(65 nodes) Mixed, incl. Chaperonin-containing T-complex, and Prefoldin complex network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STRIP1	Family with sequence similarity 40, member A. (877 aa)
	CTTNBP2NL	CTTNBP2 N-terminal like. (639 aa)
	SIKE1	Suppressor of IKBKE 1. (211 aa)
	PFDN2	Prefoldin subunit 2. (154 aa)
	FGFR1OP2	FGFR1 oncogene partner 2. (253 aa)
	PFDN5	Prefoldin subunit 5. (154 aa)
	BBS10	Bardet-Biedl syndrome 10. (723 aa)
	STRN	Striatin, calmodulin binding protein. (780 aa)
	CCT4	T-complex protein 1 subunit delta. (544 aa)
	CCT7	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
	TXNDC9	Thioredoxin domain containing 9. (226 aa)
	MOB4	MOB1, Mps One Binder kinase activator-like 3. (225 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	PDCD10	Programmed cell death 10. (212 aa)
	BBS12	BBS12 isoform 1. (710 aa)
	CCT5	Chaperonin containing TCP1, subunit 5 (Epsilon). (541 aa)
	PFDN1	Prefoldin subunit 1. (122 aa)
	PFDN6	Prefoldin subunit 6. (129 aa)
	TCP1	T-complex protein 1 subunit alpha. (556 aa)
	CTTNBP2	Cortactin binding protein 2. (1665 aa)
	STRIP2	Striatin interacting protein 2. (834 aa)
	PDCL	PDCL isoform 1. (301 aa)
	STK26	Serine/threonine kinase 26. (438 aa)
	VBP1	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
	STRN3	Striatin, calmodulin binding protein 3. (797 aa)
	STK25	Serine/threonine kinase 25. (426 aa)
	CCT8L2	LOW QUALITY PROTEIN: putative T-complex protein 1 subunit theta-like 1. (557 aa)
	CCT3	T-complex protein 1 subunit gamma. (545 aa)
	STK24	Serine/threonine kinase 24. (443 aa)
	CCT6A	Chaperonin containing TCP1, subunit 6A (Zeta 1). (564 aa)
	ENSPTRP00000061551	annotation not available (394 aa)
	PFDN5-2	Prefoldin subunit 5. (127 aa)
	ENSPTRP00000064921	annotation not available (544 aa)
	ENSPTRP00000068859	annotation not available (227 aa)
	LOC101058414	Thioredoxin domain-containing protein 9 pseudogene. (188 aa)
	SLMAP	Sarcolemma associated protein. (828 aa)
	ENSPTRP00000073653	annotation not available (190 aa)
	LOC100614251	F-box/WD repeat-containing protein 4 pseudogene. (342 aa)
	ENSPTRP00000074536	annotation not available (520 aa)
	VBP1-2	Prefoldin subunit 3. (233 aa)
	ENSPTRP00000075146	annotation not available (457 aa)
	CCT2	Chaperonin containing TCP1, subunit 2 (Beta). (535 aa)
	CK820_G0014764	MOB4 isoform 7. (206 aa)
	MAP4K2	Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (837 aa)
	LOC743586	T-complex protein 1 subunit alpha pseudogene. (338 aa)
	CCT6B	Chaperonin containing TCP1 subunit 6B. (553 aa)
	ENSPTRP00000077287	annotation not available (417 aa)
	FBXW4	F-box and WD repeat domain containing 4. (412 aa)
	TRAF3IP3	TRAF3 interacting protein 3. (551 aa)
	LOC470874	Phosducin-like protein 3 pseudogene. (191 aa)
	PDCL3	Phosducin-like 3. (239 aa)
	ENSPTRP00000083011	annotation not available (70 aa)
	STRN4	Striatin, calmodulin binding protein 4. (760 aa)
	LOC735923	Phosducin-like protein 3 pseudogene. (220 aa)
	STK26-2	Serine/threonine protein kinase MST4. (416 aa)
	PFDN4	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
