STRINGSTRING
LOC100985978 LOC100985978 H2AC6 H2AC6 H2AC1 H2AC1 LOC100975795 LOC100975795 LOC103783476 LOC103783476 H3-3A H3-3A C8G C8G IL10 IL10 LOC100982497 LOC100982497 H2BC5 H2BC5 CTSG CTSG H2AC14 H2AC14 H2AW H2AW H2BC10 H2BC10 ENSPPAP00000003652 ENSPPAP00000003652 H2AC16 H2AC16 TNF TNF H2BC1 H2BC1 H2AC21 H2AC21 LOC100979649 LOC100979649 H3-4 H3-4 H2BC18 H2BC18 LOC100980195 LOC100980195 LOC100987642 LOC100987642 LOC100992822 LOC100992822 H2AC20 H2AC20 H2BC9 H2BC9 H2BC11 H2BC11 LOC100981154 LOC100981154 H2AJ H2AJ H2BC13 H2BC13 LOC100985433 LOC100985433 H2AC7 H2AC7 H2BC14 H2BC14 H2BC3 H2BC3 H2BU1 H2BU1 GRIN2B GRIN2B HLA-DOB HLA-DOB ENSPPAP00000008696 ENSPPAP00000008696 C1QC C1QC MACROH2A2 MACROH2A2 LOC100993508 LOC100993508 ENSPPAP00000009755 ENSPPAP00000009755 MACROH2A1 MACROH2A1 LOC100986750 LOC100986750 FCGR2A FCGR2A C8A C8A LOC100969533 LOC100969533 H2AZ1 H2AZ1 HLA-DPA1 HLA-DPA1 LOC100970329 LOC100970329 C5 C5 LOC100988452 LOC100988452 LOC100985638 LOC100985638 C7 C7 CD86 CD86 GRIN2A GRIN2A C1R C1R CD28 CD28 C6 C6 C3 C3 SNRPB SNRPB HLA-DOA HLA-DOA C9 C9 H2AZ2 H2AZ2 ACTN1 ACTN1 MHC-DMB MHC-DMB HLA-DQA2 HLA-DQA2 LOC100993847 LOC100993847 SNRPD3 SNRPD3 C1QB C1QB CD80 CD80 C8B C8B CD40 CD40 FCGR1A FCGR1A ACTN4 ACTN4 LOC103785316 LOC103785316 HLA-DQB1 HLA-DQB1 HLA-DQB2 HLA-DQB2 HLA-DPB1 HLA-DPB1 HLA-DRA HLA-DRA LOC100988917 LOC100988917 IFNG IFNG SNRPD1 SNRPD1 CD40LG CD40LG SSB SSB C1S C1S TRIM21 TRIM21 RO60 RO60
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100985978Histone H3; Belongs to the histone H3 family. (136 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC100975795Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC103783476Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H3-3AHistone H3; Belongs to the histone H3 family. (136 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
IL10Interleukin 10. (178 aa)
LOC100982497Histone H2A; Belongs to the histone H2A family. (128 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
H2AC14Histone H2A; Belongs to the histone H2A family. (128 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
H2BC10Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSPPAP00000003652Histone H2A; Belongs to the histone H2A family. (129 aa)
H2AC16Histone H2A; Belongs to the histone H2A family. (130 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC100979649Ig-like domain-containing protein. (170 aa)
H3-4Histone cluster 3 H3. (136 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100980195Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC100987642Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100992822Histone H2A; Belongs to the histone H2A family. (115 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2BC9Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100981154Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100985433Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (266 aa)
ENSPPAP00000008696Ig-like domain-containing protein. (147 aa)
C1QCComplement C1q C chain. (245 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC100993508Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
ENSPPAP00000009755Ig-like domain-containing protein. (116 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC100986750Ig-like domain-containing protein. (287 aa)
FCGR2AFc fragment of IgG receptor IIa. (316 aa)
C8AComplement C8 alpha chain. (584 aa)
LOC100969533Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
LOC100970329Peptidase S1 domain-containing protein. (145 aa)
C5Complement C5. (1676 aa)
LOC100988452Uncharacterized protein. (1725 aa)
LOC100985638Histone H2B; Belongs to the histone H2B family. (167 aa)
C7Complement C7. (843 aa)
CD86CD86 molecule. (329 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (704 aa)
CD28CD28 molecule. (220 aa)
C6Complement C6. (934 aa)
C3Complement C3. (1614 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
C9Complement C9. (559 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
ACTN1Actinin alpha 1. (914 aa)
MHC-DMBIg-like domain-containing protein. (276 aa)
HLA-DQA2Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
LOC100993847Ig-like domain-containing protein. (270 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
C1QBComplement C1q B chain. (253 aa)
CD80CD80 molecule. (288 aa)
C8BComplement C8 beta chain. (591 aa)
CD40CD40 molecule. (277 aa)
FCGR1AUncharacterized protein. (368 aa)
ACTN4Actinin alpha 4. (931 aa)
LOC103785316Ig-like domain-containing protein. (221 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (261 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (264 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC100988917Histone domain-containing protein; Belongs to the histone H2B family. (153 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
SSBSmall RNA binding exonuclease protection factor La. (408 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (780 aa)
TRIM21Tripartite motif containing 21. (475 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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