STRINGSTRING
TBX5 TBX5 MKS1 MKS1 ISL1 ISL1 EYA1 EYA1 NOTCH1 NOTCH1 CTNNB1 CTNNB1 HAND2 HAND2 HES1 HES1 CK820_G0040666 CK820_G0040666
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX5T-box transcription factor 5. (518 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
ISL1ISL LIM homeobox 1. (349 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
CK820_G0040666Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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