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| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1463 aa) |
| | NANOG | Putative homeobox protein NANOG2; Probable transcriptional regulator; Belongs to the Nanog homeobox family. (305 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (352 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (484 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (803 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (339 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (917 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa) |
| | LUM | Lumican. (338 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1318 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1389 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2712 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | PIK3R2 | Uncharacterized protein. (663 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1062 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (517 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | ENSPPAP00000011278 | Protein kinase domain-containing protein. (351 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (392 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (316 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | HPSE2 | Heparanase 2 (inactive). (537 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (814 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | CTSL | Cathepsin L; Belongs to the peptidase C1 family. (333 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa) |
| | LOC100977376 | RRM domain-containing protein. (407 aa) |
| | FLNB | Filamin B. (2633 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (1026 aa) |
| | ANK1 | Ankyrin 1. (1897 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (839 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (812 aa) |
| | RHOA | Uncharacterized protein. (206 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (625 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (388 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (771 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | RAC1 | Uncharacterized protein. (224 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2276 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (495 aa) |
| | TFAP4 | Transcription factor AP-4. (337 aa) |
| | LOC100989777 | Uncharacterized protein. (191 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | RRAS | RAS related. (176 aa) |
| | PXN | Uncharacterized protein. (1087 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (402 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) |
| | MSN | Moesin. (591 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (812 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1344 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa) |
| | FLNC | Filamin C. (2725 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa) |
| | PLAU | Plasminogen activator, urokinase. (431 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (766 aa) |
| | HOXD10 | Homeobox D10. (410 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (325 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (828 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (636 aa) |
| | VTN | Vitronectin. (478 aa) |
| | EZR | Ezrin. (604 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | ACTG1 | Actin gamma 1. (375 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (810 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (334 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (247 aa) |
| | HPSE | Heparanase. (543 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1413 aa) |
| | ANK2 | Ankyrin 2. (3957 aa) |
| | CBL | Cbl proto-oncogene. (906 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (359 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (968 aa) |
| | ANK3 | Ankyrin 3. (4364 aa) |
| | MMP2 | Matrix metallopeptidase 2. (664 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa) |
| | CD63 | Tetraspanin. (238 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2685 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1325 aa) |
| | RDX | Radixin. (609 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2700 aa) |
| | STAT3 | Signal transducer and activator of transcription. (781 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1046 aa) |
| | TWIST1 | BHLH domain-containing protein. (138 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4369 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (414 aa) |
| | FN1 | Fibronectin 1. (2477 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1386 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (260 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PPP1R12C | Protein phosphatase 1 regulatory subunit. (707 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | PTCH1 | Patched 1. (1446 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (736 aa) |
| | CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1274 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | RRAS2 | Uncharacterized protein. (169 aa) |
| | ELK1 | ETS transcription factor ELK1. (428 aa) |
| | HSPB2 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa) |
| | PLAUR | Plasminogen activator, urokinase receptor. (335 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1201 aa) |
