STRINGSTRING
LOC742399 LOC742399 PHGDH PHGDH GLYAT GLYAT GCSH GCSH AGXT AGXT HAO1 HAO1 AMT AMT AGXT2 AGXT2 DHFR DHFR RIDA RIDA GART GART GLDC GLDC SHMT2 SHMT2 SHMT1 SHMT1 ENSPTRP00000077512 ENSPTRP00000077512 ENSPTRP00000081875 ENSPTRP00000081875 LOC736372 LOC736372 GART-2 GART-2 BAAT BAAT DHFR2 DHFR2 ENSPTRP00000092611 ENSPTRP00000092611
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC742399Glycine cleavage system H protein, mitochondrial. (172 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (573 aa)
GLYATGlycine-N-acyltransferase. (296 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
AGXTSerine--pyruvate aminotransferase. (367 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
AMTAminomethyltransferase, mitochondrial isoform X2. (403 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
DHFRDihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
SHMT1Serine hydroxymethyltransferase 1. (483 aa)
ENSPTRP00000077512annotation not available (168 aa)
ENSPTRP00000081875annotation not available (143 aa)
LOC736372Glycine dehydrogenase (decarboxylating), mitochondrial pseudogene. (980 aa)
GART-2annotation not available (1010 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (418 aa)
DHFR2DHFR2 isoform 2. (186 aa)
ENSPTRP00000092611annotation not available (106 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.