19 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GDF11	GDF11 isoform 1. (407 aa)
	SIDT2	SID1 transmembrane family member 2 isoform X7. (854 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NKX2-2	NKX2-2 isoform 1. (273 aa)
	NKX6-1	NKX6-1 isoform 2. (367 aa)
	BMP6	Bone morphogenetic protein 6. (512 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	CDK6	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (189 aa)
	SMO	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	SMO-2	Smoothened, frizzled class receptor. (786 aa)
	BHLHA15-2	Basic helix-loop-helix family member a15. (189 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	RFX3	RFX3 isoform 4. (761 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	PDPK1	3-phosphoinositide dependent protein kinase-1. (542 aa)
	CDH2	Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP5	ENSPTRP00000010780	ENSPTRP00000031264	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.662
BMP4	BMP6	ENSPTRP00000010780	ENSPTRP00000030227	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.966
BMP4	WNT5A	ENSPTRP00000010780	ENSPTRP00000086163	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.520
BMP4-2	BMP5	ENSPTRP00000080656	ENSPTRP00000031264	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.662
BMP4-2	BMP6	ENSPTRP00000080656	ENSPTRP00000030227	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.678
BMP4-2	WNT5A	ENSPTRP00000080656	ENSPTRP00000086163	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.520
BMP5	BMP4	ENSPTRP00000031264	ENSPTRP00000010780	Bone morphogenetic protein 5.	Bone morphogenetic protein 4.	0.662
BMP5	BMP4-2	ENSPTRP00000031264	ENSPTRP00000080656	Bone morphogenetic protein 5.	Bone morphogenetic protein 4.	0.662
BMP6	BMP4	ENSPTRP00000030227	ENSPTRP00000010780	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.966
BMP6	BMP4-2	ENSPTRP00000030227	ENSPTRP00000080656	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.678
CDH2	HNF4A	ENSPTRP00000092804	ENSPTRP00000087554	Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins.	Hepatocyte nuclear factor 4 alpha.	0.463
CDH2	WNT5A	ENSPTRP00000092804	ENSPTRP00000086163	Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.401
HNF4A	CDH2	ENSPTRP00000087554	ENSPTRP00000092804	Hepatocyte nuclear factor 4 alpha.	Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.463
HNF4A	WNT5A	ENSPTRP00000087554	ENSPTRP00000086163	Hepatocyte nuclear factor 4 alpha.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.512
SMO	WNT5A	ENSPTRP00000033707	ENSPTRP00000086163	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.431
SMO-2	WNT5A	ENSPTRP00000067533	ENSPTRP00000086163	Smoothened, frizzled class receptor.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.431
WNT5A	BMP4	ENSPTRP00000086163	ENSPTRP00000010780	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 4.	0.520
WNT5A	BMP4-2	ENSPTRP00000086163	ENSPTRP00000080656	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 4.	0.520
WNT5A	CDH2	ENSPTRP00000086163	ENSPTRP00000092804	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.401
WNT5A	HNF4A	ENSPTRP00000086163	ENSPTRP00000087554	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Hepatocyte nuclear factor 4 alpha.	0.512