14 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (408 aa)
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (125 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
	LIG4	DNA ligase. (911 aa)
	PRKDC	Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family. (4128 aa)
	SOX4	Transcription factor SOX. (474 aa)
	TREX1	Three prime repair exonuclease 1. (369 aa)
	GATA3	GATA binding protein 3. (444 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	SPI1	Spi-1 proto-oncogene. (270 aa)
	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BATF	GATA3	ENSPTRP00000011135	ENSPTRP00000064658	Basic leucine zipper ATF-like transcription factor.	GATA binding protein 3.	0.540
BATF	SPI1	ENSPTRP00000011135	ENSPTRP00000084012	Basic leucine zipper ATF-like transcription factor.	Spi-1 proto-oncogene.	0.585
BCL2	FLT3	ENSPTRP00000090293	ENSPTRP00000009773	BCL2 apoptosis regulator.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.463
BCL2	KIT	ENSPTRP00000090293	ENSPTRP00000027637	BCL2 apoptosis regulator.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.554
BMP4	SHH	ENSPTRP00000010780	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
BMP4-2	SHH	ENSPTRP00000080656	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
FLT3	BCL2	ENSPTRP00000009773	ENSPTRP00000090293	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	BCL2 apoptosis regulator.	0.463
FLT3	SPI1	ENSPTRP00000009773	ENSPTRP00000084012	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Spi-1 proto-oncogene.	0.949
GATA3	BATF	ENSPTRP00000064658	ENSPTRP00000011135	GATA binding protein 3.	Basic leucine zipper ATF-like transcription factor.	0.540
GATA3	KIT	ENSPTRP00000064658	ENSPTRP00000027637	GATA binding protein 3.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.461
GATA3	SOX4	ENSPTRP00000064658	ENSPTRP00000050537	GATA binding protein 3.	Transcription factor SOX.	0.538
GATA3	SPI1	ENSPTRP00000064658	ENSPTRP00000084012	GATA binding protein 3.	Spi-1 proto-oncogene.	0.790
KIT	BCL2	ENSPTRP00000027637	ENSPTRP00000090293	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	BCL2 apoptosis regulator.	0.554
KIT	GATA3	ENSPTRP00000027637	ENSPTRP00000064658	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	GATA binding protein 3.	0.461
KIT	SPI1	ENSPTRP00000027637	ENSPTRP00000084012	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Spi-1 proto-oncogene.	0.635
LIG4	PRKDC	ENSPTRP00000042757	ENSPTRP00000045268	DNA ligase.	Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family.	0.988
LIG4	XRCC4	ENSPTRP00000042757	ENSPTRP00000084647	DNA ligase.	X-ray repair complementing defective repair in Chinese hamster cells 4.	0.882
PRKDC	LIG4	ENSPTRP00000045268	ENSPTRP00000042757	Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family.	DNA ligase.	0.988
PRKDC	XRCC4	ENSPTRP00000045268	ENSPTRP00000084647	Protein kinase, DNA-activated, catalytic polypeptide; Belongs to the PI3/PI4-kinase family.	X-ray repair complementing defective repair in Chinese hamster cells 4.	0.721
SHH	BMP4	ENSPTRP00000075730	ENSPTRP00000010780	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.720