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| | IL22RA1 | Interleukin 22 receptor subunit alpha 1. (574 aa) |
| | CSF3R | CSF3R isoform 3. (836 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (862 aa) |
| | IL6R | Interleukin 6 receptor. (442 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | IL20 | IL20 isoform 1. (176 aa) |
| | IL24 | IL24 isoform 5. (207 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (272 aa) |
| | CNTF | Ciliary neurotrophic factor. (200 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) |
| | IL26 | IL26 isoform 1. (171 aa) |
| | IL22 | IL22 isoform 1. (179 aa) |
| | ENSPTRP00000012851 | annotation not available (343 aa) |
| | IL4R | IL4R isoform 2. (827 aa) |
| | CTF1 | Cardiotrophin 1. (201 aa) |
| | GH1 | Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (271 aa) |
| | IFNL3 | IFNL3 isoform 2. (196 aa) |
| | IFNL1 | Interferon lambda 1. (200 aa) |
| | IL11 | IL11 isoform 1. (199 aa) |
| | IFNAR1 | Interferon (Alpha, beta and omega) receptor 1. (558 aa) |
| | LIF | Leukemia inhibitory factor (Cholinergic differentiation factor). (202 aa) |
| | OSM | OSM isoform 1. (252 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor, beta, low-affinity (Granulocyte-macrophage). (904 aa) |
| | IL2RB | Interleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). (551 aa) |
| | IL5RA | Interleukin 5 receptor subunit alpha. (423 aa) |
| | IL20RB | Interleukin 20 receptor subunit beta. (311 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa) |
| | OSMR | Oncostatin M receptor. (979 aa) |
| | IL31RA | Interleukin 31 receptor A. (764 aa) |
| | IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. (152 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | ENSPTRP00000029460 | Interleukin 5. (134 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa) |
| | IL9 | IL9 isoform 1. (144 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | PRL | PRL isoform 1. (227 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) |
| | IFNA21 | Interferon alpha 21. (189 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | IFNE | Interferon, epsilon. (208 aa) |
| | CNTFR | CNTFR isoform 1. (372 aa) |
| | IL13RA2 | Interleukin 13 receptor subunit alpha 2. (393 aa) |
| | IL13RA1 | Interleukin 13 receptor subunit alpha 1. (429 aa) |
| | CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | IFNLR1 | IFNLR1 isoform 2. (521 aa) |
| | CSF2RA | CSF2RA isoform 11. (215 aa) |
| | IL10RB | Interleukin 10 receptor, beta. (325 aa) |
| | IL13-2 | Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages. (146 aa) |
| | IL12RB1 | IL12RB1 isoform 1. (662 aa) |
| | IL2RG | IL2RG isoform 1. (369 aa) |
| | TYK2 | Tyrosine-protein kinase. (1184 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (489 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X4. (519 aa) |
| | GH1-2 | Chorionic somatomammotropin A2. (222 aa) |
| | IRF9 | Interferon regulatory factor 9. (391 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | IL20RA | Interleukin 20 receptor subunit alpha. (553 aa) |
| | IL21R | IL21R isoform 1. (538 aa) |
| | ENSPTRP00000061970 | annotation not available (325 aa) |
| | IFNAR2-2 | Interferon alpha and beta receptor subunit 2. (519 aa) |
| | THPO | THPO isoform 1. (353 aa) |
| | IL6ST | Interleukin 6 signal transducer (Gp130, oncostatin M receptor). (918 aa) |
| | CRLF2 | CRLF2 isoform 1. (372 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | IL6 | Interleukin 6 (Interferon, beta 2). (234 aa) |
| | IFNA17 | IFNA17 isoform 1. (189 aa) |
| | IL23R | IL23R isoform 1. (629 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | IL4-2 | Interleukin 4. (153 aa) |
| | TSLP | TSLP isoform 1. (159 aa) |
| | IL19 | IL19 isoform 1. (215 aa) |
| | GHR | Growth hormone receptor. (645 aa) |
| | MPL | MPL proto-oncogene, thrombopoietin receptor. (646 aa) |
| | IL15RA | IL15RA isoform 11. (353 aa) |
| | GALT | Interleukin-11 receptor subunit alpha precursor. (783 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | ENSPTRP00000077294 | annotation not available (558 aa) |
| | CK820_G0056611 | IL3RA isoform 1. (278 aa) |
| | LIFR | Leukemia inhibitory factor receptor alpha. (1097 aa) |
| | IL13RA2-2 | Interleukin 13 receptor subunit alpha 2. (380 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (179 aa) |
| | CK820_G0014527 | IFNA13 isoform 2. (198 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (578 aa) |
| | IL31 | IL31 isoform 1. (164 aa) |
| | LOC741747 | IFNA7 isoform 1. (189 aa) |
| | CLCF1 | Cardiotrophin-like cytokine factor 1 isoform X1. (225 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | LOC742651 | IFNA1 isoform 1. (195 aa) |
| | STAT1 | Signal transducer and activator of transcription. (758 aa) |
| | IFNGR2-2 | IFNGR2 isoform 6. (302 aa) |
| | STAT2 | Signal transducer and activator of transcription. (851 aa) |
| | IFNW1 | IFNW1 isoform 1. (200 aa) |
