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| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa) |
| | LOC106634335 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IFNA17 | Interferon alpha 17. (189 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | IFNA6 | Interferon alpha 6. (189 aa) |
| | LOC100972005 | Uncharacterized protein. (198 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | IFNA10 | Interferon alpha 10. (189 aa) |
| | NFKBIB | ANK_REP_REGION domain-containing protein. (270 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3. (497 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (558 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | NLRX1 | NLR family member X1. (975 aa) |
| | KPNA6 | Importin subunit alpha; Functions in nuclear protein import. (554 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (496 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | LOC100979649 | Ig-like domain-containing protein. (170 aa) |
| | NXT1 | Nuclear transport factor 2 like export factor 1. (140 aa) |
| | IFNA2 | Interferon alpha 2. (170 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (347 aa) |
| | LOC103785895 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (110 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (540 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (266 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | TLR7 | Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | LOC100993508 | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa) |
| | PIK3R2 | Uncharacterized protein. (663 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RAB11B | Uncharacterized protein. (221 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PABPN1L | Poly(A) binding protein nuclear 1 like, cytoplasmic. (278 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (241 aa) |
| | BCL2L2-PABPN1 | BCL2L2-PABPN1 readthrough. (333 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | LOC100986750 | Ig-like domain-containing protein. (287 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa) |
| | OAS1 | 2',5'-oligoadenylate synthetase 1. (401 aa) |
| | NXT2 | Nuclear transport factor 2 like export factor 2. (197 aa) |
| | RAB11A | RAB11A, member RAS oncogene family. (216 aa) |
| | IRF7 | Interferon regulatory factor 7. (516 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (403 aa) |
| | NXF3 | Nuclear RNA export factor 3. (531 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | ENSPPAP00000016834 | Uncharacterized protein. (195 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) |
| | ADAR | A to I editase domain-containing protein. (193 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (489 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | IFNA7 | Interferon alpha 7. (189 aa) |
| | KPNA5 | Importin subunit alpha; Functions in nuclear protein import. (530 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | IFNA21 | Interferon alpha 21. (189 aa) |
| | ICAM1 | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (537 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | CDK6 | Protein kinase domain-containing protein. (84 aa) |
| | PRSS3 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | MX1 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (719 aa) |
| | FADD | Death domain-containing protein. (144 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa) |
| | TMPRSS4 | Transmembrane serine protease 4; Belongs to the peptidase S1 family. (422 aa) |
| | IFNAR2 | Uncharacterized protein. (519 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | NUP98 | Nucleoporin 98. (1807 aa) |
| | LOC100990091 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (431 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | IL6 | Uncharacterized protein. (198 aa) |
| | IRF3 | Interferon regulatory factor 3. (452 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | ENSPPAP00000025320 | NTF2 domain-containing protein. (406 aa) |
| | CARD17 | Caspase recruitment domain family member 17. (110 aa) |
| | CIITA | Class II major histocompatibility complex transactivator. (1131 aa) |
| | LOC100993013 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa) |
| | TMPRSS11D | Transmembrane protease serine; Belongs to the peptidase S1 family. (418 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | RAE1 | Ribonucleic acid export 1. (361 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (289 aa) |
| | ACTG1 | Actin gamma 1. (375 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | LOC100993827 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (268 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (261 aa) |
| | MHC-DMB | Ig-like domain-containing protein. (276 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | HLA-DQA2 | Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa) |
| | HNRNPUL1 | Heterogeneous nuclear ribonucleoprotein U like 1. (798 aa) |
| | CXCL10 | C-X-C motif chemokine. (96 aa) |
| | CREBBP | CREB binding protein. (2414 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | LOC100993847 | Ig-like domain-containing protein. (270 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1025 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | TYK2 | Tyrosine-protein kinase. (1190 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (361 aa) |
| | STAT1 | Signal transducer and activator of transcription. (759 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (218 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | TPSD1 | Tryptase delta 1; Belongs to the peptidase S1 family. (228 aa) |
| | KPNA7 | Importin subunit alpha; Functions in nuclear protein import. (516 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (469 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 1. (261 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 2. (264 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | NXF1 | Nuclear RNA export factor 1. (619 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (456 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (736 aa) |
| | PLG | Plasminogen; Belongs to the peptidase S1 family. (822 aa) |
| | LOC100978423 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (282 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1082 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | PRSS2 | Serine protease 2; Belongs to the peptidase S1 family. (261 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (529 aa) |
