STRINGSTRING
BMP4 BMP4 GDF11 GDF11 PGR PGR SIDT2 SIDT2 CDH2 CDH2 PDPK1 PDPK1 HNF4A HNF4A RFX3 RFX3 WNT5A WNT5A RARG RARG RARB RARB BMP4-2 BMP4-2 SLC9A4 SLC9A4 BHLHA15-2 BHLHA15-2 GPAT4 GPAT4 SMO-2 SMO-2 PAX6 PAX6 ENSPTRP00000065272 ENSPTRP00000065272 GATA2 GATA2 RARA RARA SMO SMO BHLHA15 BHLHA15 CDK6 CDK6 DLL1 DLL1 BMP5 BMP5 SPDEF SPDEF BMP6 BMP6 NKX6-1 NKX6-1 NKX2-2 NKX2-2 FZD5 FZD5 FASN FASN HIF1A HIF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4. (408 aa)
GDF11GDF11 isoform 1. (407 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (933 aa)
SIDT2SID1 transmembrane family member 2 isoform X7. (854 aa)
CDH2Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
RFX3RFX3 isoform 4. (761 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RARGRetinoic acid receptor, gamma. (456 aa)
RARBRetinoic acid receptor, beta. (448 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
GPAT41-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta). (456 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
PAX6PAX6 isoform 13. (436 aa)
ENSPTRP00000065272annotation not available (328 aa)
GATA2GATA binding protein 2. (480 aa)
RARARARA isoform 4. (624 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
BMP6Bone morphogenetic protein 6. (512 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
FASNFatty acid synthase. (2511 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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