	ENSPTRP00000087977	annotation not available (564 aa)
	ENSPTRP00000088042	annotation not available (103 aa)
	ENSPTRP00000088116	annotation not available (384 aa)
	STRIP2-2	Striatin interacting protein 2. (834 aa)
	ENSPTRP00000092193	annotation not available (506 aa)
	CCT8	Chaperonin containing TCP1, subunit 8 (Theta). (548 aa)
	CCT8L2-2	T-complex protein 1 subunit theta-like 2. (557 aa)
	ENSPTRP00000093266	annotation not available (417 aa)
	LOC107971862	Putative T-complex protein 1 subunit theta-like 1. (447 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS10	BBS12	ENSPTRP00000008903	ENSPTRP00000028195	Bardet-Biedl syndrome 10.	BBS12 isoform 1.	0.993
BBS10	CCT2	ENSPTRP00000008903	ENSPTRP00000076372	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1, subunit 2 (Beta).	0.993
BBS10	CCT3	ENSPTRP00000008903	ENSPTRP00000051719	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit gamma.	0.938
BBS10	CCT4	ENSPTRP00000008903	ENSPTRP00000020548	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit delta.	0.922
BBS10	CCT5	ENSPTRP00000008903	ENSPTRP00000028695	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1, subunit 5 (Epsilon).	0.972
BBS10	CCT6A	ENSPTRP00000008903	ENSPTRP00000061456	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1, subunit 6A (Zeta 1).	0.814
BBS10	CCT6B	ENSPTRP00000008903	ENSPTRP00000077284	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1 subunit 6B.	0.769
BBS10	CCT7	ENSPTRP00000008903	ENSPTRP00000020696	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.929
BBS10	CCT8	ENSPTRP00000008903	ENSPTRP00000092452	Bardet-Biedl syndrome 10.	Chaperonin containing TCP1, subunit 8 (Theta).	0.956
BBS10	CCT8L2	ENSPTRP00000008903	ENSPTRP00000049878	Bardet-Biedl syndrome 10.	LOW QUALITY PROTEIN: putative T-complex protein 1 subunit theta-like 1.	0.931
BBS10	CCT8L2-2	ENSPTRP00000008903	ENSPTRP00000092933	Bardet-Biedl syndrome 10.	T-complex protein 1 subunit theta-like 2.	0.931
BBS10	ENSPTRP00000061551	ENSPTRP00000008903	ENSPTRP00000061551	Bardet-Biedl syndrome 10.	annotation not available	0.922
BBS10	ENSPTRP00000064921	ENSPTRP00000008903	ENSPTRP00000064921	Bardet-Biedl syndrome 10.	annotation not available	0.913
BBS10	ENSPTRP00000074536	ENSPTRP00000008903	ENSPTRP00000074536	Bardet-Biedl syndrome 10.	annotation not available	0.814
BBS10	ENSPTRP00000075146	ENSPTRP00000008903	ENSPTRP00000075146	Bardet-Biedl syndrome 10.	annotation not available	0.921
BBS10	ENSPTRP00000077287	ENSPTRP00000008903	ENSPTRP00000077287	Bardet-Biedl syndrome 10.	annotation not available	0.674
BBS10	ENSPTRP00000087977	ENSPTRP00000008903	ENSPTRP00000087977	Bardet-Biedl syndrome 10.	annotation not available	0.814
BBS10	ENSPTRP00000088042	ENSPTRP00000008903	ENSPTRP00000088042	Bardet-Biedl syndrome 10.	annotation not available	0.411
BBS10	ENSPTRP00000092193	ENSPTRP00000008903	ENSPTRP00000092193	Bardet-Biedl syndrome 10.	annotation not available	0.814
BBS10	ENSPTRP00000093266	ENSPTRP00000008903	ENSPTRP00000093266	Bardet-Biedl syndrome 10.	annotation not available	0.674