STRINGSTRING
PDE1B PDE1B PDE3B PDE3B PRKACG PRKACG PRKACA PRKACA KCNJ3 KCNJ3 DRD1 DRD1 ADCY9 ADCY9 GABRP GABRP GNG2 GNG2 GABRA6 GABRA6 ADCY7 ADCY7 GABRE GABRE GNGT1 GNGT1 GABRG1 GABRG1 GABBR2 GABBR2 GNGT2 GNGT2 GRK5 GRK5 GRK2 GRK2 GRK3 GRK3 GNB2 GNB2 GRK4 GRK4 GNAI1 GNAI1 ADCY6 ADCY6 GABRA3 GABRA3 PRKCA PRKCA GNAI2 GNAI2 PRKACB PRKACB GNG3 GNG3 GABRQ GABRQ GABRA1 GABRA1 KCNJ6 KCNJ6 GNAS GNAS PDE4C PDE4C GNAS-2 GNAS-2 PDE4B PDE4B GNG8 GNG8 GNG4 GNG4 ADORA1 ADORA1 GABRR2 GABRR2 PDE10A PDE10A PRKCB PRKCB GABRD GABRD KCNJ9 KCNJ9 ADCY2 ADCY2 KCNJ5 KCNJ5 ADCY5 ADCY5 PDE1A PDE1A PDE11A PDE11A GABRR3 GABRR3 PDE7B PDE7B GABRG3 GABRG3 GNG7 GNG7 PDE7A PDE7A PDE8B PDE8B GABRA5 GABRA5 ADCY8 ADCY8 PDE2A PDE2A GNB1 GNB1 SLC32A1 SLC32A1 GABRR1 GABRR1 GNAI3 GNAI3 ADCY3 ADCY3 ADCY4 ADCY4 ARRB2 ARRB2 ADCY1 ADCY1 GNB5 GNB5 GABRB3 GABRB3 GNG11 GNG11 GRK6 GRK6 GABRB1 GABRB1 GABRA4 GABRA4 CACNA1B CACNA1B GNAO1 GNAO1 PDE4D PDE4D OPRM1 OPRM1 PDE3A PDE3A PDE1C PDE1C GABBR1 GABBR1 GNB3 GNB3 PDE8A PDE8A GNB4 GNB4 PDE4A PDE4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE1BPDEase domain-containing protein. (218 aa)
PDE3BPhosphodiesterase. (1112 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
KCNJ3Uncharacterized protein. (308 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (903 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (670 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
GNB2G protein subunit beta 2. (340 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (577 aa)
GNAI1G protein subunit alpha i1. (323 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
GNASGNAS complex locus. (1043 aa)
PDE4CPhosphodiesterase. (713 aa)
GNAS-2Uncharacterized protein. (245 aa)
PDE4BPhosphodiesterase. (736 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (461 aa)
PDE10APhosphodiesterase. (856 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1056 aa)
PDE1APhosphodiesterase. (572 aa)
PDE11APhosphodiesterase. (922 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
PDE7BPhosphodiesterase. (502 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE7APhosphodiesterase. (456 aa)
PDE8BPhosphodiesterase. (788 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PDE2APhosphodiesterase. (941 aa)
GNB1G protein subunit beta 1. (340 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ARRB2Arrestin beta 2. (447 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
GNB5G protein subunit beta 5. (395 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (396 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (558 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
CACNA1BUncharacterized protein. (491 aa)
GNAO1G protein subunit alpha o1. (354 aa)
PDE4DPhosphodiesterase. (706 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (492 aa)
PDE3APhosphodiesterase. (1141 aa)
PDE1CPhosphodiesterase. (713 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (969 aa)
GNB3G protein subunit beta 3. (340 aa)
PDE8APhosphodiesterase. (824 aa)
GNB4G protein subunit beta 4. (340 aa)
PDE4APhosphodiesterase. (793 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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