(45 nodes) Zinc ion homeostasis, and Zinc ion transport network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ECM1	Extracellular matrix protein 1. (540 aa)
	ROBO3	ROBO3 isoform 3. (1384 aa)
	KRT4	KRT4 isoform 1; Belongs to the intermediate filament family. (608 aa)
	SLC39A9	Solute carrier family 39 (Zinc transporter), member 9. (307 aa)
	SLC30A4	Solute carrier family 30 (Zinc transporter), member 4. (429 aa)
	MT4	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
	MT3	MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	MT1F	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	LOC467981	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	MT1A	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	MT1X	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	KRT13	KRT13 isoform 5; Belongs to the intermediate filament family. (458 aa)
	SLC39A11	Solute carrier family 39 (Metal ion transporter), member 11. (342 aa)
	SLC39A3	T0181386 isoform 1. (323 aa)
	CEACAM1	CEACAM1 isoform 3. (518 aa)
	SLC15A2	Solute carrier family 15 member 2. (729 aa)
	MT2A	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	SLC39A7	SLC39A7 isoform 2. (469 aa)
	KCNV2	Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (545 aa)
	MTF1	Metal regulatory transcription factor 1. (753 aa)
	SLC39A8	Solute carrier family 39 (Zinc transporter), member 8. (460 aa)
	CLEC17A	CLEC17A isoform 3. (381 aa)
	SLC30A5	Solute carrier family 30 (Zinc transporter), member 5. (765 aa)
	S100Z	Protein S100; Belongs to the S-100 family. (98 aa)
	SLC39A12	Solute carrier family 39 member 12. (691 aa)
	SLC30A2	SLC30A2 isoform 2. (372 aa)
	MT1E	MT1E isoform 3; Belongs to the metallothionein superfamily. Type 1 family. (126 aa)
	ZSWIM8	ZSWIM8 isoform 6. (1900 aa)
	MT1H-2	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	ENSPTRP00000061305	annotation not available (112 aa)
	SLC39A14	SLC39A14 isoform 1. (490 aa)
	MT1M	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (69 aa)
	NELL2	Neural EGFL like 2. (839 aa)
	ENSPTRP00000067501	annotation not available (169 aa)
	SLC39A13	Solute carrier family 39 (Zinc transporter), member 13. (364 aa)
	ZNF823	Zinc finger protein 823. (612 aa)
	LOC101058101	Metallothionein 1/2. (52 aa)
	ENSPTRP00000074383	annotation not available (55 aa)
	SLC30A7	Solute carrier family 30 (Zinc transporter), member 7. (376 aa)
	ENSPTRP00000077750	annotation not available (630 aa)
	MT1L	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (79 aa)
	CALU	CALU isoform 5. (323 aa)
	MT1HL1	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	ZBTB44	ZBTB44 isoform 3. (580 aa)
	SLC30A6	Solute carrier family 30 member 6. (501 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALU	KCNV2	ENSPTRP00000083567	ENSPTRP00000035472	CALU isoform 5.	Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family.	0.745
CALU	NELL2	ENSPTRP00000083567	ENSPTRP00000067108	CALU isoform 5.	Neural EGFL like 2.	0.581
CALU	S100Z	ENSPTRP00000083567	ENSPTRP00000048303	CALU isoform 5.	Protein S100; Belongs to the S-100 family.	0.885
CALU	SLC39A14	ENSPTRP00000083567	ENSPTRP00000064152	CALU isoform 5.	SLC39A14 isoform 1.	0.885
CEACAM1	CLEC17A	ENSPTRP00000018992	ENSPTRP00000044165	CEACAM1 isoform 3.	CLEC17A isoform 3.	0.736
CEACAM1	ECM1	ENSPTRP00000018992	ENSPTRP00000002133	CEACAM1 isoform 3.	Extracellular matrix protein 1.	0.744
CEACAM1	SLC15A2	ENSPTRP00000018992	ENSPTRP00000026349	CEACAM1 isoform 3.	Solute carrier family 15 member 2.	0.787
CEACAM1	SLC39A13	ENSPTRP00000018992	ENSPTRP00000067680	CEACAM1 isoform 3.	Solute carrier family 39 (Zinc transporter), member 13.	0.781
CEACAM1	ZBTB44	ENSPTRP00000018992	ENSPTRP00000086820	CEACAM1 isoform 3.	ZBTB44 isoform 3.	0.739
CEACAM1	ZSWIM8	ENSPTRP00000018992	ENSPTRP00000056825	CEACAM1 isoform 3.	ZSWIM8 isoform 6.	0.778
CLEC17A	CEACAM1	ENSPTRP00000044165	ENSPTRP00000018992	CLEC17A isoform 3.	CEACAM1 isoform 3.	0.736
CLEC17A	ECM1	ENSPTRP00000044165	ENSPTRP00000002133	CLEC17A isoform 3.	Extracellular matrix protein 1.	0.788
CLEC17A	SLC15A2	ENSPTRP00000044165	ENSPTRP00000026349	CLEC17A isoform 3.	Solute carrier family 15 member 2.	0.813
CLEC17A	SLC39A13	ENSPTRP00000044165	ENSPTRP00000067680	CLEC17A isoform 3.	Solute carrier family 39 (Zinc transporter), member 13.	0.812
CLEC17A	ZBTB44	ENSPTRP00000044165	ENSPTRP00000086820	CLEC17A isoform 3.	ZBTB44 isoform 3.	0.761
CLEC17A	ZSWIM8	ENSPTRP00000044165	ENSPTRP00000056825	CLEC17A isoform 3.	ZSWIM8 isoform 6.	0.812
ECM1	CEACAM1	ENSPTRP00000002133	ENSPTRP00000018992	Extracellular matrix protein 1.	CEACAM1 isoform 3.	0.744
ECM1	CLEC17A	ENSPTRP00000002133	ENSPTRP00000044165	Extracellular matrix protein 1.	CLEC17A isoform 3.	0.788
ECM1	SLC15A2	ENSPTRP00000002133	ENSPTRP00000026349	Extracellular matrix protein 1.	Solute carrier family 15 member 2.	0.820
ECM1	SLC39A13	ENSPTRP00000002133	ENSPTRP00000067680	Extracellular matrix protein 1.	Solute carrier family 39 (Zinc transporter), member 13.	0.830