STRINGSTRING
ACVR1 ACVR1 RBPJ RBPJ STK3 STK3 NRG1 NRG1 OVOL2 OVOL2 SMAD4 SMAD4 SOX18 SOX18 KDR KDR SOX17 SOX17 NOTCH1 NOTCH1 PROX1 PROX1 STK4 STK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
STK3Serine/threonine kinase 3. (519 aa)
NRG1NRG1 isoform 3. (713 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SOX18SOX18 isoform 1. (384 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SOX17SOX17 isoform 1. (416 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
PROX1Prospero homeobox 1. (737 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.