STRINGSTRING
BAD BAD FZD5 FZD5 EGF EGF COL1A1 COL1A1 COL4A6 COL4A6 MAML3 MAML3 RB1 RB1 MAML1 MAML1 IFNA17 IFNA17 HLA-C HLA-C RPS6KB2 RPS6KB2 IFNA14 IFNA14 IFNA6 IFNA6 LFNG LFNG ATP6V1G1 ATP6V1G1 LOC100972005 LOC100972005 IFNA5 IFNA5 IFNA10 IFNA10 WNT4 WNT4 WNT8A WNT8A PIK3R3 PIK3R3 WNT6 WNT6 WNT11 WNT11 IFNA8 IFNA8 LOC100990258 LOC100990258 WNT5B WNT5B IRF9 IRF9 PRKACG PRKACG SLC9A3R1 SLC9A3R1 PRKACA PRKACA IFNAR1 IFNAR1 LAMA3 LAMA3 TBK1 TBK1 JAK1 JAK1 PPP2R5A PPP2R5A NOTCH3 NOTCH3 ATP6V1D ATP6V1D COL6A5 COL6A5 PPP2R1A PPP2R1A TNF TNF TNFRSF1A TNFRSF1A ITGB4 ITGB4 TBPL1 TBPL1 THBS1 THBS1 IKBKG IKBKG CSNK1A1L CSNK1A1L ITGB5 ITGB5 IFNA2 IFNA2 CREB3L4 CREB3L4 PPP2R2D PPP2R2D UBR4 UBR4 DVL1 DVL1 MAGI1 MAGI1 PPP2R5E PPP2R5E MAPK1 MAPK1 VWF VWF E2F1 E2F1 ATP6V1B1 ATP6V1B1 WNT1 WNT1 COL4A1 COL4A1 WNT2B WNT2B COL2A1 COL2A1 ITGA6 ITGA6 LLGL1 LLGL1 ITGA9 ITGA9 WNT5A WNT5A SOS1 SOS1 RHEB RHEB ATM ATM COL6A1 COL6A1 NFX1 NFX1 PARD6G PARD6G CCND3 CCND3 TRAF3 TRAF3 GRB2 GRB2 PIK3R2 PIK3R2 PIK3CA PIK3CA WNT16 WNT16 RPS6KB1 RPS6KB1 LAMB3 LAMB3 FASLG FASLG FZD9 FZD9 MAP2K1 MAP2K1 CCNE2 CCNE2 AKT2 AKT2 HRAS HRAS LAMB1 LAMB1 TP53 TP53 CRB3 CRB3 PPP2R5D PPP2R5D LLGL2 LLGL2 CHD4 CHD4 MAP2K2 MAP2K2 SCRIB SCRIB TERT TERT PTGER4 PTGER4 PSMC1 PSMC1 BAK1 BAK1 CREB3L1 CREB3L1 HEY1 HEY1 LAMA2 LAMA2 CDKN1B CDKN1B HEYL HEYL CASP3 CASP3 COL6A2 COL6A2 PPP2CA PPP2CA TCIRG1 TCIRG1 NOTCH2 NOTCH2 WNT7A WNT7A ATP6V1C1 ATP6V1C1 PPP2R3C PPP2R3C ITGB3 ITGB3 NOTCH4 NOTCH4 WNT2 WNT2 ISG15 ISG15 FZD7 FZD7 CREB5 CREB5 ITGA10 ITGA10 ITGA11 ITGA11 FOXO1 FOXO1 TCF7L1 TCF7L1 LAMA5 LAMA5 ITGA8 ITGA8 CDC42 CDC42 COL4A3 COL4A3 LAMA1 LAMA1 AXIN1 AXIN1 DVL2 DVL2 HLA-G HLA-G TLR3 TLR3 TBP TBP COL9A3 COL9A3 COL4A2 COL4A2 ENSPPAP00000016834 ENSPPAP00000016834 PIK3CB PIK3CB LOC100974009 LOC100974009 PRKACB PRKACB NFKB1 NFKB1 ATP6V0A4 ATP6V0A4 HDAC1 HDAC1 MX2 MX2 FZD3 FZD3 APC APC RELA RELA PPP2R5B PPP2R5B EP300 EP300 ATP6V1G2 ATP6V1G2 ATP6V0D2 ATP6V0D2 TBPL2 TBPL2 GNAS GNAS ATP6V1E2 ATP6V1E2 IFNA7 IFNA7 WNT9B WNT9B HDAC2 HDAC2 GNAS-2 GNAS-2 IFNA21 IFNA21 Papa-A Papa-A WNT3A WNT3A TNC TNC HES7 HES7 DLG1 DLG1 BCAP31 BCAP31 ITGA3 ITGA3 HES2 HES2 MAML2 MAML2 PXN PXN LAMC1 LAMC1 TSC2 TSC2 PRKCI PRKCI AXIN2 AXIN2 HEY2 HEY2 IKBKB IKBKB LAMC3 LAMC3 CREB3 CREB3 TCF7 TCF7 CDK6 CDK6 JAG1 JAG1 MX1 MX1 LAMB2 LAMB2 CREB3L3 CREB3L3 TNR TNR ATP6V0A1 ATP6V0A1 RELN RELN FADD FADD EIF2AK2 EIF2AK2 THBS4 THBS4 IFNAR2 IFNAR2 PPP2R2A PPP2R2A RAF1 RAF1 FZD6 FZD6 TSC1 TSC1 CTNNB1 CTNNB1 WNT10B WNT10B AKT3 AKT3 PPP2CB PPP2CB LAMC2 LAMC2 COL4A5 COL4A5 TRADD TRADD ITGA1 ITGA1 IRF3 IRF3 FAS FAS ITGAV ITGAV OASL OASL COL9A1 COL9A1 ITGA7 ITGA7 ATP6AP1 ATP6AP1 IRF1 IRF1 MTOR MTOR ITGA4 ITGA4 WNT7B WNT7B CCND2 CCND2 EIF4EBP1 EIF4EBP1 ATP6V0A2 ATP6V0A2 MPP5 MPP5 CDK4 CDK4 VTN VTN RBL2 RBL2 ATP6V0E1 ATP6V0E1 RBPJL RBPJL PDGFRB PDGFRB COL4A4 COL4A4 WNT3 WNT3 ITGB7 ITGB7 CDKN1A CDKN1A ATP6V1E1 ATP6V1E1 UBE3A UBE3A COL6A6 COL6A6 PARD6A PARD6A CHUK CHUK NRAS NRAS MFNG MFNG HLA-E HLA-E TUBG2 TUBG2 PARD6B PARD6B COL6A3 COL6A3 ATP6V1H ATP6V1H CREBBP CREBBP LAMB4 LAMB4 PSEN1 PSEN1 ITGB1 ITGB1 IBSP IBSP PARD3 PARD3 IKBKE IKBKE ENSPPAP00000031810 ENSPPAP00000031810 PPP2R3A PPP2R3A TYK2 TYK2 RFNG RFNG PPP2R2C PPP2R2C LAMA4 LAMA4 LOC100995377 LOC100995377 CCNA2 CCNA2 NOTCH1 NOTCH1 TNN TNN DLG3 DLG3 PATJ PATJ ATP6V0B ATP6V0B STAT1 STAT1 ITGA2B ITGA2B WNT8B WNT8B FZD4 FZD4 BAX BAX THBS2 THBS2 SPP1 SPP1 AKT1 AKT1 WNT9A WNT9A DLG2 DLG2 SOS2 SOS2 COMP COMP GSK3B GSK3B PKM PKM ITGA5 ITGA5 ITGB6 ITGB6 WNT10A WNT10A FN1 FN1 ATP6V0C ATP6V0C HES3 HES3 ATP6V1A ATP6V1A DVL3 DVL3 RBPJ RBPJ PIK3R1 PIK3R1 COL1A2 COL1A2 CHAD CHAD COL9A2 COL9A2 CCNA1 CCNA1 TADA3 TADA3 PRKCZ PRKCZ CREB3L2 CREB3L2 ATR ATR PPP2R2B PPP2R2B PTGS2 PTGS2 ATP6V1B2 ATP6V1B2 ITGB8 ITGB8 ITGA2 ITGA2 THBS3 THBS3 EGFR EGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BADBCL2 associated agonist of cell death. (168 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
