STRINGSTRING
SKI SKI ZFYVE9 ZFYVE9 BMPR1A BMPR1A ACVRL1 ACVRL1 ACVR1B ACVR1B GDF11 GDF11 INHBC INHBC INHBE INHBE BMP4 BMP4 RNF111 RNF111 SMAD6 SMAD6 NOG NOG SMAD7 SMAD7 SMAD4 SMAD4 ACVR2A ACVR2A ACVR1C ACVR1C INHA INHA BMP2 BMP2 GDF5 GDF5 BMP7 BMP7 BMPR1B BMPR1B SMAD1 SMAD1 FST FST ZFYVE16 ZFYVE16 BMP6 BMP6 BMP5 BMP5 ENG ENG SMURF1 SMURF1 BMPR2 BMPR2 SMAD9 SMAD9 SMAD2 SMAD2 ENSPTRP00000064416 ENSPTRP00000064416 GDF2 GDF2 SKIL SKIL TGFBR1 TGFBR1 ACVR1 ACVR1 ACVR2B ACVR2B BMP10 BMP10 SMAD5 SMAD5 BMP4-2 BMP4-2 HJV HJV CHRD CHRD SMURF2 SMURF2 SMAD3 SMAD3 INHBB INHBB INHBA INHBA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
GDF11GDF11 isoform 1. (407 aa)
INHBCInhibin subunit beta C. (352 aa)
INHBEInhibin subunit beta E. (350 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
RNF111RNF111 isoform 5. (1003 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMAD7Mothers against decapentaplegic homolog. (491 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
GDF5GDF5 isoform 1. (501 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
FSTFST isoform 1. (344 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1539 aa)
BMP6Bone morphogenetic protein 6. (512 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
ENGENG isoform 1. (658 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ENSPTRP00000064416annotation not available (502 aa)
GDF2GDF2 isoform 1. (429 aa)
SKILSKI like proto-oncogene. (684 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
HJVHFE2 isoform 1. (426 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa)
SMURF2E3 ubiquitin-protein ligase. (744 aa)
SMAD3Mothers against decapentaplegic homolog. (442 aa)
INHBBInhibin subunit beta B. (407 aa)
INHBAInhibin subunit beta A. (426 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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