51 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPTRP00000086173	annotation not available (566 aa)
	STAT3	Signal transducer and activator of transcription. (790 aa)
	RORB	RAR related orphan receptor B. (482 aa)
	TULP1	Tubby-like protein; Belongs to the TUB family. (542 aa)
	CABP4	Calcium binding protein 4. (275 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	ENSPTRP00000063978	annotation not available (224 aa)
	OLFM3	OLFM3 isoform 2. (478 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	TH	Tyrosine hydroxylase. (528 aa)
	CNTF	Ciliary neurotrophic factor. (200 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	MFRP	Membrane frizzled-related protein. (579 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	CEP290	CEP290 isoform 5. (2454 aa)
	NRL	Neural retina leucine zipper. (237 aa)
	SOX8	SOX8 isoform 1. (446 aa)
	RPGRIP1L	RPGRIP1L isoform 4. (1269 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (743 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	SDK2	SDK2 isoform 1. (2172 aa)
	RDH13	Retinol dehydrogenase 13 (All-trans/9-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	BHLHE23	Basic helix-loop-helix family member e23. (241 aa)
	DSCAM	DS cell adhesion molecule. (2012 aa)
	GNAT1	G protein subunit alpha transducin 1. (350 aa)
	PPP2R3A	PPP2R3A isoform 1. (1150 aa)
	PROM1	PROM1 isoform 12. (865 aa)
	HCN1	HCN1 isoform 1. (886 aa)
	PDE6C	Phosphodiesterase. (858 aa)
	PRDM1	PR/SET domain 1. (825 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	RP1	RP1 axonemal microtubule associated. (2156 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	TTC8	Tetratricopeptide repeat domain 8. (531 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
	AGTPBP1	ATP/GTP binding protein 1. (1290 aa)
	CRB2	CRB2 isoform 1. (1285 aa)
	CRB1	Crumbs cell polarity complex component 1. (1406 aa)
	USH1C	USH1C isoform 4. (899 aa)
	TOPORS	Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase. (1045 aa)
	CK820_G0047988	Fascin. (461 aa)
	NKD1	NKD inhibitor of WNT signaling pathway 1. (470 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	RPGRIP1	RPGR interacting protein 1. (1287 aa)
	DZANK1	DZANK1 isoform 3. (777 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (410 aa)
	MYO7A	MYO7A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2222 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	ROM1-2	Retinal outer segment membrane protein 1. (351 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS4	CEP290	ENSPTRP00000057396	ENSPTRP00000008971	Bardet-Biedl syndrome 4.	CEP290 isoform 5.	0.738
BBS4	RPGRIP1L	ENSPTRP00000057396	ENSPTRP00000013851	Bardet-Biedl syndrome 4.	RPGRIP1L isoform 4.	0.567
BBS4	TTC8	ENSPTRP00000057396	ENSPTRP00000066504	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.998
CABP4	GNAT1	ENSPTRP00000072433	ENSPTRP00000025800	Calcium binding protein 4.	G protein subunit alpha transducin 1.	0.528
CABP4	NR2E3	ENSPTRP00000072433	ENSPTRP00000075964	Calcium binding protein 4.	Nuclear receptor subfamily 2 group E member 3.	0.653
CABP4	ROM1	ENSPTRP00000072433	ENSPTRP00000006484	Calcium binding protein 4.	Retinal outer segment membrane protein 1.	0.606
CABP4	ROM1-2	ENSPTRP00000072433	ENSPTRP00000085720	Calcium binding protein 4.	Retinal outer segment membrane protein 1.	0.606
CABP4	RPGRIP1	ENSPTRP00000072433	ENSPTRP00000073611	Calcium binding protein 4.	RPGR interacting protein 1.	0.494
CABP4	TULP1	ENSPTRP00000072433	ENSPTRP00000092527	Calcium binding protein 4.	Tubby-like protein; Belongs to the TUB family.	0.483
CEP290	BBS4	ENSPTRP00000008971	ENSPTRP00000057396	CEP290 isoform 5.	Bardet-Biedl syndrome 4.	0.738
CEP290	RPGRIP1	ENSPTRP00000008971	ENSPTRP00000073611	CEP290 isoform 5.	RPGR interacting protein 1.	0.786
CEP290	RPGRIP1L	ENSPTRP00000008971	ENSPTRP00000013851	CEP290 isoform 5.	RPGRIP1L isoform 4.	0.819
CEP290	TTC8	ENSPTRP00000008971	ENSPTRP00000066504	CEP290 isoform 5.	Tetratricopeptide repeat domain 8.	0.525
CEP290	TULP1	ENSPTRP00000008971	ENSPTRP00000092527	CEP290 isoform 5.	Tubby-like protein; Belongs to the TUB family.	0.600
CK820_G0047988	MYO7A	ENSPTRP00000052666	ENSPTRP00000076334	Fascin.	MYO7A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.894
CK820_G0047988	NR2E3	ENSPTRP00000052666	ENSPTRP00000075964	Fascin.	Nuclear receptor subfamily 2 group E member 3.	0.567
CK820_G0047988	NRL	ENSPTRP00000052666	ENSPTRP00000010505	Fascin.	Neural retina leucine zipper.	0.644
CK820_G0047988	ROM1	ENSPTRP00000052666	ENSPTRP00000006484	Fascin.	Retinal outer segment membrane protein 1.	0.539
CK820_G0047988	ROM1-2	ENSPTRP00000052666	ENSPTRP00000085720	Fascin.	Retinal outer segment membrane protein 1.	0.539
CK820_G0047988	TOPORS	ENSPTRP00000052666	ENSPTRP00000049387	Fascin.	Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase.	0.588