13 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBX18	T-box transcription factor 18. (607 aa)
	CACNA1G	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	GATA6	GATA binding protein 6. (594 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	SHOX2	SHOX2 isoform 2. (343 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	GJB6	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (228 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	GATA6	ENSPTRP00000010780	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4	ISL1	ENSPTRP00000010780	ENSPTRP00000028882	Bone morphogenetic protein 4.	ISL LIM homeobox 1.	0.409
BMP4	TBX3	ENSPTRP00000010780	ENSPTRP00000084833	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.403
BMP4-2	GATA6	ENSPTRP00000080656	ENSPTRP00000016858	Bone morphogenetic protein 4.	GATA binding protein 6.	0.546
BMP4-2	ISL1	ENSPTRP00000080656	ENSPTRP00000028882	Bone morphogenetic protein 4.	ISL LIM homeobox 1.	0.409
BMP4-2	TBX3	ENSPTRP00000080656	ENSPTRP00000084833	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.403
CACNA1G	HCN4	ENSPTRP00000065836	ENSPTRP00000012412	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	0.508
GATA6	BMP4	ENSPTRP00000016858	ENSPTRP00000010780	GATA binding protein 6.	Bone morphogenetic protein 4.	0.546
GATA6	BMP4-2	ENSPTRP00000016858	ENSPTRP00000080656	GATA binding protein 6.	Bone morphogenetic protein 4.	0.546
GATA6	ISL1	ENSPTRP00000016858	ENSPTRP00000028882	GATA binding protein 6.	ISL LIM homeobox 1.	0.487
GATA6	TBX3	ENSPTRP00000016858	ENSPTRP00000084833	GATA binding protein 6.	T-box transcription factor 3.	0.514
GATA6	TBX5	ENSPTRP00000016858	ENSPTRP00000069028	GATA binding protein 6.	T-box transcription factor 5.	0.590
HCN4	CACNA1G	ENSPTRP00000012412	ENSPTRP00000065836	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.508
HCN4	ISL1	ENSPTRP00000012412	ENSPTRP00000028882	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	ISL LIM homeobox 1.	0.467
HCN4	SHOX2	ENSPTRP00000012412	ENSPTRP00000091815	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	SHOX2 isoform 2.	0.558
HCN4	TBX18	ENSPTRP00000012412	ENSPTRP00000031422	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	T-box transcription factor 18.	0.557
HCN4	TBX3	ENSPTRP00000012412	ENSPTRP00000084833	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	T-box transcription factor 3.	0.554
HCN4	TBX5	ENSPTRP00000012412	ENSPTRP00000069028	Hyperpolarization activated cyclic nucleotide gated potassium channel 4.	T-box transcription factor 5.	0.582
ISL1	BMP4	ENSPTRP00000028882	ENSPTRP00000010780	ISL LIM homeobox 1.	Bone morphogenetic protein 4.	0.409
ISL1	BMP4-2	ENSPTRP00000028882	ENSPTRP00000080656	ISL LIM homeobox 1.	Bone morphogenetic protein 4.	0.409