COL4A6Collagen type IV alpha 6 chain. (1705 aa)
MAML3Mastermind like transcriptional coactivator 3. (935 aa)
RB1RB transcriptional corepressor 1. (911 aa)
MAML1Mastermind like transcriptional coactivator 1. (911 aa)
IFNA17Interferon alpha 17. (189 aa)
HLA-CMajor histocompatibility complex, class I, C; Belongs to the MHC class I family. (397 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
IFNA14Interferon alpha 14. (189 aa)
IFNA6Interferon alpha 6. (189 aa)
LFNGUncharacterized protein. (306 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
LOC100972005Uncharacterized protein. (198 aa)
IFNA5Interferon alpha 5. (189 aa)
IFNA10Interferon alpha 10. (189 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
IFNA8Interferon alpha 8. (189 aa)
LOC100990258V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
IRF9Interferon regulatory factor 9. (392 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (558 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
TBK1TANK binding kinase 1. (729 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
NOTCH3Notch receptor 3. (1981 aa)
ATP6V1DUncharacterized protein. (192 aa)
COL6A5Collagen type VI alpha 5 chain. (2598 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ITGB4Integrin beta. (1821 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
THBS1Thrombospondin 1. (1173 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (803 aa)
IFNA2Interferon alpha 2. (170 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (395 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5183 aa)
DVL1Dishevelled segment polarity protein 1. (674 aa)
MAGI1Uncharacterized protein. (1129 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (469 aa)
MAPK1Mitogen-activated protein kinase. (339 aa)
VWFVon Willebrand factor. (2813 aa)
E2F1E2F transcription factor 1. (397 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
COL2A1Uncharacterized protein. (1313 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1096 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1064 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1020 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa)
RHEBUncharacterized protein. (173 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
COL6A1Collagen type VI alpha 1 chain. (1015 aa)
NFX1Nuclear transcription factor, X-box binding 1. (1120 aa)
PARD6GPar-6 family cell polarity regulator gamma. (333 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PIK3R2Uncharacterized protein. (663 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
LAMB3Laminin subunit beta 3. (1171 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (517 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
CRB3Crumbs cell polarity complex component 3. (125 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (668 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1047 aa)
CHD4Uncharacterized protein. (1914 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa)
SCRIBScribble planar cell polarity protein. (1656 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1040 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (327 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
