7 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRX3	Iroquois homeobox 3. (500 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	ENSPTRP00000084126	annotation not available (117 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	HOPX	HOPX isoform 3. (112 aa)
	NKX2-5	NKX2-5 isoform 1. (325 aa)
	ID2	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000084126	NKX2-5	ENSPTRP00000084126	ENSPTRP00000029961	annotation not available	NKX2-5 isoform 1.	0.585
ENSPTRP00000084126	TBX5	ENSPTRP00000084126	ENSPTRP00000069028	annotation not available	T-box transcription factor 5.	0.412
HOPX	NKX2-5	ENSPTRP00000065973	ENSPTRP00000029961	HOPX isoform 3.	NKX2-5 isoform 1.	0.599
ID2	NKX2-5	ENSPTRP00000019998	ENSPTRP00000029961	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein.	NKX2-5 isoform 1.	0.653
ID2	TBX5	ENSPTRP00000019998	ENSPTRP00000069028	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein.	T-box transcription factor 5.	0.412
NKX2-5	ENSPTRP00000084126	ENSPTRP00000029961	ENSPTRP00000084126	NKX2-5 isoform 1.	annotation not available	0.585
NKX2-5	HOPX	ENSPTRP00000029961	ENSPTRP00000065973	NKX2-5 isoform 1.	HOPX isoform 3.	0.599
NKX2-5	ID2	ENSPTRP00000029961	ENSPTRP00000019998	NKX2-5 isoform 1.	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein.	0.653
NKX2-5	TBX3	ENSPTRP00000029961	ENSPTRP00000084833	NKX2-5 isoform 1.	T-box transcription factor 3.	0.745
NKX2-5	TBX5	ENSPTRP00000029961	ENSPTRP00000069028	NKX2-5 isoform 1.	T-box transcription factor 5.	0.996
TBX3	NKX2-5	ENSPTRP00000084833	ENSPTRP00000029961	T-box transcription factor 3.	NKX2-5 isoform 1.	0.745
TBX3	TBX5	ENSPTRP00000084833	ENSPTRP00000069028	T-box transcription factor 3.	T-box transcription factor 5.	0.674
TBX5	ENSPTRP00000084126	ENSPTRP00000069028	ENSPTRP00000084126	T-box transcription factor 5.	annotation not available	0.412
TBX5	ID2	ENSPTRP00000069028	ENSPTRP00000019998	T-box transcription factor 5.	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein.	0.412
TBX5	NKX2-5	ENSPTRP00000069028	ENSPTRP00000029961	T-box transcription factor 5.	NKX2-5 isoform 1.	0.996
TBX5	TBX3	ENSPTRP00000069028	ENSPTRP00000084833	T-box transcription factor 5.	T-box transcription factor 3.	0.674