50 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POU4F1	POU domain protein. (350 aa)
	NES	NES isoform 1; Belongs to the intermediate filament family. (1620 aa)
	ATOH7	Atonal bHLH transcription factor 7. (152 aa)
	EMX2	Empty spiracles homeobox 2. (252 aa)
	NKX6-2	NKX6-2 isoform 1. (276 aa)
	DBX2	Developing brain homeobox 2. (339 aa)
	FOXN4	FOXN4 isoform 2. (517 aa)
	PDX1	Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element [...] (283 aa)
	INSM2	INSM transcriptional repressor 2. (568 aa)
	VSX2	VSX2 isoform 1. (380 aa)
	IRX6	Iroquois homeobox 6. (445 aa)
	FOXA3	FOXA3 isoform 2. (350 aa)
	GBX2	Gastrulation brain homeobox 2. (348 aa)
	NKX2-2	NKX2-2 isoform 1. (273 aa)
	GSX2	GSX2 isoform 2. (304 aa)
	NKX6-1	NKX6-1 isoform 2. (367 aa)
	POU4F2	POU domain protein. (406 aa)
	NEUROG1	NEUROG1 isoform 1. (237 aa)
	NEUROD6	Neurogenic differentiation factor. (337 aa)
	PAX4	PAX4 isoform 1. (351 aa)
	MAP2	Microtubule-associated protein. (1827 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (894 aa)
	RIPPLY3	RIPPLY3 isoform 3. (189 aa)
	SP8	Sp8 transcription factor. (507 aa)
	EMX1	Empty spiracles homeobox 1. (290 aa)
	NEUROG3	NEUROG3 isoform 1. (214 aa)
	SOX1	SOX1 isoform 1. (391 aa)
	NEUROD4	Neurogenic differentiation factor. (331 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	ENSPTRP00000065099	annotation not available (337 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	DBX1	Developing brain homeobox 1. (345 aa)
	ENSPTRP00000071463	LOW QUALITY PROTEIN: chondroitin sulfate proteoglycan 4. (205 aa)
	ONECUT1	One cut domain family member. (465 aa)
	NR2F2	Nuclear receptor subfamily 2, group F, member 2. (414 aa)
	ENSPTRP00000079007	annotation not available (323 aa)
	FEZF2	FEZ family zinc finger 2. (463 aa)
	OLIG1-2	OLIG1 isoform 1. (272 aa)
	SATB2	DNA-binding protein SATB. (733 aa)
	HNF1B	HNF1 homeobox B. (557 aa)
	PTF1A	Pancreas associated transcription factor 1a. (328 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	NEUROG2	NEUROG2 isoform 1. (272 aa)
	HNF1A	HNF1 homeobox A. (662 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	NR2F1	Nuclear receptor subfamily 2 group F member 1. (423 aa)
	CUX2	Homeobox protein cut-like. (1489 aa)
	FOXA2	FOXA2 isoform 1. (464 aa)
	RBFOX3	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (373 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH7	FOXN4	ENSPTRP00000004403	ENSPTRP00000009196	Atonal bHLH transcription factor 7.	FOXN4 isoform 2.	0.522
ATOH7	PAX6	ENSPTRP00000004403	ENSPTRP00000065705	Atonal bHLH transcription factor 7.	PAX6 isoform 13.	0.475
ATOH7	POU4F1	ENSPTRP00000004403	ENSPTRP00000000774	Atonal bHLH transcription factor 7.	POU domain protein.	0.465
ATOH7	POU4F2	ENSPTRP00000004403	ENSPTRP00000028307	Atonal bHLH transcription factor 7.	POU domain protein.	0.644
ATOH7	VSX2	ENSPTRP00000004403	ENSPTRP00000011084	Atonal bHLH transcription factor 7.	VSX2 isoform 1.	0.611
BCL11B	CUX2	ENSPTRP00000052505	ENSPTRP00000089985	BAF chromatin remodeling complex subunit BCL11B.	Homeobox protein cut-like.	0.516
BCL11B	EMX1	ENSPTRP00000052505	ENSPTRP00000057829	BAF chromatin remodeling complex subunit BCL11B.	Empty spiracles homeobox 1.	0.405
BCL11B	NES	ENSPTRP00000052505	ENSPTRP00000002483	BAF chromatin remodeling complex subunit BCL11B.	NES isoform 1; Belongs to the intermediate filament family.	0.475
BCL11B	NR2F1	ENSPTRP00000052505	ENSPTRP00000088485	BAF chromatin remodeling complex subunit BCL11B.	Nuclear receptor subfamily 2 group F member 1.	0.877
BCL11B	NR2F2	ENSPTRP00000052505	ENSPTRP00000078925	BAF chromatin remodeling complex subunit BCL11B.	Nuclear receptor subfamily 2, group F, member 2.	0.771
BCL11B	PAX6	ENSPTRP00000052505	ENSPTRP00000065705	BAF chromatin remodeling complex subunit BCL11B.	PAX6 isoform 13.	0.584
BCL11B	RBFOX3	ENSPTRP00000052505	ENSPTRP00000093937	BAF chromatin remodeling complex subunit BCL11B.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.478
BCL11B	SATB2	ENSPTRP00000052505	ENSPTRP00000080249	BAF chromatin remodeling complex subunit BCL11B.	DNA-binding protein SATB.	0.731
BCL11B	TBR1	ENSPTRP00000052505	ENSPTRP00000046292	BAF chromatin remodeling complex subunit BCL11B.	T-box brain transcription factor 1.	0.756
CUX2	BCL11B	ENSPTRP00000089985	ENSPTRP00000052505	Homeobox protein cut-like.	BAF chromatin remodeling complex subunit BCL11B.	0.516
CUX2	EMX1	ENSPTRP00000089985	ENSPTRP00000057829	Homeobox protein cut-like.	Empty spiracles homeobox 1.	0.469
CUX2	FEZF2	ENSPTRP00000089985	ENSPTRP00000079962	Homeobox protein cut-like.	FEZ family zinc finger 2.	0.604
CUX2	PAX6	ENSPTRP00000089985	ENSPTRP00000065705	Homeobox protein cut-like.	PAX6 isoform 13.	0.454
CUX2	SATB2	ENSPTRP00000089985	ENSPTRP00000080249	Homeobox protein cut-like.	DNA-binding protein SATB.	0.552
CUX2	TBR1	ENSPTRP00000089985	ENSPTRP00000046292	Homeobox protein cut-like.	T-box brain transcription factor 1.	0.498