28 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXB13	HOXB13 isoform 1. (284 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SIX3	SIX homeobox 3. (331 aa)
	EPAS1	Endothelial PAS domain protein 1. (870 aa)
	TFCP2L1	Transcription factor CP2 like 1. (479 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	NKX6-1	NKX6-1 isoform 2. (367 aa)
	RFX3	RFX3 isoform 4. (761 aa)
	LOC743215	AKR1B1 isoform 13. (294 aa)
	FEM1B	FEM1B isoform 1. (627 aa)
	ENSPTRP00000080279	annotation not available (270 aa)
	BHLHA15-2	Basic helix-loop-helix family member a15. (189 aa)
	ENSPTRP00000070319	annotation not available (244 aa)
	GPAT4	1-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta). (456 aa)
	ENSPTRP00000067500	annotation not available (264 aa)
	ENSPTRP00000065272	annotation not available (328 aa)
	ENSPTRP00000063255	annotation not available (394 aa)
	FOXA1	FOXA1 isoform 1. (471 aa)
	GATA2	GATA binding protein 2. (480 aa)
	AKR1B1	Aldo-keto reductase family 1, member B1 (Aldose reductase). (316 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (189 aa)
	HOXA5	HOXA5 isoform 1. (270 aa)
	TMEM79	Transmembrane protein 79. (394 aa)
	PGR	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation. (933 aa)
	GDF11	GDF11 isoform 1. (407 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000080279	GATA2	ENSPTRP00000080279	ENSPTRP00000054198	annotation not available	GATA binding protein 2.	0.508
EPAS1	FEM1B	ENSPTRP00000020413	ENSPTRP00000081740	Endothelial PAS domain protein 1.	FEM1B isoform 1.	0.452
EPAS1	HIF1A	ENSPTRP00000020413	ENSPTRP00000010887	Endothelial PAS domain protein 1.	Hypoxia inducible factor 1 subunit alpha.	0.997
EPAS1	KDR	ENSPTRP00000020413	ENSPTRP00000027639	Endothelial PAS domain protein 1.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.514
FEM1B	EPAS1	ENSPTRP00000081740	ENSPTRP00000020413	FEM1B isoform 1.	Endothelial PAS domain protein 1.	0.452
FEM1B	HIF1A	ENSPTRP00000081740	ENSPTRP00000010887	FEM1B isoform 1.	Hypoxia inducible factor 1 subunit alpha.	0.423
FOXA1	GATA2	ENSPTRP00000062658	ENSPTRP00000054198	FOXA1 isoform 1.	GATA binding protein 2.	0.715
FOXA1	HOXB13	ENSPTRP00000062658	ENSPTRP00000015908	FOXA1 isoform 1.	HOXB13 isoform 1.	0.557
FOXA1	PGR	ENSPTRP00000062658	ENSPTRP00000007237	FOXA1 isoform 1.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.775
FZD5	TFCP2L1	ENSPTRP00000021982	ENSPTRP00000021253	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Transcription factor CP2 like 1.	0.679
GATA2	ENSPTRP00000080279	ENSPTRP00000054198	ENSPTRP00000080279	GATA binding protein 2.	annotation not available	0.508
GATA2	FOXA1	ENSPTRP00000054198	ENSPTRP00000062658	GATA binding protein 2.	FOXA1 isoform 1.	0.715
GATA2	HIF1A	ENSPTRP00000054198	ENSPTRP00000010887	GATA binding protein 2.	Hypoxia inducible factor 1 subunit alpha.	0.482
GATA2	KDR	ENSPTRP00000054198	ENSPTRP00000027639	GATA binding protein 2.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.582
GATA2	PGR	ENSPTRP00000054198	ENSPTRP00000007237	GATA binding protein 2.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.621
HIF1A	EPAS1	ENSPTRP00000010887	ENSPTRP00000020413	Hypoxia inducible factor 1 subunit alpha.	Endothelial PAS domain protein 1.	0.997
HIF1A	FEM1B	ENSPTRP00000010887	ENSPTRP00000081740	Hypoxia inducible factor 1 subunit alpha.	FEM1B isoform 1.	0.423
HIF1A	GATA2	ENSPTRP00000010887	ENSPTRP00000054198	Hypoxia inducible factor 1 subunit alpha.	GATA binding protein 2.	0.482
HIF1A	KDR	ENSPTRP00000010887	ENSPTRP00000027639	Hypoxia inducible factor 1 subunit alpha.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.591
HIF1A	PGR	ENSPTRP00000010887	ENSPTRP00000007237	Hypoxia inducible factor 1 subunit alpha.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.580