STRINGSTRING
PHF20 PHF20 CK820_G0037203 CK820_G0037203 MRGBP MRGBP EP300 EP300 TADA3 TADA3 KAT2B KAT2B MSL2 MSL2 YEATS2 YEATS2 TADA2B TADA2B ENSPTRP00000076134 ENSPTRP00000076134 ZZZ3 ZZZ3 TAF5L TAF5L MORF4L1 MORF4L1 CREBBP CREBBP ENSPTRP00000074641 ENSPTRP00000074641 POLE3 POLE3 ENSPTRP00000037477 ENSPTRP00000037477 TAF12 TAF12 DR1 DR1 VPS72 VPS72 EPC1 EPC1 KANSL1-2 KANSL1-2 BRD1 BRD1 ENSPTRP00000088036 ENSPTRP00000088036 ENY2 ENY2 SUPT3H SUPT3H ENSPTRP00000087807 ENSPTRP00000087807 MBTD1 MBTD1 BRD8 BRD8 SF3B5 SF3B5 ACTL6B ACTL6B ING3 ING3 KAT6A KAT6A ATXN7 ATXN7 ING3-2 ING3-2 TAF9 TAF9 JADE2 JADE2 KANSL2 KANSL2 LOC100610514 LOC100610514 PHF14 PHF14 RUVBL2 RUVBL2 ENSPTRP00000064849 ENSPTRP00000064849 ACTL6B-2 ACTL6B-2 TAF5 TAF5 KAT6B KAT6B KAT5 KAT5 ATF2 ATF2 TAF6 TAF6 TAF6L TAF6L BRPF3 BRPF3 MLLT3 MLLT3 KANSL1L KANSL1L KAT8 KAT8 TAF10 TAF10 TAF4 TAF4 ACTB ACTB MAP3K7 MAP3K7 TAF2 TAF2 RUVBL1 RUVBL1 TAF9B TAF9B DMAP1 DMAP1 TRRAP TRRAP SUPT7L SUPT7L EP400 EP400 BRPF1 BRPF1 CK820_G0021068 CK820_G0021068 HCFC1 HCFC1 MSL3 MSL3 ENSPTRP00000072986 ENSPTRP00000072986 ACTL6A ACTL6A WDR5 WDR5 LOC461609 LOC461609 SUPT20H SUPT20H ENSPTRP00000070717 ENSPTRP00000070717 ING5 ING5 ATXN7L3 ATXN7L3 ENSPTRP00000069606 ENSPTRP00000069606 ENSPTRP00000069337 ENSPTRP00000069337 PHF20L1 PHF20L1 PHF20-2 PHF20-2 JADE1 JADE1 OGT OGT TADA1 TADA1 ENSPTRP00000066334 ENSPTRP00000066334 MEAF6 MEAF6 MCRS1 MCRS1 SUPT20HL2 SUPT20HL2 TEX30 TEX30 HCFC1-2 HCFC1-2 JADE3 JADE3 ING4 ING4 YEATS4 YEATS4 ENSPTRP00000009603 ENSPTRP00000009603 MBIP MBIP SGF29 SGF29 SF3B3 SF3B3 USP22 USP22 TADA2A TADA2A MSL1 MSL1 KAT2A KAT2A KANSL1 KANSL1 KAT7 KAT7 MLLT1 MLLT1 POLE4 POLE4 KANSL3 KANSL3 EPC2 EPC2 KAT14 KAT14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHF20PHD finger protein 20. (1012 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
MRGBPChromosome 20 open reading frame 20. (204 aa)
EP300E1A binding protein p300. (2175 aa)
TADA3Transcriptional adaptor 3. (432 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
MSL2Male-specific lethal 2 homolog. (577 aa)
YEATS2YEATS domain containing 2. (1416 aa)
TADA2BTranscriptional adapter. (420 aa)
ENSPTRP00000076134annotation not available (211 aa)
ZZZ3Zinc finger, ZZ-type containing 3. (903 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (589 aa)
MORF4L1Mortality factor 4 like 1. (363 aa)
CREBBPCREB binding protein. (2442 aa)
ENSPTRP00000074641annotation not available (485 aa)
POLE3Polymerase (DNA directed), epsilon 3 (P17 subunit). (147 aa)
ENSPTRP00000037477Jade family PHD finger 3. (279 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
DR1Down-regulator of transcription 1, TBP-binding (Negative cofactor 2). (176 aa)
VPS72Vacuolar protein sorting 72 homolog. (375 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
KANSL1-2KAT8 regulatory NSL complex subunit 1. (1105 aa)
BRD1Bromodomain containing 1. (1189 aa)
ENSPTRP00000088036annotation not available (243 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (100 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (424 aa)
ENSPTRP00000087807annotation not available (481 aa)
MBTD1Mbt domain containing 1. (630 aa)
BRD8Bromodomain containing 8. (1235 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
ACTL6BACTL6B isoform 1; Belongs to the actin family. (426 aa)