COL6A2Collagen type VI alpha 2 chain. (998 aa)
PPP2CASerine/threonine-protein phosphatase. (294 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
NOTCH2Notch receptor 2. (2254 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (814 aa)
NOTCH4Notch receptor 4. (2001 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (507 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1178 aa)
FOXO1Fork-head domain-containing protein. (527 aa)
TCF7L1Transcription factor 7 like 1. (560 aa)
LAMA5Laminin subunit alpha 5. (3648 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
CDC42Uncharacterized protein. (191 aa)
COL4A3Collagen type IV alpha 3 chain. (1641 aa)
LAMA1Laminin subunit alpha 1. (3104 aa)
AXIN1Axin 1. (862 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
HLA-GMajor histocompatibility complex, class I, G; Belongs to the MHC class I family. (355 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
TBPTATA-box binding protein. (357 aa)
COL9A3Collagen type IX alpha 3 chain. (657 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
ENSPPAP00000016834Uncharacterized protein. (195 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
LOC100974009Uncharacterized protein. (184 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (782 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
MX2MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
EP300E1A binding protein p300. (2411 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
TBPL2TATA-box binding protein like 2. (375 aa)
GNASGNAS complex locus. (1043 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
IFNA7Interferon alpha 7. (189 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (495 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (510 aa)
GNAS-2Uncharacterized protein. (245 aa)
IFNA21Interferon alpha 21. (189 aa)
Papa-AIGc1 domain-containing protein; Belongs to the MHC class I family. (406 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
TNCTenascin C. (2201 aa)
HES7BHLH domain-containing protein. (129 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
BCAP31Uncharacterized protein. (246 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
HES2Hes family bHLH transcription factor 2. (173 aa)
MAML2Mastermind like transcriptional coactivator 2. (1153 aa)
PXNUncharacterized protein. (1087 aa)
LAMC1Laminin subunit gamma 1. (1609 aa)
TSC2TSC complex subunit 2. (1807 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
AXIN2Axin 2. (843 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
LAMC3Laminin subunit gamma 3. (1559 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
TCF7HMG box domain-containing protein. (391 aa)
CDK6Protein kinase domain-containing protein. (84 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
MX1Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (662 aa)
LAMB2Laminin subunit beta 2. (1780 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (418 aa)
TNRTenascin R. (1360 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
RELNReelin. (3460 aa)
FADDDeath domain-containing protein. (144 aa)
EIF2AK2Eukaryotic translation initiation factor 2-alpha kinase 2. (552 aa)
THBS4Thrombospondin 4. (870 aa)
IFNAR2Uncharacterized protein. (519 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
TSC1TSC complex subunit 1. (1164 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
COL4A5Collagen type IV alpha 5 chain. (1664 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
