STRINGSTRING
SEMA6C SEMA6C NRP1 NRP1 RET RET FGF19 FGF19 FOLR1 FOLR1 ALX1 ALX1 KITLG KITLG CORO1C CORO1C EDNRB EDNRB HIF1A HIF1A SEMA7A SEMA7A SEMA4B SEMA4B SOX8 SOX8 SEMA6B SEMA6B NRTN NRTN SEMA4C SEMA4C NRP2 NRP2 HTR2B HTR2B GBX2 GBX2 TBX1 TBX1 SEMA3G SEMA3G SEMA5B SEMA5B PHOX2B PHOX2B PITX2 PITX2 EDNRA EDNRA SEMA5A SEMA5A ISL1 ISL1 EDN1 EDN1 SEMA3C SEMA3C SEMA3A SEMA3A SEMA3D SEMA3D SMO SMO SOX10 SOX10 FN1 FN1 SEMA4F SEMA4F TWIST1 TWIST1 GDNF GDNF SEMA4D SEMA4D HAND2 HAND2 RADIL RADIL ERBB4 ERBB4 PHACTR4 PHACTR4 SEMA3E SEMA3E SEMA6A SEMA6A SMO-2 SMO-2 SEMA4A SEMA4A EDN3 EDN3 SHH SHH ACVR1 ACVR1 SEMA4G SEMA4G CDC42 CDC42 SEMA3F SEMA3F ANXA6 ANXA6 SEMA6D SEMA6D SEMA3B SEMA3B ENSPTRP00000087014 ENSPTRP00000087014 LAMA5 LAMA5 EFNB1 EFNB1 OVOL2 OVOL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA6CSEMA6C isoform 2; Belongs to the semaphorin family. (962 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FOLR1Folate receptor alpha. (257 aa)
ALX1ALX homeobox 1. (326 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SEMA7ASEMA7A isoform 1; Belongs to the semaphorin family. (664 aa)
SEMA4BSEMA4B isoform 1; Belongs to the semaphorin family. (836 aa)
SOX8SOX8 isoform 1. (446 aa)
SEMA6BSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)
NRTNNRTN isoform 1. (197 aa)
SEMA4CSEMA4C isoform 2; Belongs to the semaphorin family. (833 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
TBX1TBX1 isoform 1. (478 aa)
SEMA3GSEMA3G isoform 2; Belongs to the semaphorin family. (782 aa)
SEMA5BSEMA5B isoform 1. (1352 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
PITX2Homeobox protein. (324 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SEMA5ASEMA5A isoform 1. (1074 aa)
ISL1ISL LIM homeobox 1. (349 aa)
EDN1EDN1 isoform 1. (212 aa)
SEMA3CSEMA3C isoform 1; Belongs to the semaphorin family. (751 aa)
SEMA3ASEMA3A isoform 1; Belongs to the semaphorin family. (771 aa)
SEMA3DSEMA3D isoform 1; Belongs to the semaphorin family. (777 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
SOX10SRY-box transcription factor 10. (466 aa)
FN1FN1 isoform 1. (2477 aa)
SEMA4FSEMA4F isoform 1; Belongs to the semaphorin family. (770 aa)
TWIST1TWIST1 isoform 2. (163 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
RADILRap associating with DIL domain. (1075 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
SEMA3ESEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
SEMA6ASEMA6A isoform 2; Belongs to the semaphorin family. (1047 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
SEMA4ASEMA4A isoform 10; Belongs to the semaphorin family. (761 aa)
EDN3EDN3 isoform 1. (238 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
SEMA4GSEMA4G isoform 3; Belongs to the semaphorin family. (843 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
SEMA3FSEMA3F isoform 2; Belongs to the semaphorin family. (785 aa)
ANXA6Annexin. (788 aa)
SEMA6DSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6D; Belongs to the semaphorin family. (1086 aa)
SEMA3BSEMA3B isoform 2; Belongs to the semaphorin family. (749 aa)
ENSPTRP00000087014annotation not available (777 aa)
LAMA5Laminin, alpha 5. (2203 aa)
EFNB1EFNB1 isoform 1; Belongs to the ephrin family. (346 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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