STRINGSTRING
JAG1 JAG1 NOL3 NOL3 AGTR2 AGTR2 HOXA3-2 HOXA3-2 DLL4 DLL4 HOXA3 HOXA3 FOXC1 FOXC1 ATP7A ATP7A FLNA FLNA FOXC2 FOXC2 BAK1 BAK1 BMPR2 BMPR2 CRB1 CRB1 DBH DBH EXT1 EXT1 CHD7 CHD7 NOS3 NOS3 SEMA3C SEMA3C RSPO3 RSPO3 ATG5 ATG5 EDNRA EDNRA CCR2 CCR2 LIF LIF CBS CBS FGF8 FGF8 EPAS1 EPAS1 ACVRL1 ACVRL1 BAX BAX ENSPTRP00000092702 ENSPTRP00000092702 MEF2C MEF2C AXL AXL FGF10 FGF10 RBPJ RBPJ ENSPTRP00000078515 ENSPTRP00000078515 ACVR2B ACVR2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NOL3Nucleolar protein 3. (219 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
HOXA3-2Homeobox A3. (443 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
HOXA3HOXA3 isoform 3. (443 aa)
FOXC1FOXC1 isoform 1. (550 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
FLNAFLNA isoform 8. (2711 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
BAK1BCL2-antagonist/killer 1. (211 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
DBHDopamine beta-hydroxylase. (617 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
CHD7CHD7 isoform 1. (2997 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
SEMA3CSEMA3C isoform 1; Belongs to the semaphorin family. (751 aa)
RSPO3RSPO3 isoform 1. (292 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LIFLeukemia inhibitory factor (Cholinergic differentiation factor). (202 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (551 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
BAXBAX isoform 7. (123 aa)
ENSPTRP00000092702annotation not available (482 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
ENSPTRP00000078515annotation not available (198 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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