STRINGSTRING
PLK3 PLK3 SASS6 SASS6 CEP164 CEP164 CEP83 CEP83 CENPJ CENPJ PIBF1 PIBF1 CEP128 CEP128 TTBK2 TTBK2 CCP110 CCP110 KIAA0753 KIAA0753 CEP131 CEP131 LRRC45 LRRC45 CEP76 CEP76 CCDC68 CCDC68 CEP89 CEP89 CEP63 CEP63 CEP135 CEP135 PLK4 PLK4 SCLT1 SCLT1 PLK2 PLK2 TDRP TDRP PCM1 PCM1 CNTLN CNTLN PCNT PCNT AKAP9 AKAP9 CNTRL CNTRL KIF24 KIF24 CEP97 CEP97 CDK5RAP2 CDK5RAP2 CEP192 CEP192 CEP295 CEP295 CROCC CROCC CCDC14 CCDC14 CEP152 CEP152 NIN NIN STIL STIL CCDC120 CCDC120 ENSPTRP00000091433 ENSPTRP00000091433 ENSPTRP00000093880 ENSPTRP00000093880
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLK3Serine/threonine-protein kinase PLK. (673 aa)
SASS6Spindle assembly 6 homolog. (658 aa)
CEP164Centrosomal protein 164kDa. (1459 aa)
CEP83Coiled-coil domain containing 41. (701 aa)
CENPJCentromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. Required for the recruitment of CEP295 to the proximal end of new-born [...] (1338 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
CEP128Centrosomal protein 128. (1094 aa)
TTBK2TTBK2 isoform 2; Belongs to the intermediate filament family. (1649 aa)
CCP110CCP110 isoform 2. (1012 aa)
KIAA0753KIAA0753 isoform 1. (967 aa)
CEP1315-azacytidine induced 1. (1083 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
CEP76Centrosomal protein 76kDa. (659 aa)
CCDC68Coiled-coil domain containing 68. (335 aa)
CEP89CEP89 isoform 2. (784 aa)
CEP63Centrosomal protein 63kDa. (703 aa)
CEP135Centrosomal protein 135kDa. (1140 aa)
PLK4Polo-like kinase 4. (970 aa)
SCLT1Sodium channel and clathrin linker 1. (688 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
TDRPTestis development related protein. (198 aa)
PCM1Pericentriolar material 1. (2024 aa)
CNTLNCentlein, centrosomal protein. (1406 aa)
PCNTPCNT isoform 1. (3271 aa)
AKAP9A kinase (PRKA) anchor protein (Yotiao) 9. (3908 aa)
CNTRLCentrosomal protein 110kDa. (2325 aa)
KIF24Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1399 aa)
CEP97Centrosomal protein 97kDa. (865 aa)
CDK5RAP2CDK5 regulatory subunit-associated protein 2; Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of [...] (1903 aa)
CEP192Centrosomal protein 192. (2537 aa)
CEP295Centrosomal protein 295. (2604 aa)
CROCCCROCC isoform 1. (2017 aa)
CCDC14CCDC14 isoform 12. (926 aa)
CEP152Centrosomal protein 152kDa. (1710 aa)
NINNIN isoform 1. (2133 aa)
STILSTIL centriolar assembly protein. (1288 aa)
CCDC120CCDC120 isoform 4. (661 aa)
ENSPTRP00000091433T-complex protein 10A homolog isoform X1. (167 aa)
ENSPTRP00000093880annotation not available (101 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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