STRINGSTRING
NUDCD2 NUDCD2 ENSPTRP00000029492 ENSPTRP00000029492 CCNB1 CCNB1 PLK2 PLK2 PLK4 PLK4 MAD2L1 MAD2L1 ALPK1 ALPK1 BOD1L1 BOD1L1 TACC3 TACC3 CEP19 CEP19 CEP63 CEP63 TOPBP1 TOPBP1 POC1A POC1A DYNC1LI1 DYNC1LI1 SGO1 SGO1 AURKA AURKA FAM83D FAM83D TPX2 TPX2 FAM110A FAM110A CUL3 CUL3 DCTN1 DCTN1 SPAST SPAST YPEL5 YPEL5 AURKC AURKC CCDC155 CCDC155 CALM3 CALM3 WDR62 WDR62 CEP89 CEP89 HAUS8 HAUS8 MISP MISP CTDP1 CTDP1 HAUS1 HAUS1 CEP95 CEP95 EFCAB3 EFCAB3 TUBG1 TUBG1 CDC6 CDC6 RSKR RSKR SPAG5 SPAG5 UNC119 UNC119 AURKB AURKB CKAP2 CKAP2 KATNAL1 KATNAL1 LATS2 LATS2 KNTC1 KNTC1 NEDD1 NEDD1 POC1B POC1B AAAS AAAS PLEKHG6 PLEKHG6 ZW10 ZW10 KAT5 KAT5 CK820_G0051369 CK820_G0051369 BCCIP BCCIP KIF11 KIF11 CENPF CENPF NEK2 NEK2 NEK7 NEK7 GPSM2 GPSM2 PLK3 PLK3 CDC20 CDC20 CEP104 CEP104 KATNB1 KATNB1 WDR73 WDR73 TUBGCP4 TUBGCP4 RMDN3 RMDN3 KNSTRN KNSTRN KATNBL1 KATNBL1 TUBGCP5 TUBGCP5 CEP128 CEP128 DLGAP5 DLGAP5 TUBGCP3 TUBGCP3 ENSPTRP00000087593 ENSPTRP00000087593 PPP2CB PPP2CB ENSPTRP00000088520 ENSPTRP00000088520 ENSPTRP00000088633 ENSPTRP00000088633 ALMS1 ALMS1 UXT UXT ENSPTRP00000090344 ENSPTRP00000090344 ENSPTRP00000090392 ENSPTRP00000090392 ENSPTRP00000090420 ENSPTRP00000090420 VPS4A VPS4A RASSF10 RASSF10 CDC14A CDC14A NEK6 NEK6 CK820_G0051860 CK820_G0051860 IK IK ENSPTRP00000092155 ENSPTRP00000092155 ENSPTRP00000092300 ENSPTRP00000092300 ENSPTRP00000092365 ENSPTRP00000092365 ENSPTRP00000092743 ENSPTRP00000092743 NEDD9 NEDD9 NUMA1 NUMA1 PLK1 PLK1 HSF1 HSF1 ENSPTRP00000087352 ENSPTRP00000087352 ENSPTRP00000087196 ENSPTRP00000087196 CK820_G0019512 CK820_G0019512 CEP85 CEP85 BIRC6 BIRC6 STAG1 STAG1 ENSPTRP00000085517 ENSPTRP00000085517 ENSPTRP00000085241 ENSPTRP00000085241 HNRNPU HNRNPU ENSPTRP00000083882 ENSPTRP00000083882 CDC14C CDC14C ENSPTRP00000083584 ENSPTRP00000083584 ENSPTRP00000083219 ENSPTRP00000083219 ENSPTRP00000083030 ENSPTRP00000083030 CALM1 CALM1 NIN NIN LOC101058196 LOC101058196 IKBKG IKBKG FBF1 FBF1 ENSPTRP00000081784 ENSPTRP00000081784 GOLGA2-2 GOLGA2-2 CK820_G0019795 CK820_G0019795 RAB11A RAB11A ENSPTRP00000079401 ENSPTRP00000079401 LOC737111 LOC737111 SMC6 SMC6 CEP44 CEP44 ENSPTRP00000078364 ENSPTRP00000078364 MTCL1 MTCL1 EFHC1 EFHC1 UMOD UMOD LOC100610002 LOC100610002 ENSPTRP00000075745 ENSPTRP00000075745 ENSPTRP00000075388 ENSPTRP00000075388 TNKS TNKS LOC737257 LOC737257 ENSPTRP00000074371 ENSPTRP00000074371 ENSPTRP00000074041 ENSPTRP00000074041 NDE1 NDE1 AURKB-2 AURKB-2 FAM161A FAM161A ENSPTRP00000072741 ENSPTRP00000072741 KATNAL2 KATNAL2 BRCC3 BRCC3 DDX11 DDX11 ENSPTRP00000071713 ENSPTRP00000071713 LOC104001660 LOC104001660 EFCAB13 EFCAB13 ENSPTRP00000071420 ENSPTRP00000071420 LOC742392 LOC742392 MAPKBP1 MAPKBP1 TMEM201 TMEM201 NPM1 NPM1 ENSPTRP00000067444 ENSPTRP00000067444 TBCCD1 TBCCD1 LOC743115 LOC743115 ENSPTRP00000066329 ENSPTRP00000066329 RMDN2 RMDN2 FRY FRY ODF2 ODF2 CALM2 CALM2 PKP4 PKP4 ENSPTRP00000065631 ENSPTRP00000065631 VPS4B VPS4B NUBP2 NUBP2 ENSPTRP00000063671 ENSPTRP00000063671 PPP2CA PPP2CA FAM110C FAM110C PSRC1 PSRC1 ARHGEF7 ARHGEF7 PLK5 PLK5 BEX4 BEX4 BOD1L2 BOD1L2 AUNIP AUNIP ENSPTRP00000059866 ENSPTRP00000059866 GIT1 GIT1 KIF2A KIF2A NPM1-2 NPM1-2 MAD1L1 MAD1L1 MAP10 MAP10 UBXN2B UBXN2B CDK5RAP2 CDK5RAP2 EML1 EML1 MAPRE1 MAPRE1 RAE1 RAE1 ASPM ASPM KLHL22 KLHL22 RALBP1 RALBP1 CETN1 CETN1 TOPORS TOPORS CNTRL CNTRL CKAP5 CKAP5 DCTN4 DCTN4 CDC14B CDC14B ABRAXAS2 ABRAXAS2 DNAAF1 DNAAF1 KIF20B KIF20B CTNNB1 CTNNB1 CK820_G0049038 CK820_G0049038 LRMP LRMP KLHL21 KLHL21 PRC1 PRC1 RMDN1 RMDN1 ENSPTRP00000043382 ENSPTRP00000043382 SPOUT1 SPOUT1 RASSF1 RASSF1 SMC3 SMC3 CDC25B CDC25B ANKRD53 ANKRD53 CSPP1 CSPP1 GOLGA2 GOLGA2 STAG2 STAG2 SMC1A SMC1A RAD21 RAD21 DYNC1I1 DYNC1I1 SBDS SBDS LATS1 LATS1 KATNA1 KATNA1 MAPK14 MAPK14 RGS14 RGS14 BOD1 BOD1 SPDL1 SPDL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUDCD2NudC domain-containing protein 2. (157 aa)
