STRINGSTRING
H2AZ1 H2AZ1 GTF2B GTF2B EZH2-2 EZH2-2 TAF1 TAF1 GTF2A1 GTF2A1 CEBPB CEBPB CK820_G0031483 CK820_G0031483 FOS FOS EZH2 EZH2 POU2F1 POU2F1 HDAC1 HDAC1 LOC748850 LOC748850 PAX6 PAX6 RUVBL2 RUVBL2 TBP TBP RELA RELA REST REST TBPL1 TBPL1 H2AFY H2AFY GBX2 GBX2 ENSPTRP00000090987 ENSPTRP00000090987 STAT1 STAT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2AZ1H2AFZ isoform 3. (128 aa)
GTF2BGeneral transcription factor IIB. (310 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
GTF2A1General transcription factor IIA, 1, 19/37kDa. (366 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
CK820_G0031483H2AFV isoform 8. (118 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
POU2F1POU domain protein. (766 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
LOC748850HDAC2 isoform 9. (445 aa)
PAX6PAX6 isoform 13. (436 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
TBPTBP isoform 1. (336 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
RESTRE1 silencing transcription factor. (1097 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
H2AFYH2AFY isoform 4. (372 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
ENSPTRP00000090987annotation not available (87 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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