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PSMB2 PSMB2 PSMB4 PSMB4 PSMA1 PSMA1 PSMA6 PSMA6 PSMA3 PSMA3 PSMA4 PSMA4 PSMD7 PSMD7 PSMD11 PSMD11 PSMD3 PSMD3 PSMA8 PSMA8 PSMD14 PSMD14 PSMD1 PSMD1 PSMA7 PSMA7 PSMD6 PSMD6 PSMD2 PSMD2 PSMB9 PSMB9 PSMB1 PSMB1 PSMC2 PSMC2 PSMB7 PSMB7 PSMA2 PSMA2 USP14 USP14 PSMC5 PSMC5 ENSPTRP00000064540 ENSPTRP00000064540 ENSPTRP00000065241 ENSPTRP00000065241 PSMB6 PSMB6 PSMB3 PSMB3 PSMD13 PSMD13 ENSPTRP00000076582 ENSPTRP00000076582 PSMD12 PSMD12 PSMA5 PSMA5 ENSPTRP00000086535 ENSPTRP00000086535 PSMC4 PSMC4 PSMB5 PSMB5 PSMC6 PSMC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB2Proteasome subunit beta. (201 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA4Proteasome subunit alpha type-4 isoform X2. (261 aa)
PSMD7Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa)
PSMD11Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11. (422 aa)
PSMD3Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3. (534 aa)
PSMA8Proteasome subunit alpha type. (256 aa)
PSMD14Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD6Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6. (441 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB9Proteasome subunit beta. (218 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMC2Proteasome (Prosome, macropain) 26S subunit, ATPase, 2; Belongs to the AAA ATPase family. (433 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
USP14Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...] (493 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (406 aa)
ENSPTRP00000064540annotation not available (358 aa)
ENSPTRP00000065241annotation not available (350 aa)
PSMB6Proteasome subunit beta. (244 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD13Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13. (399 aa)
ENSPTRP00000076582annotation not available (377 aa)
PSMD12Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSPTRP00000086535annotation not available (351 aa)
PSMC4Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family. (421 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (411 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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