STRINGSTRING
HES3 HES3 ID3 ID3 RUNX3 RUNX3 FHL3 FHL3 SSBP3 SSBP3 LMO4 LMO4 BCL9 BCL9 PYGO2 PYGO2 LHX4 LHX4 CSRP1 CSRP1 BATF3 BATF3 LCOR LCOR IKZF5 IKZF5 CTBP2 CTBP2 LMO1 LMO1 MYOD1 MYOD1 BATF2 BATF2 BCL9L BCL9L ETV6 ETV6 TMTC1 TMTC1 IKZF4 IKZF4 NDFIP2 NDFIP2 BATF BATF TCF12 TCF12 TLE3 TLE3 ISL2 ISL2 ZNF423 ZNF423 ZFHX3 ZFHX3 ZFPM1 ZFPM1 NLK NLK TBX21 TBX21 KLF1 KLF1 ID2 ID2 TCF23 TCF23 TCF7L1 TCF7L1 ZNF217 ZNF217 ZNF35 ZNF35 KLF3 KLF3 CHIC2 CHIC2 ISL1 ISL1 ESM1 ESM1 SSBP2 SSBP2 IRF1 IRF1 HAND1 HAND1 EBF1 EBF1 TLX3 TLX3 IRF4 IRF4 BACH2 BACH2 PRDM1 PRDM1 MYB MYB IKZF1 IKZF1 LHX2 LHX2 FOXP3 FOXP3 MSC MSC LDB1 LDB1 TCF4 TCF4 ETS2 ETS2 FLI1 FLI1 MYOG MYOG ATCAY ATCAY TLE1 TLE1 TLE2 TLE2 NFATC2 NFATC2 RIPPLY1 RIPPLY1 RANBP17 RANBP17 PAX5 PAX5 RIPPLY2 RIPPLY2 IKZF3 IKZF3 ATOH1 ATOH1 GATA2 GATA2 LHX1 LHX1 FRMD3 FRMD3 ID1 ID1 CBFB CBFB ENSPTRP00000062206 ENSPTRP00000062206 OLIG1 OLIG1 FOXA1 FOXA1 ZEB1 ZEB1 FOXP4 FOXP4 LHX3 LHX3 TAL1 TAL1 GATA3 GATA3 ENSPTRP00000065187 ENSPTRP00000065187 ENSPTRP00000065870 ENSPTRP00000065870 CK820_G0026078 CK820_G0026078 TCF3 TCF3 MECOM MECOM OLIG2 OLIG2 CBFA2T3 CBFA2T3 TLE5 TLE5 LMO2 LMO2 FOXP2 FOXP2 ID4 ID4 TLE4 TLE4 ETV3 ETV3 SATB1 SATB1 LYL1 LYL1 EBF4 EBF4 RUNX1T1 RUNX1T1 MAF MAF LOC737148 LOC737148 HES6 HES6 IKZF2 IKZF2 TLE7 TLE7 CTBP1 CTBP1 ASCL1 ASCL1 CK820_G0051198 CK820_G0051198 LHX9 LHX9 LEF1 LEF1 EBF2 EBF2 LDB2 LDB2 TCF7 TCF7 TCF7L2 TCF7L2 NHLH1 NHLH1 ETV1-2 ETV1-2 RORC RORC SSBP4 SSBP4 SPI1 SPI1 ENSPTRP00000084126 ENSPTRP00000084126 LMO3 LMO3 PYGO1 PYGO1 ENSPTRP00000085013 ENSPTRP00000085013 ID1-2 ID1-2 ENSPTRP00000086171 ENSPTRP00000086171 IRF8 IRF8 GATA1 GATA1 FOXP4-2 FOXP4-2 ETS1 ETS1 ENSPTRP00000087502 ENSPTRP00000087502 EBF3 EBF3 LOC107969428 LOC107969428 KLF8 KLF8 CBFA2T2-2 CBFA2T2-2 FOXD1 FOXD1 RASEF RASEF RUNX1 RUNX1 ZEB2 ZEB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HES3HES3 isoform 1. (185 aa)
ID3Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein. (119 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
FHL3Four and a half LIM domains 3. (280 aa)
SSBP3Single stranded DNA binding protein 3. (388 aa)
LMO4LIM domain only 4. (165 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
PYGO2Pygopus family PHD finger 2. (405 aa)
LHX4LHX4 isoform 1. (390 aa)
CSRP1Cysteine and glycine-rich protein 1. (193 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (123 aa)
LCORLigand dependent nuclear receptor corepressor. (1556 aa)
IKZF5IKAROS family zinc finger 5 (Pegasus). (419 aa)
CTBP2CTBP2 isoform 10. (985 aa)
LMO1LIM domain only 1. (156 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (274 aa)
BCL9LB-cell CLL/lymphoma 9-like. (1499 aa)
ETV6ETV6 isoform 1. (452 aa)
TMTC1Transmembrane O-mannosyltransferase targeting cadherins 1. (944 aa)
IKZF4IKAROS family zinc finger 4. (585 aa)
NDFIP2Nedd4 family interacting protein 2. (336 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
TCF12Transcription factor 12. (706 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
ISL2ISL LIM homeobox 2. (359 aa)
ZNF423Zinc finger protein 423. (1284 aa)
ZFHX3Zinc finger homeobox 3. (3688 aa)
ZFPM1ZFPM1 isoform 1. (974 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
TBX21T-box transcription factor 21. (535 aa)
KLF1Kruppel like factor 1. (362 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
TCF23Transcription factor 23. (214 aa)
TCF7L1Transcription factor 7 like 1. (587 aa)
ZNF217Zinc finger protein 217. (1061 aa)
ZNF35Zinc finger protein 35. (527 aa)
KLF3Kruppel-like factor 3 (Basic). (345 aa)
CHIC2Cysteine-rich hydrophobic domain 2. (165 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ESM1Endothelial cell-specific molecule 1. (184 aa)
SSBP2Single stranded DNA binding protein 2. (369 aa)
IRF1Interferon regulatory factor. (325 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
