5 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NODAL	NODAL isoform 2. (347 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	HES1	ENSPTRP00000032142	ENSPTRP00000064171	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 1.	0.499
DLL1	JAG1	ENSPTRP00000032142	ENSPTRP00000022729	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.712
DLL1	NOTCH1	ENSPTRP00000032142	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.998
HES1	DLL1	ENSPTRP00000064171	ENSPTRP00000032142	Hes family bHLH transcription factor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.499
HES1	JAG1	ENSPTRP00000064171	ENSPTRP00000022729	Hes family bHLH transcription factor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.532
HES1	NOTCH1	ENSPTRP00000064171	ENSPTRP00000036924	Hes family bHLH transcription factor 1.	NOTCH1 isoform 1.	0.642
JAG1	DLL1	ENSPTRP00000022729	ENSPTRP00000032142	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.712
JAG1	HES1	ENSPTRP00000022729	ENSPTRP00000064171	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes family bHLH transcription factor 1.	0.532
JAG1	NOTCH1	ENSPTRP00000022729	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.999
NOTCH1	DLL1	ENSPTRP00000036924	ENSPTRP00000032142	NOTCH1 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.998
NOTCH1	HES1	ENSPTRP00000036924	ENSPTRP00000064171	NOTCH1 isoform 1.	Hes family bHLH transcription factor 1.	0.642
NOTCH1	JAG1	ENSPTRP00000036924	ENSPTRP00000022729	NOTCH1 isoform 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.999