ENSPTRP00000029492annotation not available (223 aa)
CCNB1CCNB1 isoform 1; Belongs to the cyclin family. (433 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
PLK4Polo-like kinase 4. (970 aa)
MAD2L1MAD2 mitotic arrest deficient-like 1. (205 aa)
ALPK1ALPK1 isoform 3. (1244 aa)
BOD1L1BOD1L1 isoform 1. (3049 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (838 aa)
CEP19Chromosome 3 open reading frame 34. (167 aa)
CEP63Centrosomal protein 63kDa. (703 aa)
TOPBP1Topoisomerase (DNA) II binding protein 1. (1522 aa)
POC1APOC1 centriolar protein A. (369 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
SGO1Shugoshin-like 1. (527 aa)
AURKASerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
FAM83DFAM83D isoform 1. (613 aa)
TPX2TPX2, microtubule-associated, homolog. (728 aa)
FAM110AFamily with sequence similarity 110, member A. (295 aa)
CUL3CUL3 isoform 2; Belongs to the cullin family. (768 aa)
DCTN1T0125321 isoform 1. (1278 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
AURKCAURKC isoform 1; Belongs to the protein kinase superfamily. (309 aa)
CCDC155Coiled-coil domain containing 155. (562 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
WDR62WDR62 isoform 2. (1523 aa)
CEP89CEP89 isoform 2. (784 aa)
HAUS8HAUS8 isoform 1. (409 aa)
MISPMISP isoform 1. (679 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
HAUS1HAUS augmin like complex subunit 1. (278 aa)
CEP95Coiled-coil domain containing 45. (821 aa)
EFCAB3EF-hand calcium binding domain 3. (490 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
RSKRUncharacterized serine/threonine-protein kinase SgK494 isoform X1. (410 aa)
SPAG5Sperm associated antigen 5. (1199 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
AURKBAURKB isoform 1; Belongs to the protein kinase superfamily. (344 aa)
CKAP2Cytoskeleton associated protein 2. (682 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
LATS2Non-specific serine/threonine protein kinase. (1088 aa)
KNTC1Kinetochore associated 1. (2209 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (660 aa)
POC1BPOC1 centriolar protein homolog B isoform X2. (478 aa)
AAASAchalasia, adrenocortical insufficiency, alacrimia. (546 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
ZW10ZW10, kinetochore associated, homolog. (779 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
CK820_G0051369Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (911 aa)
BCCIPBRCA2 and CDKN1A interacting protein. (322 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CENPFCentromere protein F, 350/400kDa (Mitosin). (3114 aa)
NEK2NIMA (Never in mitosis gene a)-related kinase 2. (445 aa)
NEK7NIMA (Never in mitosis gene a)-related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
GPSM2G-protein-signaling modulator 2. (684 aa)
PLK3Serine/threonine-protein kinase PLK. (673 aa)
CDC20Cell division cycle 20 homolog. (499 aa)
CEP104Centrosomal protein 104. (925 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
WDR73WD repeat domain 73. (378 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
RMDN3Family with sequence similarity 82, member A2. (470 aa)
KNSTRNKNSTRN isoform 3. (316 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa)