EBF1EBF transcription factor 1. (591 aa)
TLX3TLX3 isoform 1. (291 aa)
IRF4Interferon regulatory factor 4. (451 aa)
BACH2BACH2 isoform 1. (973 aa)
PRDM1PR/SET domain 1. (825 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
LHX2LHX2 isoform 1. (406 aa)
FOXP3FOXP3 isoform 4. (456 aa)
MSCMSC isoform 1. (295 aa)
LDB1LIM domain binding 1. (411 aa)
TCF4Transcription factor 4. (773 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
MYOGMYOG isoform 1. (249 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (377 aa)
TLE1Transducin-like enhancer of split 1. (814 aa)
TLE2Transducin-like enhancer of split 2. (716 aa)
NFATC2NFATC2 isoform 4. (938 aa)
RIPPLY1Ripply transcriptional repressor 1. (151 aa)
RANBP17RAN binding protein 17. (1088 aa)
PAX5PAX5 isoform 1. (391 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
ATOH1Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). (356 aa)
GATA2GATA binding protein 2. (480 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
FRMD3FERM domain containing 3. (597 aa)
ID1Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (155 aa)
CBFBCore-binding factor, beta subunit. (182 aa)
ENSPTRP00000062206annotation not available (69 aa)
OLIG1OLIG1 isoform 2. (272 aa)
FOXA1FOXA1 isoform 1. (471 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
FOXP4FOXP4 isoform 3. (668 aa)
LHX3LHX3 isoform 2. (402 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
GATA3GATA binding protein 3. (444 aa)
ENSPTRP00000065187annotation not available (156 aa)
ENSPTRP00000065870annotation not available (412 aa)
CK820_G0026078SSBP4 isoform 2. (71 aa)
TCF3TCF3 isoform 3. (673 aa)
MECOMMDS1 and EVI1 complex locus. (1230 aa)
OLIG2OLIG2 isoform 1. (323 aa)
CBFA2T3CBFA2/RUNX1 translocation partner 3. (653 aa)
TLE5AES isoform 1. (203 aa)
LMO2LIM domain only 2. (228 aa)
FOXP2Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
ETV3ETS translocation variant 3; Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity (By similarity); Belongs to the ETS family. (512 aa)
SATB1DNA-binding protein SATB. (795 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
EBF4EBF4 isoform 5. (616 aa)
RUNX1T1RUNX1 translocation partner 1. (663 aa)
MAFMAF isoform 2; Belongs to the bZIP family. (402 aa)
LOC737148Single-stranded DNA-binding protein 3 pseudogene. (331 aa)
HES6Hes family bHLH transcription factor 6. (224 aa)
IKZF2IKAROS family zinc finger 2 (Helios). (532 aa)
TLE7TLE family member 7. (441 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
CK820_G0051198TLE2 isoform 3. (113 aa)
LHX9LHX9 isoform 2. (397 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
EBF2EBF transcription factor 2. (575 aa)
LDB2LIM domain binding 2. (373 aa)
TCF7Transcription factor 7. (481 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
ETV1-2ETS variant 1. (506 aa)
RORCRAR related orphan receptor C. (525 aa)
SSBP4SSBP4 isoform 11. (54 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
ENSPTRP00000084126annotation not available (117 aa)
LMO3LIM domain only 3. (177 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
ENSPTRP00000085013annotation not available (166 aa)
ID1-2Inhibitor of DNA binding 1, HLH protein. (155 aa)
ENSPTRP00000086171annotation not available (421 aa)
IRF8Interferon regulatory factor 8. (426 aa)
GATA1GATA binding protein 1. (413 aa)
FOXP4-2Forkhead box P4. (668 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
ENSPTRP00000087502annotation not available (347 aa)
EBF3EBF transcription factor 3. (621 aa)
LOC107969428Single stranded DNA binding protein 4. (395 aa)
KLF8Kruppel-like factor 8. (359 aa)
CBFA2T2-2CBFA2/RUNX1 partner transcriptional co-repressor 2. (614 aa)
FOXD1FOXD1 isoform 1. (439 aa)
RASEFRAS and EF-hand domain containing. (740 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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