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CATSPERE CATSPERE RYR1 RYR1 ENSPTRP00000093907 ENSPTRP00000093907 TMEM249-2 TMEM249-2 CK820_G0030361 CK820_G0030361 TMEM262 TMEM262 CACNA2D2 CACNA2D2 CACNB3 CACNB3 CACNB1 CACNB1 CACNA1A CACNA1A HSPA2 HSPA2 LOC107966461-2 LOC107966461-2 ENSPTRP00000078278 ENSPTRP00000078278 CACNG4 CACNG4 CACNA1D CACNA1D CACNA1S CACNA1S CACNA2D4 CACNA2D4 CACNA2D1 CACNA2D1 PDE4D PDE4D PDE4B PDE4B CACNA1G CACNA1G CATSPERD CATSPERD TMEM249 TMEM249 CACNA1I CACNA1I CACNB4 CACNB4 CACNA2D3 CACNA2D3 CACNG8 CACNG8 CACNB2 CACNB2 EFCAB9 EFCAB9 CACNA1F CACNA1F CACNA1B CACNA1B CATSPER3 CATSPER3 CACNG2 CACNG2 CACNG6 CACNG6 CACNG7 CACNG7 CATSPERG CATSPERG CACNG1 CACNG1 CACNA1H CACNA1H LOC107966461 LOC107966461 CATSPERB CATSPERB STAC3 STAC3 CACNA1C CACNA1C CATSPER1 CATSPER1 CACNA1E CACNA1E CACHD1 CACHD1 CATSPER4 CATSPER4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CATSPERECatsper channel auxiliary subunit epsilon. (959 aa)
RYR1RYR1 isoform 3. (5037 aa)
ENSPTRP00000093907annotation not available (528 aa)
TMEM249-2Transmembrane protein 249. (235 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
TMEM262Transmembrane protein 262. (116 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2504 aa)
HSPA2Heat shock 70kDa protein 2; Belongs to the heat shock protein 70 family. (642 aa)
LOC107966461-2Cation channel sperm-associated protein 2. (563 aa)
ENSPTRP00000078278annotation not available (260 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CACNA2D4CACNA2D4 isoform 6. (1154 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
PDE4DPhosphodiesterase. (809 aa)
PDE4BPhosphodiesterase. (736 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
CATSPERDCATSPERD isoform 1. (798 aa)
TMEM249Transmembrane protein 249. (235 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2223 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CACNA2D3CACNA2D3 isoform 3. (1091 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (427 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
EFCAB9EF-hand calcium binding domain 9. (197 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2312 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CATSPERGCation channel sperm associated auxiliary subunit gamma. (1159 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
CACNA1HCACNA1H isoform 1. (2240 aa)
LOC107966461CATSPER2 isoform 1. (563 aa)
CATSPERBCATSPERB isoform 2. (1086 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
CATSPER1Cation channel sperm associated 1. (780 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
CACHD1CACHD1 isoform 4. (1274 aa)
CATSPER4Cation channel sperm associated 4. (464 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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