STRINGSTRING
CRB1 CRB1 VSX1 VSX1 PTF1A PTF1A THRB THRB SLC17A8 SLC17A8 TFAP2B TFAP2B NTRK2 NTRK2 SMARCD3-2 SMARCD3-2 GPM6A GPM6A RPGRIP1 RPGRIP1 SMARCA4 SMARCA4 ACTL6A ACTL6A CABP4 CABP4 CASP2-2 CASP2-2 ATP2B4 ATP2B4 FAT3 FAT3 TTC8 TTC8 HES1 HES1 ENSPTRP00000063978 ENSPTRP00000063978 NEUROD4 NEUROD4 FJX1 FJX1 RORB RORB MEGF11 MEGF11 OBSL1 OBSL1 BBS4 BBS4 LHX1 LHX1 ZHX2 ZHX2 USP45 USP45 SLC1A1 SLC1A1 TOPORS TOPORS USH1C USH1C ATP8A2 ATP8A2 ATP2B1 ATP2B1 CRB2 CRB2 RS1 RS1 NOTCH1 NOTCH1 CALB1 CALB1 RP1 RP1 SMARCD3 SMARCD3 CASP2 CASP2 HIPK2 HIPK2 TSPAN12 TSPAN12 SDK1 SDK1 AHI1 AHI1 PDE6C PDE6C HCN1 HCN1 PROM1 PROM1 DSCAM DSCAM BHLHE23 BHLHE23 TGIF2 TGIF2 IHH IHH RDH13 RDH13 SLC17A7 SLC17A7 BSG BSG PTPRM PTPRM SDK2 SDK2 SOX9 SOX9 NAGLU NAGLU RPGRIP1L RPGRIP1L SOX8 SOX8 PSEN1 PSEN1 NRL NRL FOXN4 FOXN4 GDF11 GDF11 THY1 THY1 ROM1 ROM1 CNTF CNTF IGSF22 IGSF22 ATOH7 ATOH7 TGFB2 TGFB2 HIPK1 HIPK1 GNAT2 GNAT2 BARHL2 BARHL2 RPE65 RPE65 STAT3 STAT3 IGFN1 IGFN1 TFAP2A TFAP2A ATP2B2 ATP2B2 ROM1-2 ROM1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRB1Crumbs cell polarity complex component 1. (1406 aa)
VSX1Visual system homeobox 1. (365 aa)
PTF1APancreas associated transcription factor 1a. (328 aa)
THRBThyroid hormone receptor beta. (476 aa)
SLC17A8SLC17A8 isoform 1. (589 aa)
TFAP2BTranscription factor AP-2 beta. (467 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
SMARCD3-2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
GPM6AGlycoprotein M6A. (278 aa)
RPGRIP1RPGR interacting protein 1. (1287 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ACTL6AACTL6A isoform 2; Belongs to the actin family. (430 aa)
CABP4Calcium binding protein 4. (275 aa)
CASP2-2Caspase 2. (452 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
FAT3FAT3 isoform 2. (4612 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSPTRP00000063978annotation not available (224 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
FJX1Four-jointed box kinase 1. (437 aa)
RORBRAR related orphan receptor B. (482 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
OBSL1OBSL1 isoform 6. (1895 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (814 aa)
SLC1A1Amino acid transporter. (524 aa)
TOPORSTopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase. (1045 aa)
USH1CUSH1C isoform 4. (899 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
CRB2CRB2 isoform 1. (1285 aa)
RS1Retinoschisin 1. (224 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
CALB1CALB1 isoform 3. (261 aa)
RP1RP1 axonemal microtubule associated. (2156 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
CASP2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (452 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
TSPAN12Tetraspanin. (305 aa)
SDK1SDK1 isoform 1. (2007 aa)
AHI1Abelson helper integration site 1. (1196 aa)
PDE6CPhosphodiesterase. (858 aa)
HCN1HCN1 isoform 1. (886 aa)
PROM1PROM1 isoform 12. (865 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
BHLHE23Basic helix-loop-helix family member e23. (241 aa)
TGIF2Homeobox protein TGIF2. (237 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
RDH13Retinol dehydrogenase 13 (All-trans/9-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
SLC17A7SLC17A7 isoform 1. (570 aa)
BSGBSG isoform 8. (383 aa)
PTPRMPTPRM isoform 4. (1465 aa)
SDK2SDK2 isoform 1. (2172 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
RPGRIP1LRPGRIP1L isoform 4. (1269 aa)
SOX8SOX8 isoform 1. (446 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
NRLNeural retina leucine zipper. (237 aa)
FOXN4FOXN4 isoform 2. (517 aa)
GDF11GDF11 isoform 1. (407 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IGSF22IGSF22 isoform 3. (1326 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HIPK1HIPK1 isoform 10. (1210 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
BARHL2BarH like homeobox 2. (387 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
IGFN1IGFN1 isoform 3. (3703 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ROM1-2Retinal outer segment membrane protein 1. (351 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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