STRINGSTRING
SYCP1 SYCP1 TAF3 TAF3 TESMIN TESMIN ZBTB16 ZBTB16 H2AFX H2AFX CTCF CTCF TERF2IP TERF2IP ZMYND15 ZMYND15 TOP2A TOP2A STPG4 STPG4 TSN TSN TNP1 TNP1 PCNA PCNA TOP1 TOP1 CK820_G0037203 CK820_G0037203 AIRE AIRE TOPBP1 TOPBP1 ACTRT3 ACTRT3 ANKRD37 ANKRD37 TRIP13 TRIP13 SPATA24 SPATA24 TBPL1 TBPL1 LOC107976163 LOC107976163 STAG3 STAG3 TRIM24 TRIM24 SPAG8 SPAG8 ACTL7A ACTL7A KDM3A KDM3A DAZAP1 DAZAP1 MAEL MAEL TERF2 TERF2 TBP TBP TAF4 TAF4 PATZ1 PATZ1 TAF10 TAF10 ENSPTRP00000062077 ENSPTRP00000062077 ADAD1 ADAD1 ENSPTRP00000066337 ENSPTRP00000066337 CDK2 CDK2 ENSPTRP00000067505 ENSPTRP00000067505 RAD51 RAD51 ENSPTRP00000069669 ENSPTRP00000069669 ENSPTRP00000073222 ENSPTRP00000073222 CDK7 CDK7 ZFPM2 ZFPM2 ENSPTRP00000076749 ENSPTRP00000076749 MLH3 MLH3 LIMK1-2 LIMK1-2 LOC100612812 LOC100612812 HSPA2 HSPA2 TRIM24-2 TRIM24-2 LOC107976163-2 LOC107976163-2 ENSPTRP00000083770 ENSPTRP00000083770 REC8 REC8 LIMK1 LIMK1 MLH1 MLH1 SMARCC1 SMARCC1 MORC1 MORC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYCP1Synaptonemal complex protein 1. (976 aa)
TAF3TATA-box binding protein associated factor 3. (931 aa)
TESMINTESMIN isoform 1. (508 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
H2AFXH2AFX isoform 1. (143 aa)
CTCFCCCTC-binding factor (Zinc finger protein). (727 aa)
TERF2IPTelomeric repeat binding factor 2, interacting protein. (399 aa)
ZMYND15Zinc finger MYND-type containing 15. (742 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
STPG4Protein STPG4 isoform X1. (246 aa)
TSNTSN isoform 1. (228 aa)
TNP1Spermatid nuclear transition protein 1. (55 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (765 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
AIREAutoimmune regulator. (545 aa)
TOPBP1Topoisomerase (DNA) II binding protein 1. (1522 aa)
ACTRT3Actin related protein M1; Belongs to the actin family. (372 aa)
ANKRD37Ankyrin repeat domain 37. (158 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
SPATA24Spermatogenesis associated 24. (293 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
LOC107976163Putative STAG3-like protein 1. (79 aa)
STAG3Stromal antigen 3. (1225 aa)
TRIM24Tripartite motif containing 24. (1054 aa)
SPAG8SPAG8 isoform 1. (497 aa)
ACTL7AActin-like protein 7A; Belongs to the actin family. (435 aa)
KDM3ALysine (K)-specific demethylase 3A. (1321 aa)
DAZAP1DAZAP1 isoform 7. (431 aa)
MAELMaelstrom spermatogenic transposon silencer. (434 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
TBPTBP isoform 1. (336 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
PATZ1POZ (BTB) and AT hook containing zinc finger 1. (687 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
ENSPTRP00000062077annotation not available (236 aa)
ADAD1Adenosine deaminase domain containing 1. (565 aa)
ENSPTRP00000066337annotation not available (155 aa)
CDK2CDK2 isoform 4; Belongs to the protein kinase superfamily. (346 aa)
ENSPTRP00000067505annotation not available (162 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
ENSPTRP00000069669annotation not available (324 aa)
ENSPTRP00000073222annotation not available (409 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ZFPM2ZFPM2 isoform 3. (1151 aa)
ENSPTRP00000076749annotation not available (243 aa)
MLH3MLH3 isoform 1. (1451 aa)
LIMK1-2LIM domain kinase 1. (677 aa)
LOC100612812LOW QUALITY PROTEIN: spermatid-specific linker histone H1-like protein. (231 aa)
HSPA2Heat shock 70kDa protein 2; Belongs to the heat shock protein 70 family. (642 aa)
TRIM24-2Tripartite motif containing 24. (1050 aa)
LOC107976163-2Putative STAG3-like protein 1. (79 aa)
ENSPTRP00000083770Transcription factor like 5. (432 aa)
REC8Meiotic recombination protein REC8-like 1. (547 aa)
LIMK1LIM domain kinase 1. (677 aa)
MLH1MutL homolog 1, colon cancer, nonpolyposis type 2. (756 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
MORC1MORC family CW-type zinc finger 1. (984 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.