STRINGSTRING
NFATC1 NFATC1 TNFRSF1B TNFRSF1B TGFB2 TGFB2 BMP4 BMP4 SMAD6 SMAD6 JAG1 JAG1 HEY2 HEY2 TBX20 TBX20 NOS3 NOS3 BMPR2 BMPR2 TNFRSF1A TNFRSF1A HEY1 HEY1 ROBO1 ROBO1 NOTCH2 NOTCH2 STRA6 STRA6 RBPJ RBPJ SLIT2 SLIT2 BMP4-2 BMP4-2 GJA5 GJA5 HEYL HEYL ROBO2 ROBO2 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFATC1Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1. (853 aa)
TNFRSF1BTumor necrosis factor receptor superfamily, member 1B. (461 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
TBX20T-box transcription factor 20. (447 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
TNFRSF1ATumor necrosis factor receptor superfamily, member 1A. (455 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
ROBO1Roundabout guidance receptor 1. (1684 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.