50 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GDF3	Growth differentiation factor 3. (364 aa)
	TDRD5	Tudor domain containing 5. (1035 aa)
	TDRD1	Tudor domain containing 1. (1189 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (521 aa)
	ENSPTRP00000089747	annotation not available (156 aa)
	ENSPTRP00000088702	annotation not available (170 aa)
	WT1	WT1 transcription factor. (514 aa)
	PTCH1	PTCH1 isoform 8. (1428 aa)
	TDRD6	Tudor domain containing 6. (2097 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	STIL	STIL centriolar assembly protein. (1288 aa)
	TMED2	Transmembrane emp24 domain trafficking protein 2. (208 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1333 aa)
	CHRDL1	CHRDL1 isoform 3. (458 aa)
	CK820_G0021556	TMED2 isoform 3. (200 aa)
	ENSPTRP00000076822	annotation not available (142 aa)
	TDRD10	Tudor domain containing 10. (366 aa)
	DCANP1	LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
	MTHFSD	Methenyltetrahydrofolate synthetase domain containing. (383 aa)
	KDM6A	KDM6A isoform 1. (1453 aa)
	TIFAB	TIFAB isoform 1. (161 aa)
	BASP1	Brain abundant, membrane attached signal protein 1. (226 aa)
	PLD6	Phospholipase D family member 6. (252 aa)
	TDRKH	Tudor and KH domain containing. (605 aa)
	WNT7A	Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
	C2CD3	C2CD3 isoform 3. (2298 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ENSPTRP00000062011	annotation not available (389 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (733 aa)
	CXXC4	CXXC4 isoform 2. (366 aa)
	LHX1	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
	RIPPLY2	Ripply transcriptional repressor 2. (128 aa)
	RIPPLY1	Ripply transcriptional repressor 1. (151 aa)
	TDRD7	Tudor domain containing 7. (1098 aa)
	PCSK6	PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	TDRD15	Tudor domain containing 15. (1934 aa)
	TASOR	Transcription activation suppressor. (1609 aa)
	TBXT	T-box transcription factor T. (435 aa)
	NEUROG1	NEUROG1 isoform 1. (237 aa)
	TDGF1	Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	TBX6	T-box transcription factor 6. (443 aa)
	MESP2	Mesoderm posterior bHLH transcription factor 2. (389 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	SMAD6	Mothers against decapentaplegic homolog. (496 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BASP1	WT1	ENSPTRP00000067678	ENSPTRP00000087673	Brain abundant, membrane attached signal protein 1.	WT1 transcription factor.	0.615
CTNNB1	CXXC4	ENSPTRP00000044466	ENSPTRP00000055473	Catenin (Cadherin-associated protein), beta 1, 88kDa.	CXXC4 isoform 2.	0.405
CTNNB1	FZD5	ENSPTRP00000044466	ENSPTRP00000021982	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.656
CTNNB1	PTCH1	ENSPTRP00000044466	ENSPTRP00000087586	Catenin (Cadherin-associated protein), beta 1, 88kDa.	PTCH1 isoform 8.	0.568
CTNNB1	SMAD2	ENSPTRP00000044466	ENSPTRP00000062376	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Mothers against decapentaplegic homolog.	0.938
CTNNB1	SMAD4	ENSPTRP00000044466	ENSPTRP00000017047	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Mothers against decapentaplegic homolog.	0.898
CTNNB1	SMAD6	ENSPTRP00000044466	ENSPTRP00000012318	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Mothers against decapentaplegic homolog.	0.405
CTNNB1	TBX6	ENSPTRP00000044466	ENSPTRP00000013650	Catenin (Cadherin-associated protein), beta 1, 88kDa.	T-box transcription factor 6.	0.421
CTNNB1	WNT1	ENSPTRP00000044466	ENSPTRP00000008364	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.846
CTNNB1	WNT5A	ENSPTRP00000044466	ENSPTRP00000086163	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.746
CTNNB1	WNT7A	ENSPTRP00000044466	ENSPTRP00000064840	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...]	0.669
CTNNB1	WT1	ENSPTRP00000044466	ENSPTRP00000087673	Catenin (Cadherin-associated protein), beta 1, 88kDa.	WT1 transcription factor.	0.497
CXXC4	CTNNB1	ENSPTRP00000055473	ENSPTRP00000044466	CXXC4 isoform 2.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.405
CXXC4	WT1	ENSPTRP00000055473	ENSPTRP00000087673	CXXC4 isoform 2.	WT1 transcription factor.	0.433
ENSPTRP00000062011	RIPPLY1	ENSPTRP00000062011	ENSPTRP00000047318	annotation not available	Ripply transcriptional repressor 1.	0.416
ENSPTRP00000062011	RIPPLY2	ENSPTRP00000062011	ENSPTRP00000049883	annotation not available	Ripply transcriptional repressor 2.	0.541
ENSPTRP00000062011	TBX6	ENSPTRP00000062011	ENSPTRP00000013650	annotation not available	T-box transcription factor 6.	0.817
ENSPTRP00000076822	GDF3	ENSPTRP00000076822	ENSPTRP00000007883	annotation not available	Growth differentiation factor 3.	0.672
ENSPTRP00000076822	SMAD2	ENSPTRP00000076822	ENSPTRP00000062376	annotation not available	Mothers against decapentaplegic homolog.	0.550
ENSPTRP00000088702	GDF3	ENSPTRP00000088702	ENSPTRP00000007883	annotation not available	Growth differentiation factor 3.	0.672