32 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	ROBO2	Roundabout guidance receptor 2. (1439 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (328 aa)
	ELN	ELN isoform 3. (790 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	GATA4	GATA binding protein 4. (443 aa)
	GATA5	GATA binding protein 5. (397 aa)
	ROBO1	Roundabout guidance receptor 1. (1684 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	NFATC1	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1. (853 aa)
	GATA3	GATA binding protein 3. (444 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	TWIST1	TWIST1 isoform 2. (163 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
	TBX20	T-box transcription factor 20. (447 aa)
	HEY2	Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
	NKX2-5	NKX2-5 isoform 1. (325 aa)
	SLIT3	SLIT3 isoform 2. (1459 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	EMILIN1	Elastin microfibril interfacer 1. (1016 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	SMAD6	Mothers against decapentaplegic homolog. (496 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	RB1	RB transcriptional corepressor 1. (928 aa)
	EFNA1	EFNA1 isoform 2; Belongs to the ephrin family. (205 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
	NPPA	Natriuretic peptide A. (153 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	GATA4	ENSPTRP00000010780	ENSPTRP00000075865	Bone morphogenetic protein 4.	GATA binding protein 4.	0.781
BMP4	NKX2-5	ENSPTRP00000010780	ENSPTRP00000029961	Bone morphogenetic protein 4.	NKX2-5 isoform 1.	0.507
BMP4	SMAD6	ENSPTRP00000010780	ENSPTRP00000012318	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.636
BMP4	SOX9	ENSPTRP00000010780	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
BMP4-2	GATA4	ENSPTRP00000080656	ENSPTRP00000075865	Bone morphogenetic protein 4.	GATA binding protein 4.	0.781
BMP4-2	NKX2-5	ENSPTRP00000080656	ENSPTRP00000029961	Bone morphogenetic protein 4.	NKX2-5 isoform 1.	0.507
BMP4-2	SMAD6	ENSPTRP00000080656	ENSPTRP00000012318	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.636
BMP4-2	SOX9	ENSPTRP00000080656	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
DLL4	HEY1	ENSPTRP00000070341	ENSPTRP00000069126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes related family bHLH transcription factor with YRPW motif 1.	0.723
DLL4	HEY2	ENSPTRP00000070341	ENSPTRP00000031710	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif 2.	0.663
DLL4	HEYL	ENSPTRP00000070341	ENSPTRP00000089331	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hes related family bHLH transcription factor with YRPW motif like.	0.591
DLL4	JAG1	ENSPTRP00000070341	ENSPTRP00000022729	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.579
DLL4	NOTCH1	ENSPTRP00000070341	ENSPTRP00000036924	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NOTCH1 isoform 1.	0.991
DLL4	TGFB1	ENSPTRP00000070341	ENSPTRP00000018930	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.476
EFNA1	SLIT3	ENSPTRP00000002368	ENSPTRP00000029913	EFNA1 isoform 2; Belongs to the ephrin family.	SLIT3 isoform 2.	0.457
ELN	EMILIN1	ENSPTRP00000080940	ENSPTRP00000020186	ELN isoform 3.	Elastin microfibril interfacer 1.	0.672
ELN	TGFB1	ENSPTRP00000080940	ENSPTRP00000018930	ELN isoform 3.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.662
EMILIN1	ELN	ENSPTRP00000020186	ENSPTRP00000080940	Elastin microfibril interfacer 1.	ELN isoform 3.	0.672
GATA3	GATA4	ENSPTRP00000064658	ENSPTRP00000075865	GATA binding protein 3.	GATA binding protein 4.	0.435
GATA3	NFATC1	ENSPTRP00000064658	ENSPTRP00000065668	GATA binding protein 3.	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1.	0.521