CEP128Centrosomal protein 128. (1094 aa)
DLGAP5Discs, large homolog-associated protein 5. (846 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (907 aa)
ENSPTRP00000087593annotation not available (91 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ENSPTRP00000088520annotation not available (242 aa)
ENSPTRP00000088633annotation not available (430 aa)
ALMS1ALMS1 isoform 1. (4169 aa)
UXTUbiquitously expressed prefoldin like chaperone. (157 aa)
ENSPTRP00000090344annotation not available (218 aa)
ENSPTRP00000090392annotation not available (93 aa)
ENSPTRP00000090420annotation not available (273 aa)
VPS4AVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (505 aa)
RASSF10Ras association domain family member 10. (507 aa)
CDC14ACDC14A isoform 3. (606 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (373 aa)
CK820_G0051860DDX11 isoform 28. (265 aa)
IKIK isoform 2. (557 aa)
ENSPTRP00000092155annotation not available (179 aa)
ENSPTRP00000092300annotation not available (252 aa)
ENSPTRP00000092365annotation not available (128 aa)
ENSPTRP00000092743annotation not available (379 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2111 aa)
PLK1Serine/threonine-protein kinase PLK. (621 aa)
HSF1Heat shock transcription factor 1. (529 aa)
ENSPTRP00000087352annotation not available (158 aa)
ENSPTRP00000087196annotation not available (261 aa)
CK820_G0019512HAUS1 isoform 4. (91 aa)
CEP85Coiled-coil domain containing 21. (762 aa)
BIRC6BIRC6 isoform 5. (4904 aa)
STAG1Stromal antigen 1. (1258 aa)
ENSPTRP00000085517annotation not available (294 aa)
ENSPTRP00000085241annotation not available (93 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
ENSPTRP00000083882annotation not available (275 aa)
CDC14CDual specificity protein phosphatase CDC14C. (553 aa)
ENSPTRP00000083584annotation not available (275 aa)
ENSPTRP00000083219annotation not available (275 aa)
ENSPTRP00000083030annotation not available (225 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
NINNIN isoform 1. (2133 aa)
LOC101058196Golgin subfamily A member 6-like protein 9. (185 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
FBF1T0139750 isoform 2. (1181 aa)
ENSPTRP00000081784annotation not available (218 aa)
GOLGA2-2GOLGA2 isoform 4. (1034 aa)
CK820_G0019795KATNAL1 isoform 4. (405 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
ENSPTRP00000079401annotation not available (162 aa)
LOC737111Cell division cycle protein 20 homolog pseudogene. (482 aa)
SMC6Structural maintenance of chromosomes 6. (1160 aa)
CEP44Centrosomal protein 44. (399 aa)
ENSPTRP00000078364annotation not available (111 aa)
MTCL1MTCL1 isoform 8. (1905 aa)
EFHC1EF-hand domain containing 1. (641 aa)
UMODUMOD isoform 1. (690 aa)
LOC100610002IKBKG isoform 9. (401 aa)
ENSPTRP00000075745annotation not available (296 aa)
ENSPTRP00000075388annotation not available (529 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
LOC737257Nucleophosmin pseudogene. (312 aa)
ENSPTRP00000074371annotation not available (264 aa)
ENSPTRP00000074041annotation not available (223 aa)
NDE1NudE nuclear distribution gene E homolog 1. (359 aa)
AURKB-2Aurora kinase B. (344 aa)
FAM161AFAM161A isoform 2. (716 aa)
ENSPTRP00000072741annotation not available (133 aa)
KATNAL2KATNAL2 isoform 2. (538 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (317 aa)
DDX11DDX11 isoform 5. (933 aa)
ENSPTRP00000071713annotation not available (185 aa)
LOC104001660Putative golgin subfamily A member 2B. (141 aa)