IRF3Interferon regulatory factor 3. (452 aa)
FASFas cell surface death receptor. (335 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
OASL2'-5'-oligoadenylate synthetase like. (514 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
IRF1Interferon regulatory factor. (325 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
VTNVitronectin. (478 aa)
RBL2RB transcriptional corepressor like 2. (1139 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (517 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
COL4A4Collagen type IV alpha 4 chain. (1690 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (802 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ATP6V1E1ATPase H+ transporting V1 subunit E1. (226 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (867 aa)
COL6A6Collagen type VI alpha 6 chain. (2241 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (719 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (352 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (466 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
COL6A3Uncharacterized protein. (2527 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
CREBBPCREB binding protein. (2414 aa)
LAMB4Laminin subunit beta 4. (1746 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
IBSPIntegrin binding sialoprotein. (316 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ENSPPAP00000031810MHC_I-like_Ag-recog domain-containing protein. (194 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
RFNGUncharacterized protein. (205 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (535 aa)
LAMA4Laminin subunit alpha 4. (1823 aa)
LOC100995377Uncharacterized protein. (557 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
NOTCH1Notch receptor 1. (2573 aa)
TNNTenascin N. (1299 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (748 aa)
PATJPATJ crumbs cell polarity complex component. (1800 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (261 aa)
STAT1Signal transducer and activator of transcription. (759 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
BAXBCL2 associated X, apoptosis regulator. (218 aa)
THBS2Thrombospondin 2. (1172 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
AKT1Non-specific serine/threonine protein kinase. (501 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
DLG2Discs large MAGUK scaffold protein 2. (939 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa)
COMPCartilage oligomeric matrix protein. (762 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1046 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (414 aa)
FN1Fibronectin 1. (2477 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
HES3Hes family bHLH transcription factor 3. (185 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (618 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (499 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
CHADChondroadherin. (359 aa)
COL9A2Collagen type IX alpha 2 chain. (689 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
TADA3Transcriptional adaptor 3. (432 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2614 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (525 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (757 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
THBS3Thrombospondin 3. (956 aa)
EGFRReceptor protein-tyrosine kinase. (1201 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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