STRINGSTRING
NRG1 NRG1 SHOX2 SHOX2 GJA5 GJA5 TBX3 TBX3 ENSPTRP00000084126 ENSPTRP00000084126 BMP4-2 BMP4-2 SMAD5 SMAD5 CDC42 CDC42 GATA4 GATA4 NOTCH2 NOTCH2 SCN5A SCN5A HEY1 HEY1 TBX5 TBX5 LOC736481 LOC736481 HOPX HOPX CACNA1G CACNA1G ENSPTRP00000064416 ENSPTRP00000064416 MAML1 MAML1 GJB6 GJB6 MSC MSC NOTCH1 NOTCH1 HEY2 HEY2 BVES BVES TBX18 TBX18 NKX2-5 NKX2-5 ISL1 ISL1 SMAD1 SMAD1 ID2 ID2 SMAD4 SMAD4 DSG2 DSG2 GATA6 GATA6 IRX3 IRX3 MESP1 MESP1 HCN4 HCN4 BMP4 BMP4 BMPR1A BMPR1A NPPB NPPB NPPA NPPA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRG1NRG1 isoform 3. (713 aa)
SHOX2SHOX2 isoform 2. (343 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
TBX3T-box transcription factor 3. (743 aa)
ENSPTRP00000084126annotation not available (117 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
GATA4GATA binding protein 4. (443 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
TBX5T-box transcription factor 5. (518 aa)
LOC736481Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa)
HOPXHOPX isoform 3. (112 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
ENSPTRP00000064416annotation not available (502 aa)
MAML1MAML1 isoform 1. (1016 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (228 aa)
MSCMSC isoform 1. (295 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
BVESBlood vessel epicardial substance. (360 aa)
TBX18T-box transcription factor 18. (607 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
DSG2DSG2 isoform 1. (1118 aa)
GATA6GATA binding protein 6. (594 aa)
IRX3Iroquois homeobox 3. (500 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NPPBNatriuretic peptide B. (134 aa)
NPPANatriuretic peptide A. (153 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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