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CK820_G0012168 CK820_G0012168 ENSPTRP00000092364 ENSPTRP00000092364 FAM83B FAM83B ENSPTRP00000090382 ENSPTRP00000090382 PDPK1 PDPK1 BRAF-2 BRAF-2 PIK3CA PIK3CA PTK2 PTK2 AKT1 AKT1 KIF16B KIF16B BCAR1 BCAR1 BRAF BRAF TGFA TGFA ENSPTRP00000077211 ENSPTRP00000077211 SRC SRC ENSPTRP00000074763 ENSPTRP00000074763 ENSPTRP00000073371 ENSPTRP00000073371 PTPN11-2 PTPN11-2 ABL1 ABL1 REPS2 REPS2 GRB7 GRB7 ERBB2 ERBB2 EGFR EGFR EFEMP1 EFEMP1 ENSPTRP00000067174 ENSPTRP00000067174 GAREM1 GAREM1 SHC3 SHC3 ERBIN ERBIN ERBB4 ERBB4 AREG AREG SOCS5 SOCS5 PTPN11 PTPN11 PLCE1 PLCE1 ADAM17 ADAM17 GAREM2 GAREM2 SOS1 SOS1 SHC1 SHC1 PIGR PIGR FAM83A FAM83A PTK2B PTK2B HBEGF HBEGF CAMLG CAMLG GAB1 GAB1 EGF EGF BTC BTC EREG EREG EPGN EPGN PLCG1 PLCG1 RASSF2 RASSF2 DGKD DGKD VIL1 VIL1 NCK2 NCK2 TGFB1 TGFB1 GRB2 GRB2 SOX9 SOX9 IQGAP1 IQGAP1 CBL CBL PIK3C2A PIK3C2A SLC30A10 SLC30A10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CK820_G0012168ABL1 isoform 3. (1149 aa)
ENSPTRP00000092364annotation not available (574 aa)
FAM83BFamily with sequence similarity 83 member B. (1011 aa)
ENSPTRP00000090382annotation not available (493 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
BRAF-2BRAF isoform 2. (766 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
KIF16BKIF16B isoform 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1392 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
TGFATGFA isoform 6. (193 aa)
ENSPTRP00000077211annotation not available (269 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000074763annotation not available (520 aa)
ENSPTRP00000073371annotation not available (431 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
REPS2RALBP1 associated Eps domain containing 2. (659 aa)
GRB7Growth factor receptor bound protein 7. (555 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1. (493 aa)
ENSPTRP00000067174annotation not available (502 aa)
GAREM1Family with sequence similarity 59, member A. (875 aa)
SHC3SHC3 isoform 2. (598 aa)
ERBINErbb2 interacting protein. (1419 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
AREGAREG isoform 2. (274 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
PLCE1Phosphoinositide phospholipase C. (2301 aa)
ADAM17ADAM17 isoform 3. (999 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (874 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SHC1SHC (Src homology 2 domain containing) transforming protein 1. (584 aa)
PIGRPIGR isoform 1. (764 aa)
FAM83AFamily with sequence similarity 83 member A. (434 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
HBEGFHeparin-binding EGF-like growth factor. (208 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
GAB1GRB2-associated-binding protein 1. (724 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
BTCBTC isoform 1. (178 aa)
EREGEREG isoform 1. (169 aa)
EPGNEpithelial mitogen. (154 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
RASSF2Ras association (RalGDS/AF-6) domain family member 2. (326 aa)
DGKDDiacylglycerol kinase. (1254 aa)
VIL1VIL1 isoform 1. (827 aa)
NCK2Cytoplasmic protein. (380 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
CBLCas-Br-M (Murine) ecotropic retroviral transforming sequence. (906 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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