16 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
	CASQ1	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
	STAC3	SH3 and cysteine rich domain 3. (364 aa)
	JSRP1	Junctional sarcoplasmic reticulum protein 1. (331 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	JPH1	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
	ASPH	ASPH isoform 1. (762 aa)
	TRDN	TRDN isoform 1. (730 aa)
	JPH4	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
	RYR2	RYR2 isoform 1. (4941 aa)
	SRI	SRI isoform 1. (205 aa)
	SRI-2	SRI isoform 5. (237 aa)
	CK820_G0030361	RYR1 isoform 5. (4901 aa)
	RYR3	Ryanodine receptor 3. (4873 aa)
	RYR1	RYR1 isoform 3. (5037 aa)
	SYPL2	Synaptophysin like 2. (272 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPH	CASQ1	ENSPTRP00000053155	ENSPTRP00000002593	ASPH isoform 1.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.982
ASPH	CASQ2	ENSPTRP00000053155	ENSPTRP00000001966	ASPH isoform 1.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.982
ASPH	CK820_G0030361	ENSPTRP00000053155	ENSPTRP00000090805	ASPH isoform 1.	RYR1 isoform 5.	0.670
ASPH	FKBP1B	ENSPTRP00000053155	ENSPTRP00000020110	ASPH isoform 1.	Peptidylprolyl isomerase.	0.774
ASPH	JPH1	ENSPTRP00000053155	ENSPTRP00000053135	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.669
ASPH	JPH4	ENSPTRP00000053155	ENSPTRP00000059066	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.604
ASPH	JSRP1	ENSPTRP00000053155	ENSPTRP00000017390	ASPH isoform 1.	Junctional sarcoplasmic reticulum protein 1.	0.516
ASPH	RYR1	ENSPTRP00000053155	ENSPTRP00000092559	ASPH isoform 1.	RYR1 isoform 3.	0.931
ASPH	RYR2	ENSPTRP00000053155	ENSPTRP00000064508	ASPH isoform 1.	RYR2 isoform 1.	0.979
ASPH	RYR3	ENSPTRP00000053155	ENSPTRP00000090974	ASPH isoform 1.	Ryanodine receptor 3.	0.911
ASPH	STAC3	ENSPTRP00000053155	ENSPTRP00000008716	ASPH isoform 1.	SH3 and cysteine rich domain 3.	0.475
ASPH	SYPL2	ENSPTRP00000053155	ENSPTRP00000093783	ASPH isoform 1.	Synaptophysin like 2.	0.480
ASPH	TRDN	ENSPTRP00000053155	ENSPTRP00000058505	ASPH isoform 1.	TRDN isoform 1.	0.998
CASQ1	ASPH	ENSPTRP00000002593	ENSPTRP00000053155	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	ASPH isoform 1.	0.982
CASQ1	CASQ2	ENSPTRP00000002593	ENSPTRP00000001966	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.907
CASQ1	CK820_G0030361	ENSPTRP00000002593	ENSPTRP00000090805	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	RYR1 isoform 5.	0.446
CASQ1	JPH1	ENSPTRP00000002593	ENSPTRP00000053135	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.582
CASQ1	JPH4	ENSPTRP00000002593	ENSPTRP00000059066	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.484
CASQ1	JSRP1	ENSPTRP00000002593	ENSPTRP00000017390	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctional sarcoplasmic reticulum protein 1.	0.644
CASQ1	RYR1	ENSPTRP00000002593	ENSPTRP00000092559	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	RYR1 isoform 3.	0.968