node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP2 | KCNJ1 | ENSPTRP00000071517 | ENSPTRP00000063071 | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Potassium voltage-gated channel subfamily J member 1. | 0.549 |
AQP2 | SCNN1B | ENSPTRP00000071517 | ENSPTRP00000013457 | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | 0.477 |
AQP2 | SLC12A3 | ENSPTRP00000071517 | ENSPTRP00000013899 | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | SLC12A3 isoform 1. | 0.569 |
AQP2 | SLC26A4 | ENSPTRP00000071517 | ENSPTRP00000033528 | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.586 |
KCNJ1 | AQP2 | ENSPTRP00000063071 | ENSPTRP00000071517 | Potassium voltage-gated channel subfamily J member 1. | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.549 |
KCNJ1 | SCNN1B | ENSPTRP00000063071 | ENSPTRP00000013457 | Potassium voltage-gated channel subfamily J member 1. | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | 0.601 |
KCNJ1 | SLC12A3 | ENSPTRP00000063071 | ENSPTRP00000013899 | Potassium voltage-gated channel subfamily J member 1. | SLC12A3 isoform 1. | 0.858 |
KCNJ1 | SLC26A4 | ENSPTRP00000063071 | ENSPTRP00000033528 | Potassium voltage-gated channel subfamily J member 1. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.400 |
SCNN1B | AQP2 | ENSPTRP00000013457 | ENSPTRP00000071517 | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.477 |
SCNN1B | KCNJ1 | ENSPTRP00000013457 | ENSPTRP00000063071 | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | Potassium voltage-gated channel subfamily J member 1. | 0.601 |
SCNN1B | SLC12A3 | ENSPTRP00000013457 | ENSPTRP00000013899 | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | SLC12A3 isoform 1. | 0.737 |
SLC12A3 | AQP2 | ENSPTRP00000013899 | ENSPTRP00000071517 | SLC12A3 isoform 1. | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.569 |
SLC12A3 | KCNJ1 | ENSPTRP00000013899 | ENSPTRP00000063071 | SLC12A3 isoform 1. | Potassium voltage-gated channel subfamily J member 1. | 0.858 |
SLC12A3 | SCNN1B | ENSPTRP00000013899 | ENSPTRP00000013457 | SLC12A3 isoform 1. | Amiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] | 0.737 |
SLC12A3 | SLC26A4 | ENSPTRP00000013899 | ENSPTRP00000033528 | SLC12A3 isoform 1. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.489 |
SLC26A4 | AQP2 | ENSPTRP00000033528 | ENSPTRP00000071517 | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.586 |
SLC26A4 | KCNJ1 | ENSPTRP00000033528 | ENSPTRP00000063071 | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Potassium voltage-gated channel subfamily J member 1. | 0.400 |
SLC26A4 | SLC12A3 | ENSPTRP00000033528 | ENSPTRP00000013899 | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | SLC12A3 isoform 1. | 0.489 |