12 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MOG	Myelin oligodendrocyte glycoprotein. (295 aa)
	NES	NES isoform 1; Belongs to the intermediate filament family. (1620 aa)
	CNP	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa)
	PLP1	Proteolipid protein 1. (277 aa)
	CD22-2	B-cell receptor CD22. (626 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (505 aa)
	OLIG1	OLIG1 isoform 2. (272 aa)
	OLIG2	OLIG2 isoform 1. (323 aa)
	ENSPTRP00000079007	annotation not available (323 aa)
	OLIG1-2	OLIG1 isoform 1. (272 aa)
	MBP	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (304 aa)
	RBFOX3	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (373 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD22-2	CNP	ENSPTRP00000048802	ENSPTRP00000015650	B-cell receptor CD22.	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	0.684
CD22-2	ENSPTRP00000079007	ENSPTRP00000048802	ENSPTRP00000079007	B-cell receptor CD22.	annotation not available	0.435
CD22-2	GFAP	ENSPTRP00000048802	ENSPTRP00000062393	B-cell receptor CD22.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.461
CD22-2	MBP	ENSPTRP00000048802	ENSPTRP00000091696	B-cell receptor CD22.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).	0.895
CD22-2	MOG	ENSPTRP00000048802	ENSPTRP00000080071	B-cell receptor CD22.	Myelin oligodendrocyte glycoprotein.	0.822
CD22-2	OLIG1	ENSPTRP00000048802	ENSPTRP00000062464	B-cell receptor CD22.	OLIG1 isoform 2.	0.503
CD22-2	OLIG2	ENSPTRP00000048802	ENSPTRP00000069533	B-cell receptor CD22.	OLIG2 isoform 1.	0.435
CD22-2	PLP1	ENSPTRP00000048802	ENSPTRP00000038073	B-cell receptor CD22.	Proteolipid protein 1.	0.721
CNP	CD22-2	ENSPTRP00000015650	ENSPTRP00000048802	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	B-cell receptor CD22.	0.684
CNP	ENSPTRP00000079007	ENSPTRP00000015650	ENSPTRP00000079007	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	annotation not available	0.534
CNP	GFAP	ENSPTRP00000015650	ENSPTRP00000062393	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.692
CNP	MBP	ENSPTRP00000015650	ENSPTRP00000091696	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).	0.791
CNP	MOG	ENSPTRP00000015650	ENSPTRP00000080071	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Myelin oligodendrocyte glycoprotein.	0.665
CNP	NES	ENSPTRP00000015650	ENSPTRP00000002483	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	NES isoform 1; Belongs to the intermediate filament family.	0.573
CNP	OLIG1	ENSPTRP00000015650	ENSPTRP00000062464	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	OLIG1 isoform 2.	0.504
CNP	OLIG2	ENSPTRP00000015650	ENSPTRP00000069533	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	OLIG2 isoform 1.	0.534
CNP	PLP1	ENSPTRP00000015650	ENSPTRP00000038073	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Proteolipid protein 1.	0.667
CNP	RBFOX3	ENSPTRP00000015650	ENSPTRP00000093937	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.554
ENSPTRP00000079007	CD22-2	ENSPTRP00000079007	ENSPTRP00000048802	annotation not available	B-cell receptor CD22.	0.435
ENSPTRP00000079007	CNP	ENSPTRP00000079007	ENSPTRP00000015650	annotation not available	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	0.534