAS-2 CALML4 CALML4 CA2 CA2 HRH2 HRH2 SLC9A4 SLC9A4 ATP1A2 ATP1A2 PRKCB PRKCB ADCY2 ADCY2 KCNQ1 KCNQ1 ATP1B2 ATP1B2 ADCY5 ADCY5 ATP1B1 ATP1B1 ATP4A ATP4A EZR EZR ACTG1 ACTG1 ADCY8 ADCY8 CALM3 CALM3 KCNJ10 KCNJ10 GNAI3 GNAI3 ADCY3 ADCY3 ADCY4 ADCY4 ATP1B3 ATP1B3 ADCY1 ADCY1 ATP1A1 ATP1A1 PLCB2 PLCB2 ATP1B4 ATP1B4 CALML6 CALML6 PLCB3 PLCB3 ITPR3 ITPR3 CFTR CFTR ITPR1 ITPR1 MYLK2 MYLK2 CAMK2A CAMK2A SLC4A2 SLC4A2 SLC9A1 SLC9A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (291 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
SLC26A7Anion exchange transporter. (663 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CALML5Calmodulin like 5. (146 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
SSTSomatostatin. (116 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
GNAQG protein subunit alpha q. (313 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
MYLKMyosin light chain kinase. (1847 aa)
GASTGastrin. (101 aa)
GNAI1G protein subunit alpha i1. (323 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (457 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (375 aa)
GNASGNAS complex locus. (1043 aa)
GNAS-2Uncharacterized protein. (245 aa)
CALML4Calmodulin like 4. (196 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (294 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (397 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
KCNQ1Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (267 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1056 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
EZREzrin. (604 aa)
ACTG1Actin gamma 1. (375 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
KCNJ10IRK domain-containing protein. (207 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (242 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
CALML6Calmodulin like 6. (181 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
SLC4A2Anion exchange protein. (1239 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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