EFCAB13EFCAB13 isoform 2. (167 aa)
ENSPTRP00000071420annotation not available (392 aa)
LOC742392Protein Red-like. (531 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1514 aa)
TMEM201Transmembrane protein 201. (666 aa)
NPM1NPM1 isoform 1. (294 aa)
ENSPTRP00000067444annotation not available (529 aa)
TBCCD1TBCC domain containing 1. (557 aa)
LOC743115Nucleophosmin pseudogene. (255 aa)
ENSPTRP00000066329annotation not available (241 aa)
RMDN2Regulator of microtubule dynamics 2. (618 aa)
FRYFRY isoform 4. (3016 aa)
ODF2Outer dense fiber of sperm tails 2. (829 aa)
CALM2CALM2 isoform 7; Belongs to the calmodulin family. (196 aa)
PKP4PKP4 isoform 4. (1202 aa)
ENSPTRP00000065631annotation not available (879 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (446 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (270 aa)
ENSPTRP00000063671annotation not available (122 aa)
PPP2CAPPP2CB isoform 8. (309 aa)
FAM110CFamily with sequence similarity 110 member C. (369 aa)
PSRC1PSRC1 isoform 1. (363 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
PLK5PLK5 isoform 3. (337 aa)
BEX4Brain expressed, X-linked 4. (120 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (171 aa)
AUNIPAurora kinase A and ninein interacting protein. (371 aa)
ENSPTRP00000059866annotation not available (108 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
NPM1-2NPM1 isoform 5. (306 aa)
MAD1L1MAD1 mitotic arrest deficient-like 1. (718 aa)
MAP10Microtubule associated protein 10. (1047 aa)
UBXN2BUBX domain protein 2B. (331 aa)
CDK5RAP2CDK5 regulatory subunit-associated protein 2; Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of [...] (1903 aa)
EML1EML1 isoform 2. (834 aa)
MAPRE1MAPRE1 isoform 1. (268 aa)
RAE1RAE1 RNA export 1 homolog. (368 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3477 aa)
KLHL22T0192575 isoform 1. (634 aa)
RALBP1RalA binding protein 1. (655 aa)
CETN1CETN1 isoform 1. (172 aa)
TOPORSTopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase. (1045 aa)
CNTRLCentrosomal protein 110kDa. (2325 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
DCTN4Dynactin subunit 4. (467 aa)
CDC14BCDC14 cell division cycle 14 homolog B. (498 aa)
ABRAXAS2Family with sequence similarity 175, member B. (415 aa)
DNAAF1Dynein assembly factor 1, axonemal. (725 aa)
KIF20BKIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
CK820_G0049038TUBGCP6 isoform 3. (1579 aa)
LRMPLymphoid restricted membrane protein. (1454 aa)
KLHL21Kelch like family member 21. (597 aa)
PRC1Protein regulator of cytokinesis 1. (620 aa)
RMDN1Family with sequence similarity 82, member B. (314 aa)
ENSPTRP00000043382annotation not available (185 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (376 aa)
RASSF1Ras association (RalGDS/AF-6) domain family member 1. (340 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
CDC25BCell division cycle 25 homolog B. (580 aa)
ANKRD53Ankyrin repeat domain 53. (530 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1221 aa)
GOLGA2GOLGA2 isoform 6. (1005 aa)
STAG2Stromal antigen 2. (1268 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
RAD21RAD21 cohesin complex component. (631 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
SBDSShwachman-Bodian-Diamond syndrome. (250 aa)
LATS1LATS, large tumor suppressor, homolog 1. (1130 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
BOD1Biorientation of chromosomes in cell division 1. (185 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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