ING3Inhibitor of growth protein. (418 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa)
ATXN7ATXN7 isoform 2. (939 aa)
ING3-2Inhibitor of growth family member 3. (418 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
JADE2Jade family PHD finger 2. (834 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (675 aa)
LOC100610514Transcription factor SPT20 homolog-like 1. (821 aa)
PHF14PHD finger protein 14. (948 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ENSPTRP00000064849annotation not available (150 aa)
ACTL6B-2Actin like 6B. (426 aa)
TAF5TATA-box binding protein associated factor 5. (803 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2070 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (603 aa)
BRPF3Bromodomain and PHD finger containing, 3. (1205 aa)
MLLT3MLLT3 isoform 1. (570 aa)
KANSL1LKAT8 regulatory NSL complex subunit 1 like. (987 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
TAF9BTAF9B isoform 1. (251 aa)
DMAP1DNA methyltransferase 1-associated protein 1. (467 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (414 aa)
EP400EP400 isoform 1. (3130 aa)
BRPF1Bromodomain and PHD finger containing, 1. (1253 aa)
CK820_G0021068Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
HCFC1Host cell factor C1. (2080 aa)
MSL3Male-specific lethal 3 homolog. (521 aa)
ENSPTRP00000072986annotation not available (244 aa)
ACTL6AACTL6A isoform 2; Belongs to the actin family. (430 aa)
WDR5WD repeat domain 5. (334 aa)
LOC461609Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] (323 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
ENSPTRP00000070717annotation not available (287 aa)
ING5Inhibitor of growth family member 5. (254 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
ENSPTRP00000069606LOW QUALITY PROTEIN: putative male-specific lethal-3 protein-like 2. (481 aa)
ENSPTRP00000069337annotation not available (165 aa)
PHF20L1PHD finger protein 20-like 1. (1022 aa)
PHF20-2PHD finger protein 20. (103 aa)
JADE1Jade family PHD finger 1. (842 aa)
OGTOGT isoform 6. (1057 aa)
TADA1Transcriptional adaptor 1. (335 aa)
ENSPTRP00000066334annotation not available (316 aa)
MEAF6MYST/Esa1 associated factor 6. (201 aa)
MCRS1Microspherule protein 1. (475 aa)
SUPT20HL2Putative transcription factor SPT20 homolog-like 2. (786 aa)
TEX30Chromosome 13 open reading frame 27. (227 aa)
HCFC1-2HCFC1 isoform 1. (2035 aa)
JADE3PHD finger protein 16. (823 aa)
ING4Inhibitor of growth protein. (249 aa)
YEATS4YEATS domain containing 4. (227 aa)
ENSPTRP00000009603annotation not available (419 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
SGF29SGF29 isoform 6. (265 aa)
SF3B3Splicing factor 3b, subunit 3, 130kDa. (1217 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
TADA2ATranscriptional adapter. (443 aa)
MSL1MSL complex subunit 1. (614 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (1105 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
MLLT1Myeloid/lymphoid or mixed-lineage leukemia translocated to, 1. (559 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (116 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (878 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
KAT14Lysine acetyltransferase 14. (782 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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