47 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOL9	Serine palmitoyltransferase, long chain base subunit 2. (702 aa)
	ERI3	ERI1 exoribonuclease family member 3. (337 aa)
	RPP40	Ribonuclease P/MRP 40kDa subunit. (363 aa)
	ENSPTRP00000090652	annotation not available (159 aa)
	ENSPTRP00000073278	annotation not available (225 aa)
	ENSPTRP00000073967	annotation not available (183 aa)
	EXOSC2-2	Exosome component 2. (293 aa)
	MTREX	Superkiller viralicidic activity 2-like 2. (1042 aa)
	NOP14	NOP14 nucleolar protein homolog. (837 aa)
	EXOSC7	Exosome component 7. (291 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (588 aa)
	URB1	URB1 ribosome biogenesis 1 homolog. (2271 aa)
	LOC458388	RPS21 isoform 1. (83 aa)
	C1D	C1D nuclear receptor corepressor. (180 aa)
	ENSPTRP00000068258	annotation not available (251 aa)
	ENSPTRP00000064723	annotation not available (234 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
	ERI2	ERI1 exoribonuclease family member 2. (598 aa)
	NOP9	NOP9 isoform 1. (634 aa)
	EXOSC8	Exosome component 8. (276 aa)
	RRS1	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
	PRKDC	Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa)
	EXOSC2	Exosome component 2. (293 aa)
	MPHOSPH6	M-phase phosphoprotein 6. (160 aa)
	ENSPTRP00000077966	annotation not available (76 aa)
	LOC473170	Pescadillo homolog pseudogene. (488 aa)
	ERI1	Exoribonuclease 1. (271 aa)
	EXOSC4	Exosome component 4. (245 aa)
	MAK16	Protein MAK16 homolog; Belongs to the MAK16 family. (301 aa)
	ABT1	Activator of basal transcription 1. (272 aa)
	KRI1	KRI1 isoform 1. (705 aa)
	ENSPTRP00000082131	annotation not available (249 aa)
	EXOSC9	Exosome component 9. (456 aa)
	EXOSC10	EXOSC10 isoform 1. (869 aa)
	NSA2	TGF-beta-inducible nuclear protein 1. (261 aa)
	RRP15	Ribosomal RNA processing 15 homolog. (285 aa)
	RPF1	Ribosome production factor 1 homolog. (349 aa)
	FCF1	FCF1 small subunit (SSU) processome component homolog. (198 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (847 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (433 aa)
	UTP20	UTP20, small subunit (SSU) processome component, homolog. (2785 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (746 aa)
	RCL1	RCL1 isoform 3. (373 aa)
	EXOSC3	Exosome complex exonuclease RRP40. (275 aa)
	LAS1L	LAS1 like, ribosome biogenesis factor. (735 aa)
	RPS21	RPS21 isoform 5. (90 aa)
	CK820_G0002899	FCF1 isoform 3. (66 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABT1	FTSJ3	ENSPTRP00000030427	ENSPTRP00000016175	Activator of basal transcription 1.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.712
ABT1	KRI1	ENSPTRP00000030427	ENSPTRP00000077990	Activator of basal transcription 1.	KRI1 isoform 1.	0.606
ABT1	MAK16	ENSPTRP00000030427	ENSPTRP00000034497	Activator of basal transcription 1.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.674
ABT1	NOP14	ENSPTRP00000030427	ENSPTRP00000027308	Activator of basal transcription 1.	NOP14 nucleolar protein homolog.	0.912
ABT1	RPF1	ENSPTRP00000030427	ENSPTRP00000001557	Activator of basal transcription 1.	Ribosome production factor 1 homolog.	0.563
ABT1	RRS1	ENSPTRP00000030427	ENSPTRP00000053146	Activator of basal transcription 1.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.659
BOP1	EIF6	ENSPTRP00000035390	ENSPTRP00000023044	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.948
BOP1	ENSPTRP00000064723	ENSPTRP00000035390	ENSPTRP00000064723	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	annotation not available	0.898
BOP1	ENSPTRP00000068258	ENSPTRP00000035390	ENSPTRP00000068258	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	annotation not available	0.898
BOP1	ENSPTRP00000073278	ENSPTRP00000035390	ENSPTRP00000073278	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	annotation not available	0.898
BOP1	ENSPTRP00000082131	ENSPTRP00000035390	ENSPTRP00000082131	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	annotation not available	0.898
BOP1	ENSPTRP00000090652	ENSPTRP00000035390	ENSPTRP00000090652	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	annotation not available	0.898
BOP1	EXOSC10	ENSPTRP00000035390	ENSPTRP00000062272	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EXOSC10 isoform 1.	0.454
BOP1	FTSJ3	ENSPTRP00000035390	ENSPTRP00000016175	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.989
BOP1	KRI1	ENSPTRP00000035390	ENSPTRP00000077990	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	KRI1 isoform 1.	0.772
BOP1	LAS1L	ENSPTRP00000035390	ENSPTRP00000037752	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	LAS1 like, ribosome biogenesis factor.	0.843
BOP1	LOC473170	ENSPTRP00000035390	ENSPTRP00000092716	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog pseudogene.	0.996
BOP1	MAK16	ENSPTRP00000035390	ENSPTRP00000034497	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.951
BOP1	MTREX	ENSPTRP00000035390	ENSPTRP00000028912	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Superkiller viralicidic activity 2-like 2.	0.858
BOP1	NOL9	ENSPTRP00000035390	ENSPTRP00000000173	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Serine palmitoyltransferase, long chain base subunit 2.	0.813