92 items (Pan paniscus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLA2G2A	Phospholipase A(2). (144 aa)
	TRPC1	Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
	CCK	Cholecystokinin. (115 aa)
	SCTR	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	PNLIP	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
	LOC103786316	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	SLC12A2	Solute carrier family 12 member 2. (1091 aa)
	AMY2B	Alpha-amylase. (511 aa)
	LOC100980682	Alpha-amylase. (511 aa)
	CCKAR	Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	RAB3D	RAB3D, member RAS oncogene family. (219 aa)
	LOC100981456	Uncharacterized protein. (317 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa)
	PLA2G2F	Phospholipase A(2). (211 aa)
	ATP2B3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
	GNAQ	G protein subunit alpha q. (313 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
	PLA2G12A	Phospholipase A2 group XIIA. (189 aa)
	PLA2G3	Phospholipase A2 group III. (509 aa)
	CELA2A	Chymotrypsin like elastase 2A; Belongs to the peptidase S1 family. (269 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	CLCA4	Chloride channel accessory 4. (917 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	TPCN2	Two pore segment channel 2. (752 aa)
	PLA2G2D	Phospholipase A(2). (161 aa)
	RHOA	Uncharacterized protein. (206 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
	KCNMA1	Potassium calcium-activated channel subfamily M alpha 1. (1194 aa)
	RAC1	Uncharacterized protein. (224 aa)
	GNAS	GNAS complex locus. (1043 aa)
	GNAS-2	Uncharacterized protein. (245 aa)
	LOC100989777	Uncharacterized protein. (191 aa)
	CA2	Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (294 aa)
	CTRB1	Chymotrypsinogen B1; Belongs to the peptidase S1 family. (263 aa)
	CPB2	Carboxypeptidase B2. (423 aa)
	CEL	Carboxyl ester lipase. (660 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	PRSS3	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
	BST1	Bone marrow stromal cell antigen 1. (332 aa)
	CELA3A	Chymotrypsin like elastase 3A; Belongs to the peptidase S1 family. (232 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
	KCNQ1	Ion_trans domain-containing protein; Belongs to the potassium channel family. (557 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (267 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1056 aa)
	LOC100993013	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	CD38	CD38 molecule. (300 aa)
	PLA2G1B	Phospholipase A(2). (148 aa)
	CTRL	Chymotrypsin like; Belongs to the peptidase S1 family. (264 aa)
	ATP2A1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (873 aa)
	CTRB2	Chymotrypsinogen B2; Belongs to the peptidase S1 family. (263 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	LOC100993827	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (268 aa)
	CLCA2	Chloride channel accessory 2. (943 aa)
	CPB1	Carboxypeptidase B1. (417 aa)
	SCT	Uncharacterized protein. (172 aa)
	CPA1	Carboxypeptidase A1. (420 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	RAB27B	RAB27B, member RAS oncogene family. (218 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	ATP2A3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1017 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (242 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
	CELA2B	Chymotrypsin like elastase 2B; Belongs to the peptidase S1 family. (269 aa)
	SLC4A4	Anion exchange protein. (1100 aa)
	CPA3	Carboxypeptidase A3. (417 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa)
	CPA2	Carboxypeptidase A2. (419 aa)
	CLCA1	Chloride channel accessory 1. (935 aa)
	SLC4A2	Anion exchange protein. (1239 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
	PRSS2	Serine protease 2; Belongs to the peptidase S1 family. (261 aa)
	RYR2	Ryanodine receptor 2. (4948 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSPPAP00000033273	ENSPPAP00000023934	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.573
ADCY1	ADCY3	ENSPPAP00000033273	ENSPPAP00000030669	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY4	ENSPPAP00000033273	ENSPPAP00000031100	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.480
ADCY1	ADCY5	ENSPPAP00000033273	ENSPPAP00000025948	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.464
ADCY1	ADCY6	ENSPPAP00000033273	ENSPPAP00000015584	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.463
ADCY1	ADCY7	ENSPPAP00000033273	ENSPPAP00000007130	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.605
ADCY1	ADCY8	ENSPPAP00000033273	ENSPPAP00000028968	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY1	ADCY9	ENSPPAP00000033273	ENSPPAP00000003795	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.712
ADCY1	GNAS	ENSPPAP00000033273	ENSPPAP00000019582	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.980
ADCY1	GNAS-2	ENSPPAP00000033273	ENSPPAP00000020165	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.902
ADCY1	PLCB1	ENSPPAP00000033273	ENSPPAP00000005635	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.495
ADCY1	PRKCA	ENSPPAP00000033273	ENSPPAP00000017194	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.928
ADCY1	PRKCB	ENSPPAP00000033273	ENSPPAP00000022486	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.908
ADCY2	ADCY1	ENSPPAP00000023934	ENSPPAP00000033273	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.573
ADCY2	ADCY3	ENSPPAP00000023934	ENSPPAP00000030669	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.452
ADCY2	ADCY4	ENSPPAP00000023934	ENSPPAP00000031100	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.455
ADCY2	ADCY5	ENSPPAP00000023934	ENSPPAP00000025948	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.770
ADCY2	ADCY6	ENSPPAP00000023934	ENSPPAP00000015584	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.718
ADCY2	ADCY7	ENSPPAP00000023934	ENSPPAP00000007130	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.456
ADCY2	ADCY8	ENSPPAP00000023934	ENSPPAP00000028968	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.469