STRINGSTRING
HOXB13 HOXB13 TYMS TYMS TGFB1 TGFB1 SIX3 SIX3 EPAS1 EPAS1 TFCP2L1 TFCP2L1 FZD5 FZD5 KDR KDR NKX6-1 NKX6-1 RFX3 RFX3 LOC743215 LOC743215 FEM1B FEM1B ENSPTRP00000080279 ENSPTRP00000080279 BHLHA15-2 BHLHA15-2 ENSPTRP00000070319 ENSPTRP00000070319 GPAT4 GPAT4 ENSPTRP00000067500 ENSPTRP00000067500 ENSPTRP00000065272 ENSPTRP00000065272 ENSPTRP00000063255 ENSPTRP00000063255 FOXA1 FOXA1 GATA2 GATA2 AKR1B1 AKR1B1 BHLHA15 BHLHA15 HOXA5 HOXA5 TMEM79 TMEM79 PGR PGR GDF11 GDF11 HIF1A HIF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXB13HOXB13 isoform 1. (284 aa)
TYMSThymidylate synthetase. (313 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SIX3SIX homeobox 3. (331 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
TFCP2L1Transcription factor CP2 like 1. (479 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
RFX3RFX3 isoform 4. (761 aa)
LOC743215AKR1B1 isoform 13. (294 aa)
FEM1BFEM1B isoform 1. (627 aa)
ENSPTRP00000080279annotation not available (270 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
ENSPTRP00000070319annotation not available (244 aa)
GPAT41-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta). (456 aa)
ENSPTRP00000067500annotation not available (264 aa)
ENSPTRP00000065272annotation not available (328 aa)
ENSPTRP00000063255annotation not available (394 aa)
FOXA1FOXA1 isoform 1. (471 aa)
GATA2GATA binding protein 2. (480 aa)
AKR1B1Aldo-keto reductase family 1, member B1 (Aldose reductase). (316 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
HOXA5HOXA5 isoform 1. (270 aa)
TMEM79Transmembrane protein 79. (394 aa)
PGRProgesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (933 aa)
GDF11GDF11 isoform 1. (407 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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