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| | BCL2L1 | BCL2 like 1. (233 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | LOC106634335 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa) |
| | ELOC | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | IFNA17 | Interferon alpha 17. (189 aa) |
| | HLA-C | Major histocompatibility complex, class I, C; Belongs to the MHC class I family. (397 aa) |
| | CALR | Calreticulin. (417 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa) |
| | IFNA6 | Interferon alpha 6. (189 aa) |
| | LOC100972005 | Uncharacterized protein. (198 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | IFNA10 | Interferon alpha 10. (189 aa) |
| | APOBEC3B | Uncharacterized protein. (490 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | APOBEC3C | Apolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | CHEK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa) |
| | IFNA2 | Interferon alpha 2. (170 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | ELOB | Uncharacterized protein. (104 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | CALML5 | Calmodulin like 5. (146 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | TAPBP | TAP binding protein. (466 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (963 aa) |
| | CD3G | CD3g molecule. (182 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | LOC103785895 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (110 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1394 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1507 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (508 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) |
| | PIK3R2 | Uncharacterized protein. (663 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) |
| | GNAQ | G protein subunit alpha q. (313 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (932 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (509 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (241 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (808 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (316 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (785 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | GNAI1 | G protein subunit alpha i1. (323 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (975 aa) |
| | LOC100994688 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | HLA-G | Major histocompatibility complex, class I, G; Belongs to the MHC class I family. (355 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (844 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) |
| | STING1 | Stimulator of interferon protein. (379 aa) |
| | ENSPPAP00000016834 | Uncharacterized protein. (195 aa) |
| | LOC106635345 | Uncharacterized protein; Belongs to the SKP1 family. (164 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | CD3E | CD3e molecule. (207 aa) |
| | BCL2 | BCL2 apoptosis regulator. (193 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | RAC1 | Uncharacterized protein. (224 aa) |
| | IFNA7 | Interferon alpha 7. (189 aa) |
| | APOBEC3G-2 | DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase- dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamin [...] (413 aa) |
| | IFNA21 | Interferon alpha 21. (189 aa) |
| | CALML4 | Calmodulin like 4. (196 aa) |
| | LOC100989777 | Uncharacterized protein. (191 aa) |
| | Papa-A | IGc1 domain-containing protein; Belongs to the MHC class I family. (406 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (461 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | AP1B1 | AP complex subunit beta. (947 aa) |
| | PXN | Uncharacterized protein. (1087 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (724 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (669 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | CUL5 | Cullin 5; Belongs to the cullin family. (775 aa) |
| | CD4 | CD4 molecule. (458 aa) |
| | FADD | Death domain-containing protein. (144 aa) |
| | BST2 | Uncharacterized protein. (185 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1147 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | IRF3 | Interferon regulatory factor 3. (452 aa) |
| | WEE1 | Protein kinase domain-containing protein. (432 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (200 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PAK4 | P21 (RAC1) activated kinase 4. (590 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (336 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (317 aa) |
| | CALM3 | Calmodulin 3; Belongs to the calmodulin family. (149 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (719 aa) |
| | LOC100987164 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (352 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | SAMHD1 | SAM domain and HD domain-containing protein 1. (626 aa) |
| | GNA11 | G protein subunit alpha 11. (319 aa) |
| | ENSPPAP00000031810 | MHC_I-like_Ag-recog domain-containing protein. (194 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (408 aa) |
| | CCDC125 | Coiled-coil domain containing 125. (486 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (493 aa) |
| | GNB5 | G protein subunit beta 5. (395 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (218 aa) |
| | LIMK2 | LIM domain kinase 2. (684 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa) |
| | LIMK1 | LIM domain kinase 1. (677 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (912 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1064 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (423 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (456 aa) |
| | CFL1 | Cofilin 1; Belongs to the actin-binding proteins ADF family. (204 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (424 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (736 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) |
| | AP1M2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (425 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2614 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | CD247 | CD247 molecule. (163 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (680 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
